Introduction to Nanofabrication for Theranostics Application

Опубликована: Янв. 1, 2024

Язык: Английский

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Establishment of a stem cell administration imaging method in bleomycin-induced pulmonary fibrosis mouse models

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Авг. 14, 2024

Pulmonary fibrosis is a progressive disease caused by interstitial inflammation. Treatments are extremely scarce; therapeutic drugs and transplantation therapies not widely available due to cost lack of donors, respectively. Recently, there has been high interest in regenerative medicine exponential advancements stem cell-based have occurred. However, sensitive imaging technique for investigating the vivo dynamics transplanted cells yet established mechanisms therapy remain largely unexplored. In this study, we administered mouse adipose tissue-derived mesenchymal (mASCs) labeled with quantum dots (QDs; 8.0 nM) model bleomycin-induced pulmonary an effort clarify relationship between efficacy. These QD-labeled mASCs were injected into trachea C57BL/6 mice seven days after bleomycin administration induce lungs. The effects efficacy evaluated via vivo/ex imaging, CT H&E staining lung sections. remained lungs longer suppressed fibrosis. 3D results showed that accumulated peripheral fibrotic regions indicate may prevent Thus, QD labeling could be suitable evaluating kinetics correlation cell therapy.

Язык: Английский

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Advanced Uses of Quantum Dots in Medical Imaging

Опубликована: Янв. 1, 2024

Язык: Английский

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Current Context of Designing Phototheranostic Cyclometalated Iridium (III) Complexes to Open a New Avenue in Cancer Therapy

ChemMedChem, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 4, 2024

Abstract Photo‐induced chemotherapy offers the best option for selective treatment of cancer among all prevailing modalities. Iridium (III) complexes, flourished with excellent photophysical and photochemical properties, have been considered to be superior undergoing photo‐responsive therapy. Large Stokes shift, long‐lived triplet excited state, photostability, tuneable emission rendered its excellence as a phototheranostic agent. In particular, cyclometalated Ir complexes their respective nanoparticles made strong niche in arena recent years, based shown promising utilities both imaging therapeutic agents well. Therefore, this review summarises advances strategic designing Ir(III) augment applications precision medicine.

Язык: Английский

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Preface in special theme: Functional inorganic nanomaterials for cutting-edge theranostic applications

Advanced Drug Delivery Reviews, Год журнала: 2023, Номер 199, С. 114991 - 114991

Опубликована: Июль 4, 2023

Язык: Английский

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