Critical Reviews in Biotechnology,
Год журнала:
2024,
Номер
unknown, С. 1 - 21
Опубликована: Ноя. 26, 2024
The
biomolecular
condensates
(BCs)
formed
by
proteins
through
phase
separation
provide
the
necessary
space
and
raw
materials
for
orderly
progression
of
cellular
activities,
on
this
basis,
various
membraneless
organelles
(MLOs)
are
formed.
occurrence
eukaryotic
is
driven
multivalent
interactions
from
intrinsically
disordered
regions
(IDRs)
and/or
specific
protein/nucleic
acid
binding
domains
regulated
environmental
factors.
In
plant
animal
cells,
MLOs
involved
in
gene
expression
regulation,
stress
response,
mitotic
control
display
similar
functions
mechanisms.
contrast,
related
to
reproductive
development
immune
regulation
differs
significantly
between
two
kingdoms
owing
their
distinct
cell
structures
nutritional
patterns.
addition,
animals
plants
each
exhibit
unique
protein
such
as
neural
light
signal
response.
By
comparing
similarities
differences
formation
mechanism
functional
known
separation,
we
elucidated
its
importance
evolution,
differentiation,
adaptation
both
plants.
significance
studying
enhancing
biological
quality
life
has
been
further
emphasized.
Advanced Biotechnology,
Год журнала:
2024,
Номер
2(1)
Опубликована: Фев. 8, 2024
Alternative
splicing
(AS)
significantly
enriches
the
diversity
of
transcriptomes
and
proteomes,
playing
a
pivotal
role
in
physiology
development
eukaryotic
organisms.
With
continuous
advancement
high-throughput
sequencing
technologies,
an
increasing
number
novel
transcript
isoforms,
along
with
factors
related
to
their
associated
functions,
are
being
unveiled.
In
this
review,
we
succinctly
summarize
compare
different
mechanisms
across
prokaryotes
eukaryotes.
Furthermore,
provide
extensive
overview
recent
progress
various
studies
on
AS
covering
developmental
stages
diverse
plant
species
response
abiotic
stresses.
Additionally,
discuss
modern
techniques
for
studying
functions
quantification
transcripts,
as
well
protein
products.
By
integrating
genetic
studies,
quantitative
methods,
omics
techniques,
can
discover
isoforms
functional
factors,
thereby
enhancing
our
understanding
roles
modes
species.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Июль 26, 2024
Alternative
splicing
is
a
crucial
process
in
multicellular
eukaryote,
facilitated
by
the
assembly
of
spliceosomal
complexes
comprising
numerous
small
ribonucleoproteins.
At
an
early
stage,
U1C
thought
to
be
required
for
5′
splice
site
recognition
and
base
pairing.
However,
systematic
analysis
gene
family
response
developmental
cues
stress
conditions
has
not
yet
been
conducted
plants.
This
study
identified
114
genes
72
plant
species
using
basic
bioinformatics
analyses.
Phylogenetic
was
used
compare
protein
structures,
promoter
motifs,
tissue-
stress-specific
expression
levels,
revealing
their
functional
commonalities
or
diversity
cues,
such
as
embryonic
expression,
treatments,
including
drought
heat.
Fluorescence
quantitative
showed
that
changed
under
salt,
low
temperature,
drought,
Cd
rice
seedlings.
shoots
roots
consistent
different
conditions,
suggesting
complex
regulatory
mechanism.
research
provides
foundational
insights
into
family's
role
development
responses,
highlighting
potential
targets
future
studies.
