Advanced Drug Delivery Reviews, Journal Year: 2023, Volume and Issue: 199, P. 114991 - 114991
Published: July 4, 2023
Language: Английский
Advanced Drug Delivery Reviews, Journal Year: 2023, Volume and Issue: 199, P. 114991 - 114991
Published: July 4, 2023
Language: Английский
Published: Jan. 1, 2024
Language: Английский
Citations
0Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Aug. 14, 2024
Pulmonary fibrosis is a progressive disease caused by interstitial inflammation. Treatments are extremely scarce; therapeutic drugs and transplantation therapies not widely available due to cost lack of donors, respectively. Recently, there has been high interest in regenerative medicine exponential advancements stem cell-based have occurred. However, sensitive imaging technique for investigating the vivo dynamics transplanted cells yet established mechanisms therapy remain largely unexplored. In this study, we administered mouse adipose tissue-derived mesenchymal (mASCs) labeled with quantum dots (QDs; 8.0 nM) model bleomycin-induced pulmonary an effort clarify relationship between efficacy. These QD-labeled mASCs were injected into trachea C57BL/6 mice seven days after bleomycin administration induce lungs. The effects efficacy evaluated via vivo/ex imaging, CT H&E staining lung sections. remained lungs longer suppressed fibrosis. 3D results showed that accumulated peripheral fibrotic regions indicate may prevent Thus, QD labeling could be suitable evaluating kinetics correlation cell therapy.
Language: Английский
Citations
0Published: Jan. 1, 2024
Language: Английский
Citations
0ChemMedChem, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 4, 2024
Abstract Photo‐induced chemotherapy offers the best option for selective treatment of cancer among all prevailing modalities. Iridium (III) complexes, flourished with excellent photophysical and photochemical properties, have been considered to be superior undergoing photo‐responsive therapy. Large Stokes shift, long‐lived triplet excited state, photostability, tuneable emission rendered its excellence as a phototheranostic agent. In particular, cyclometalated Ir complexes their respective nanoparticles made strong niche in arena recent years, based shown promising utilities both imaging therapeutic agents well. Therefore, this review summarises advances strategic designing Ir(III) augment applications precision medicine.
Language: Английский
Citations
0Advanced Drug Delivery Reviews, Journal Year: 2023, Volume and Issue: 199, P. 114991 - 114991
Published: July 4, 2023
Language: Английский
Citations
0