Nano Today, Год журнала: 2023, Номер 48, С. 101750 - 101750
Опубликована: Янв. 5, 2023
Язык: Английский
Chemical Engineering Journal, Год журнала: 2022, Номер 454, С. 140277 - 140277
Опубликована: Ноя. 11, 2022
Язык: Английский
Процитировано
92
Chemosphere, Год журнала: 2022, Номер 311, С. 137056 - 137056
Опубликована: Ноя. 1, 2022
Язык: Английский
Процитировано
91
Coordination Chemistry Reviews, Год журнала: 2023, Номер 479, С. 215002 - 215002
Опубликована: Янв. 10, 2023
Язык: Английский
Процитировано
81
Nano-Micro Letters, Год журнала: 2022, Номер 14(1)
Опубликована: Июнь 14, 2022
MXenes, transition metal carbides and nitrides with graphene-like structures, have received considerable attention since their first discovery. On the other hand, Graphene has been extensively used in biomedical medicinal applications. MXene graphene, both as promising candidates of two-dimensional materials, shown to possess high potential future applications due unique physicochemical properties such superior electrical conductivity, biocompatibility, large surface area, optical magnetic features, extraordinary thermal mechanical properties. These special structural, functional, biological characteristics suggest that hybrid/composite structure graphene would be able meet many unmet needs different fields; particularly medicine engineering, where high-performance mechanical, electrical, thermal, magnetic, requirements are necessary. However, hybridization functionalization should further explored obtain biocompatible composites/platforms properties, stability, multifunctionality. In addition, toxicological long-term biosafety assessments clinical translation evaluations given priority research. Although very limited studies revealed excellent potentials MXene/graphene biomedicine, next steps toward extensive research detailed analysis optimizing improving functionality a industrial outlook. Herein, synthesis/fabrication methods performances composites discussed for The effects these on human cells tissues also covered, perspectives more successful translational presented. current state-of-the-art biotechnological advances use MXene-Graphene composites, well developmental challenges prospects deliberated. Due multifunctionality MXene-graphene hybrid structures can open up new horizons healthcare medicine.
Язык: Английский
Процитировано
79
Ceramics International, Год журнала: 2022, Номер 48(17), С. 24144 - 24156
Опубликована: Май 14, 2022
Язык: Английский
Процитировано
74
ACS Nano, Год журнала: 2023, Номер 17(8), С. 7229 - 7240
Опубликована: Апрель 5, 2023
The bone defects caused by trauma are inevitably accompanied soft tissue damage. development of multifunctional bioactive biomaterials with integrated and regeneration is necessary needed urgently in orthopedics. In this work, we found that the photoactivated MXene (Ti3C2Tx) nanosheet showed positive effects on promoting both regeneration. We further investigated detailed effect potential mechanism Photoactivated shows a good thermal robust antibacterial activity to inhibit expression inflammation factors methicillin-resistant Staphylococcus aureus (MRSA) infection induces pro-angiogenic wound repair. can also regulate osteogenic differentiation adipose-derived stem cells (ADSCs) through ERK signaling pathway activating heat shock protein 70 (HSP70) enhancing repair tissue. This work sheds light photothermal activation as an efficient strategy for simultaneously.
Язык: Английский
Процитировано
53
Nanoscale, Год журнала: 2023, Номер 15(9), С. 4170 - 4194
Опубликована: Янв. 1, 2023
Transition metal carbides/nitrides (MXenes) are emerging two-dimensional (2D) materials that have been widely investigated in recent years.
Язык: Английский
Процитировано
49
Chemical Reviews, Год журнала: 2024, Номер 124(13), С. 8307 - 8472
Опубликована: Июнь 26, 2024
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been extensively developed physical tool for versatile biomedical applications. Especially, prosperity of nanotechnology nanomedicine invigorates landscape ultrasound-based medicine. The unprecedented surge in research enthusiasm dedicated efforts have led mass multifunctional micro-/nanosystems being applied biomedicine, facilitating precise diagnosis, effective treatment, personalized theranostics. deployment applications is rooted profound understanding relationship among composition, structure, property, bioactivity, application, performance. In this comprehensive review, we elaborate on general principles regarding design, synthesis, functionalization, optimization abundant particular, recent advancements imaging are meticulously summarized. Furthermore, systematically elucidate state-of-the-art studies concerning progress therapeutic targeting various pathological abnormalities including cancer, bacterial infection, brain diseases, cardiovascular metabolic diseases. Finally, conclude provide an outlook field with in-depth discussion challenges faced future developments further extensive clinical translation application.
Язык: Английский
Процитировано
32
Nature Communications, Год журнала: 2024, Номер 15(1)
Опубликована: Янв. 26, 2024
Abstract A wearable biological patch capable of producing multiple responses to light and electricity without interfering with daily activities is highly desired for skin cancer treatment, but remains a key challenge. Herein, the skin-mountable electrostimulation-augmented photothermal (eT-patch) comprising transparent ionic gel MXene (Ti 3 C 2 T x) doping developed applied treatment melanoma under photostimulation at 0.5 W/cm . The eT-patch designed has superior electrical characteristics owing gels doped which provides high conversion efficiency conductivity as medium. Simultaneously, gel-based having excellent optical transparency actualizes real-time observation response process stimulation (PES) co-therapy. Systematical cellular study on anti-tumor mechanism PES revealed that can synergically trigger cell apoptosis pyroptosis, together lead death cells. Due obvious advantages relatively safe less side effects in healthy organs, promising cost-effective therapeutic strategy tumors will open new avenue biomedical applications gels.
Язык: Английский
Процитировано
27
ACS Sensors, Год журнала: 2024, Номер 9(4), С. 1706 - 1734
Опубликована: Апрель 2, 2024
The development of advanced technologies for the fabrication functional nanomaterials, nanostructures, and devices has facilitated biosensors analyses. Two-dimensional (2D) with unique hierarchical structures, a high surface area, ability to be functionalized target detection at surface, exhibit potential biosensing applications. electronic properties, mechanical flexibility, optical, electrochemical, physical properties 2D nanomaterials can easily modulated, enabling construction platforms various analytes targeted recognition, sensitivity, selectivity. This review provides an overview recent advances in nanostructures used biosensor wearable-sensor healthcare health-monitoring Finally, advantages 2D-nanomaterial-based several challenges their optimal operation have been discussed facilitate smart high-performance future.
Язык: Английский
Процитировано
16