Lessons learnt from broad-spectrum coronavirus antiviral drug discovery

Expert Opinion on Drug Discovery, Год журнала: 2024, Номер 19(9), С. 1023 - 1041

Опубликована: Июль 30, 2024

Introduction Highly pathogenic coronaviruses (CoVs), such as severe acute respiratory syndrome CoV (SARS-CoV), Middle East (MERS-CoV), and the most recent SARS-CoV-2 responsible for COVID-19 pandemic, pose significant threats to human populations over past two decades. These CoVs have caused a broad spectrum of clinical manifestations ranging from asymptomatic distress syndromes (ARDS), resulting in high morbidity mortality.

Язык: Английский

Association of IFNAR2 and TYK2 with COVID-19 pathology: current and future

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Сен. 16, 2024

Язык: Английский