Abstract
Transdermal
drug
delivery
systems
based
on
physical
principles
have
provided
a
stable,
efficient,
and
safe
strategy
for
disease
therapy.
However,
the
intelligent
device
with
real‐time
control
precise
release
is
required
to
enhance
treatment
efficacy
improve
patient
compliance.
This
review
summarizes
recent
developments,
application
scenarios,
characteristics
of
smart
transdermal
fabricated
principle.
Special
attention
paid
progress
design
concepts
in
physical‐based
technologies
monitoring
release.
In
addition,
facing
needs
clinical
personalized
medicine,
trend
enhancement
are
further
highlighted
combination
pharmaceutical
dosage
forms
achieve
better
effects
facilitate
development
medical
devices.
Finally,
next
generation
future
scenarios
discussed,
particular
focus
vaccine
tumor
treatment.
Abstract
Global
increasing
demand
for
high
life
quality
and
length
facilitates
the
development
of
tissue
engineering
regenerative
medicine,
which
apply
multidisciplinary
theories
techniques
to
achieve
structural
reconstruction
functional
recovery
disordered
or
damaged
tissues
organs.
However,
clinical
performances
adopted
drugs,
materials,
powerful
cells
in
laboratory
are
inescapably
limited
by
currently
available
technologies.
To
tackle
problems,
versatile
microneedles
developed
as
new
platform
local
delivery
diverse
cargos
with
minimal
invasion.
The
efficient
delivery,
well
painless
convenient
procedure
endow
good
patient
compliance
clinic.
In
this
review,
we
first
categorize
different
microneedle
systems
models,
then
summarize
their
applications
medicine
mainly
involving
maintenance
rehabilitation
end,
discuss
advantages,
challenges,
prospects
depth
future
translations.
Advanced Materials,
Год журнала:
2022,
Номер
34(27)
Опубликована: Янв. 10, 2022
Abstract
The
primary
roles
of
precision
medicine
are
to
perform
real‐time
examination,
administer
on‐demand
medication,
and
apply
instruments
continuously.
However,
most
current
therapeutic
systems
implement
these
processes
separately,
leading
treatment
interruption
limited
recovery
in
patients.
Personalized
healthcare
smart
medical
have
greatly
promoted
research
on
development
biosensing
drug‐delivery
integrated
systems,
with
intelligent
wearable
devices
(IWMDs)
as
typical
which
received
increasing
attention
because
their
non‐invasive
customizable
nature.
Here,
the
latest
progress
IWMDs
is
reviewed,
including
mechanisms
integrating
drug
delivery.
challenges
future
directions
also
discussed.
Advances in healthcare information systems and administration book series,
Год журнала:
2024,
Номер
unknown, С. 308 - 326
Опубликована: Фев. 9, 2024
This
chapter
explores
the
ever-changing
environment
of
wearable
health
technology
and
its
critical
role
in
transforming
modern
healthcare.
It
goes
into
historical
history
these
devices,
tracking
their
path
from
basic
fitness
trackers
to
sophisticated
health-monitoring
systems,
focusing
on
proactive
preventative
management.
The
present
scene
emphasizes
range
breadth
accessible
discusses
sensor
improvements,
biometric
monitoring,
wireless
communications.
These
advancements
have
significantly
improved
precision
effectiveness
monitoring
numerous
markers.
also
thoroughly
reviews
use
devices
remote
patient
emphasizing
revolutionary
influence
chronic
illness
management
senior
care
through
real-world
case
studies.
Furthermore,
investigates
integration
device
data
healthcare
systems
for
real-time
covering
technological
infrastructure
issues.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 3, 2025
Abstract
This
review
underscores
the
transformative
potential
of
photonic
nanomaterials
in
wearable
health
technologies,
driven
by
increasing
demands
for
personalized
monitoring.
Their
unique
optical
and
physical
properties
enable
rapid,
precise,
sensitive
real‐time
monitoring,
outperforming
conventional
electrical‐based
sensors.
Integrated
into
ultra‐thin,
flexible,
stretchable
formats,
these
materials
enhance
compatibility
with
human
body,
enabling
prolonged
wear,
improved
efficiency,
reduced
power
consumption.
A
comprehensive
exploration
is
provided
integration
devices,
addressing
material
selection,
light‐matter
interaction
principles,
device
assembly
strategies.
The
highlights
critical
elements
such
as
form
factors,
sensing
modalities,
data
communication,
representative
examples
skin
patches
contact
lenses.
These
devices
precise
monitoring
management
biomarkers
diseases
or
biological
responses.
Furthermore,
advancements
approaches
have
paved
way
continuum
care
systems
combining
multifunctional
sensors
therapeutic
drug
delivery
mechanisms.
To
overcome
existing
barriers,
this
outlines
strategies
design,
engineering,
system
integration,
machine
learning
to
inspire
innovation
accelerate
adoption
next‐generation
health,
showcasing
their
versatility
digital
applications.
Wearables
and
bioelectronics
rely
on
breathable
interface
devices
with
bioaffinity,
biocompatibility,
smart
functionality
for
interactions
between
beings
things
the
surrounding
environment.
Elastic
fibers/fabrics
mechanical
adaptivity
to
various
deformations
complex
substrates,
are
promising
act
as
fillers,
carriers,
dressings,
scaffolds
in
construction
of
biointerfaces
human
body,
skins,
organs,
plants,
realizing
functions
such
energy
exchange,
sensing,
perception,
augmented
virtuality,
health
monitoring,
disease
diagnosis,
intervention
therapy.
This
review
summarizes
highlights
latest
breakthroughs
elastic
wearables
bioelectronics,
aiming
offer
insights
into
elasticity
mechanisms,
production
methods,
electrical
components
integration
strategies
fibers/fabrics,
presenting
a
profile
management,
sensors,
e-skins,
thermal
personal
protection,
wound
healing,
biosensing,
drug
delivery.
The
trans-disciplinary
application
from
biomedicine
provides
important
inspiration
technology
transplantation
function
adapt
different
systems.
As
discussion
platform,
here
main
challenges
possible
solutions
field
proposed,
hopefully
can
provide
guidance
promoting
development
e-textiles
consideration
trade-off
mechanical/electrical
performance,
industrial-scale
production,
diverse
environmental
adaptivity,
multiscenario
on-spot
applications.
