Advances in Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 103529 - 103529
Опубликована: Апрель 1, 2025
Язык: Английский
Advances in Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 103529 - 103529
Опубликована: Апрель 1, 2025
Язык: Английский
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160379 - 160379
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160509 - 160509
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1Advanced Materials, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
Diabetic wounds are refractory and recurrent diseases that necessitate the development of multifunctional dressings. Inspired by structure function skin, we herein delicately design a novel swollen hydrophobic hydrogel (QL@MAB) composed methyl acrylate (MA) (3-acrylamidophenyl)boronic acid (AAPBA) network co-loaded with antioxidant quercetin (Q) antibiotic levofloxacin (L) for efficient diabetic wound therapy. The MA segments undergo phase separation to form dense "epidermis", ensuring prolonged drug diffusion, long-term water retention, high content. Meanwhile, AAPBA generate glucose-labile "sweat pores" via borate ester bonds polyphenol Q. Upon encountering hyperglycemic microenvironment, dilated due cleavage exposure diffusion channel, facilitating release accelerated healing. In infected rats, QL@MAB achieves rapid debridement re-epithelization while promoting angiogenesis, hair follicle regeneration, extracellular matrix remodeling. Taken together, this study not only represents multipronged dressing effective interventions but also contributes rational smart hydrogels tailored biomedical applications.
Язык: Английский
Процитировано
1Chinese Herbal Medicines, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0Journal of Materials Chemistry B, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
A new class of ultrasound-induced piezoionic hydrogels with antibacterial and antioxidant properties are developed to accelerate infected diabetic wound healing.
Язык: Английский
Процитировано
0Acta Biomaterialia, Год журнала: 2025, Номер unknown
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Gels, Год журнала: 2025, Номер 11(4), С. 293 - 293
Опубликована: Апрель 15, 2025
As an intelligent polymer material, pH-sensitive hydrogels exhibit the capability to dynamically sense alterations in ambient pH levels and subsequently initiate corresponding physical or chemical responses, including swelling, contraction, degradation, ion exchange. Given significant variations inherent human pathophysiological microenvironments, particularly tumor tissues, inflammatory lesions, gastrointestinal system, these smart materials demonstrate remarkable application potential across diverse domains such as targeted drug delivery systems, regenerative medicine engineering, biosensing, disease diagnostics. Recent breakthroughs nanotechnology precision have substantially propelled advancements design of pH-responsive hydrogels. This review systematically elaborates on current research progress future challenges regarding biomedical applications, with particular emphasis their stimulus–response mechanisms, fabrication methodologies, multifunctional integration strategies, scenarios.
Язык: Английский
Процитировано
0Materials Today Chemistry, Год журнала: 2025, Номер 46, С. 102720 - 102720
Опубликована: Апрель 23, 2025
Язык: Английский
Процитировано
0Journal of Colloid and Interface Science, Год журнала: 2025, Номер 694, С. 137669 - 137669
Опубликована: Апрель 24, 2025
Язык: Английский
Процитировано
0Advances in Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 103529 - 103529
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
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