Coatings,
Год журнала:
2024,
Номер
14(9), С. 1084 - 1084
Опубликована: Авг. 23, 2024
This
literature
review
deals
with
the
electrophoretic
deposition
of
bioactive
glass
coatings
on
metallic
substrates
to
produce
bone
implants.
Biocompatible
materials,
such
as
titanium
alloys
or
stainless
steels,
are
commonly
used
replace
hard
tissue
functions
because
their
mechanical
properties
appropriate
for
load-bearing
applications.
However,
materials
barely
react
in
body.
They
need
a
surface
coating
trigger
beneficial
biological
and
chemical
reactions
physiological
environment.
Bioactive
aim
improve
bonding,
shorten
healing
process
after
implantation,
extend
lifespan
implant.
glasses,
45S5,
58S,
S53P4,
13-93,
70S30C,
amorphous
made
mixture
oxides
that
accepted
by
human
reactivity
Their
high
bioactivity
environment
induces
formation
strong
bonding
at
interface
between
implant
surrounding
tissue.
Electrophoretic
is
one
most
effective
solutions
deposit
uniform
low
temperatures.
article
begins
different
compositions
glasses
described
scientific
ability
support
repair.
The
second
part
details
stages
occurring
immersed
Then,
mechanisms
involved
implants
described.
last
current
developments
improving
adding
biocompatible
elements
glassy
structure.
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(3), С. 1167 - 1315
Опубликована: Янв. 1, 2024
Silicon-based
biomaterials
have
been
extensively
developed
in
the
past
decades.
The
classification,
characteristics,
multi-dimensional
design,
and
biomedical
applications
of
silicon-containing
are
comprehensively
elaborated.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(1), С. 126 - 126
Опубликована: Янв. 18, 2024
Resveratrol
is
a
polyphenolic
compound
that
has
gained
considerable
attention
in
the
past
decade
due
to
its
multifaceted
therapeutic
potential,
including
anti-inflammatory
and
anticancer
properties.
However,
efficacy
impeded
by
low
water
solubility,
dose-limiting
toxicity,
bioavailability,
rapid
hepatic
metabolism.
To
overcome
these
hurdles,
various
nanoparticles
such
as
organic
inorganic
nanoparticles,
liposomes,
polymeric
dendrimers,
solid
lipid
gold
zinc
oxide
zeolitic
imidazolate
frameworks,
carbon
nanotubes,
bioactive
glass
mesoporous
were
employed
deliver
resveratrol,
enhancing
against
types
of
cancer.
Resveratrol-loaded
nanoparticle
or
resveratrol-conjugated
administration
exhibits
excellent
potency
compared
free
resveratrol.
This
review
highlights
latest
developments
nanoparticle-based
delivery
systems
for
focusing
on
potential
limitations
associated
with
compound’s
bioavailability
effectiveness.
Advanced Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 16, 2024
Bioactive
glass
(BG)
is
a
class
of
biocompatible,
biodegradable,
multifunctional
inorganic
materials,
which
successfully
used
for
orthopedic
and
dental
applications,
with
several
products
already
approved
clinical
use.
Apart
from
exhibiting
osteogenic
properties,
BG
also
known
to
be
angiogenic
antibacterial.
Recently,
BG's
role
in
immunomodulation
has
been
gradually
revealed.
While
the
therapeutic
effect
mostly
reported
context
bone
skin-related
regeneration,
its
application
regenerating
other
tissues/organs,
such
as
muscle,
cartilage,
gastrointestinal
tissue,
explored
recently.
The
strategies
applying
have
expanded
powder
or
cement
form
more
advanced
fabrication
composite
polymer-BG
scaffold,
3D
printing
BG-loaded
BG-induced
extracellular
vesicle
production.
This
review
presents
concise
overview
recent
applications
regenerative
medicine.
Various
will
first
introduced.
Next,
various
bone,
tendon,
skin,
discussed.
Finally,
summarizing
tissue
regeneration
conclude,
outline
future
challenges
directions
translation
BG.
Abstract
Bacterial
infections
are
a
significant
obstacle
to
the
healing
of
acute
and
chronic
wounds,
such
as
diabetic
ulcers
burn
injuries.
Traditional
antibiotics
primary
treatment
for
bacterial
infections,
but
they
present
issues
antibiotic
resistance,
limited
efficacy,
potential
side
effects.
This
challenge
leads
exploration
nanozymes
alternative
therapeutic
agents.
Nanozymes
nanomaterials
with
enzyme‐like
activities.
Owing
their
low
production
costs,
high
stability,
scalability,
multifunctionality,
have
emerged
prominent
focus
in
antimicrobial
research.
Among
various
types
nanozymes,
metal‐based
offer
several
benefits,
including
broad‐spectrum
activity
robust
catalytic
properties.
Specifically,
copper‐based
(CuNZs)
shown
considerable
promoting
wound
healing.
They
exhibit
strong
effects,
reduce
inflammation,
enhance
tissue
regeneration,
making
them
highly
advantageous
use
care.
review
describes
dual
functions
CuNZs
combating
infection
facilitating
repair.
Recent
advancements
design
synthesis
CuNZs,
evaluating
promotion,
biosafety
both
vitro
vivo
on
basis
core
components,
critically
important.
International Journal of Ceramic Engineering & Science,
Год журнала:
2024,
Номер
6(2)
Опубликована: Янв. 4, 2024
Abstract
This
article
reviews
promising
studies
on
the
design,
manufacturing,
microstructure,
properties,
and
applications
of
glass‐ceramics
containing
ZrO
2
relevant
glass‐ceramic
matrix
composites.
After
addition
to
a
composition,
it
can
persist
in
residual
glassy
phase,
facilitate
nucleation,
and/or
precipitate
as
or
another
zirconate
crystalline
phase.
Also,
‐reinforced
‐toughened
be
designed
In
this
article,
term
“ZrO
‐containing
glass‐ceramics”
encompasses
all
these
scenarios
which
is
present.
Such
offer
wide
range
modern
industries,
including
but
not
limited
architecture,
optics,
dentistry,
medicine,
energy.
Since
S.
Donald
Stookey's
discovery
early
1950s,
most
important
scientific
efforts
reported
literature
are
reviewed.
commonly
added
promote
nucleation.
As
result,
role
structural
modification
glass
stimulating
nucleation
first
discussed.
also
into
main
phase
glass‐ceramics,
contributing
achieving
super
high
fracture
toughness
above
4
MPa·m
0.5
.
Experimental
computational
reviewed
detail
elucidate
how
transformation
toughening
other
mechanisms
help
achieve
such
values
toughness.
Sintered
composites
show
promise,
where
contributes
improved
stability
mechanical
properties.
Finally,
we
hope
will
provoke
interest
materials
both
industrial
communities
so
that
their
tremendous
technological
potential
developing,
for
example,
tough,
thermally
stable,
transparent,
biologically
compatible
realized
more
widely.
Biomaterials Science,
Год журнала:
2024,
Номер
12(10), С. 2521 - 2560
Опубликована: Янв. 1, 2024
Alkali
and
alkaline
earth
elements
play
a
crucial
role
in
the
structure,
processing,
properties
of
bioactive
glasses,
widely
used
medical
applications
since
their
inception
1969.
Advanced Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 27, 2025
Tissue
engineering
aims
to
repair
damaged
tissues
with
physiological
functions
recovery.
Although
several
therapeutic
strategies
are
there
for
tissue
regeneration,
the
functional
recovery
of
regenerated
still
poses
significant
challenges
due
lack
concerns
innervation.
Design
rationale
multifunctional
biomaterials
both
tissue-induction
and
neural
induction
activities
shows
great
potential
regeneration.
Recently,
research
application
inorganic
attracts
increasing
attention
in
innervated
multi-tissue
such
as
central
nerves,
bone,
skin,
because
its
superior
tunable
chemical
composition,
topographical
structures,
physiochemical
properties.
More
importantly,
easily
combined
other
organic
materials,
biological
factors,
external
stimuli
enhance
their
effects.
This
review
presents
a
comprehensive
overview
recent
advancements
It
begins
introducing
classification
properties
typical
design
inorganic-based
material
composites.
Then,
progresses
regenerating
various
nerves
nerve-innervated
systematically
reviewed.
Finally,
existing
future
perspectives
proposed.
may
pave
way
direction
offers
new
strategy
regeneration
combination
Journal of Clinical Medicine,
Год журнала:
2025,
Номер
14(6), С. 1838 - 1838
Опубликована: Март 8, 2025
Bone
regeneration
has
emerged
as
a
critical
research
and
clinical
advancement
field,
fueled
by
the
growing
demand
for
effective
treatments
in
orthopedics
oncology.
Over
past
two
decades,
significant
progress
biomaterials
surgical
techniques
led
to
development
of
novel
solutions
treating
bone
defects,
surpassing
use
traditional
autologous
grafts.
This
review
aims
assess
latest
approaches
regeneration,
including
autologous,
allogenic,
xenogenic
grafts,
naturally
derived
biomaterials,
innovative
synthetic
substitutes
such
bioceramics,
bioactive
glasses,
metals,
polymers,
composite
materials,
other
specialized
applications.
A
comprehensive
literature
search
was
conducted
on
PubMed,
focusing
studies
published
between
2019
2024,
meta-analyses,
reviews,
systematic
reviews.
The
evaluated
range
strategies,
examining
outcomes,
materials
used,
techniques,
effectiveness
various
defects.
identified
numerous
studies,
with
inclusion
criteria
focused
those
exploring
strategies.
These
provided
valuable
insights
into
biological
outcomes
different
graft
types.
Results
indicated
that
while
advancements
show
promising
potential,
challenges
remain
optimizing
therapeutic
strategies
across
diverse
patient
populations
settings.
findings
emphasize
need
an
integrated
approach
combines
scientific
research,
practice,
technological
innovation
improve
therapies.
Further
is
required
establish
standardized
protocols
determine
optimal
application
enhance
quality
care.
