Glucose-triggered NIR-responsive photothermal antibacterial gelatin/dextran hydrogel simultaneously targeting the high glucose and infection microenvironment in diabetic wound

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140325 - 140325

Опубликована: Янв. 1, 2025

Язык: Английский

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Facile preparation of carboxymethyl chitosan/dextran/poly(ionic liquid)-based hydrogel with intrinsic antibacterial and antioxidant properties for accelerating skin wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 304, С. 140851 - 140851

Опубликована: Фев. 9, 2025

Язык: Английский

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Injectable Antibacterial Drug-Free Hydrogel Dressing Enabled by a Bioactive Peptide-Mimicking Synthetic Peptidyl Polymer

Acta Biomaterialia, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Salvia Miltiorrhiza Protocatechualdehyde: Killing Efficacy and Metabolic Regulation Mechanism in Ampicillin-Resistant Escherichia Coli

Опубликована: Янв. 1, 2025

Язык: Английский

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Porous Sodium Carboxymethyl Starch Microspheres for Hemostasis and Skin Wound Healing

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 3, 2025

An effective and rapid hemostatic material with flexible properties for clinical wound dressings is still an unmet need. Herein, a porous sodium carboxymethyl starch (CMS-Na-P) microsphere was successfully fabricated through polysaccharide fluffy aggregate (PSFA) technology facile low-cost process. CMS-Na-P exhibited water absorption capabilities alongside favorable cytocompatibility hemocompatibility. Additionally, could absorb red blood cells (RBCs), adhere to activate platelets, shorten clotting time in vitro. More importantly, its good vivo ability further demonstrated against hemorrhage rat liver tail, pig superficial skin, body vein, abdominal femoral artery. Meanwhile, full-thickness skin defect model, enhance healing accelerated epidermal regeneration collagen deposition. These make promising candidate treating bleeding wounds.

Язык: Английский

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An Antifreezing Scaffold‐Based Cryopreservation Platform of Stem Cells for Convenient Application in Wound Repair

Advanced Healthcare Materials, Год журнала: 2024, Номер 14(4)

Опубликована: Дек. 26, 2024

Efficient cryopreservation of stem cells is crucial to fabricating off-the-shelf cell products for tissue engineering and regeneration medicine. However, it remains challenging due utilization toxic cryoprotectants reducing ice-related cryodamages during freeze-thaw cycle, stringent post-thaw washing process, further integration with scaffolds form constructs downstream applications. Herein, a novel platform based on an antifreezing polyvinylpyrrolidone/gellan gum/gelatin (PGG) scaffold together reported L-proline assisted pre-dehydration strategy. Results show that this capable inhibiting extra-/intracellular ice, thus can achieve high cryoprotection efficacy (≈95%) without using any eliminate traditional process. Meanwhile, the post-thawed maintain their proliferation, differentiation, paracrine functionalities. More importantly, biocompatibility three dimensional structure PGG scaffold, cell-laden be directly used as wound repair by mitigating inflammation promoting collagen deposition at regenerating sites. This present work demonstrates feasibility scaffold-based cells, which may advance clinical translation.

Язык: Английский

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Enhancing wound treatment with superoxide dismutase-loaded solid lipid nanoparticles

Burns, Год журнала: 2024, Номер unknown, С. 107195 - 107195

Опубликована: Июль 1, 2024

Язык: Английский

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