Complex Issues of Cardiovascular Diseases, Год журнала: 2024, Номер 13(1), С. 98 - 108
Опубликована: Март 29, 2024
Highlights The article presents a modern understanding of the main links functional circulatory regulation system and its response to exogenous hypoxia, as well describes data available on molecular mechanisms vasoprotection cardioprotection involved in hypoxytherapy patients with arterial hypertension coronary artery disease. Abstract Hypoxic conditioning has taken an important place range non-drug methods for stimulating adaptive potential healthy person cardiovascular diseases. There are many approaches use various however, there is no consensus essence sanogenetic that provide multi-level maintaining oxygen supply blood circulation. Adaptive reactions afferent, central efferent hypoxia described. results studies physiological systemic realized by respiratory vegetative plasticity using interval (intermittent) presented. In disease, facts chemoreflective stimulation modulation lung ventilation, autonomic nervous status, especially sympathetic activity peripheral vessels vagal activation cardiac have been established. vaso- cardioprotective properties based leveling oxidative stress, inflammation, angiogenesis, shift secretory endothelium towards vasodilating, antiproliferative, antithrombotic mediators. We present evidence role shear stress state glycocalyx, angiopoietin adrenomedulline vascular tone, cytoprotective cytoplasmic mitochondrial metabolic factors formation ischemic tolerance cardiomyocytes. issues relationship between (neuronal humoral) structural responses target cells providing adaptive/compensatory regulating circulation under influence require further research evaluation.
Язык: Английский
Процитировано
0Radiology Case Reports, Год журнала: 2024, Номер 19(9), С. 3740 - 3747
Опубликована: Июнь 17, 2024
Язык: Английский
Процитировано
0Springer eBooks, Год журнала: 2024, Номер unknown, С. 663 - 677
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0Cureus, Год журнала: 2024, Номер unknown
Опубликована: Авг. 10, 2024
Background Cardiovascular diseases (CVDs), including coronary artery disease, heart attacks, strokes, and hypertension, are the leading cause of global morbidity mortality. Despite advancements in diagnostic techniques, treatment protocols, public health initiatives, prevalence CVD continues to rise. Hence, understanding trends predisposing factors for current modalities such as medication use frequency hospitalization is essential developing effective interventions improving strategies. This study leverages Behavioral Risk Factor Surveillance System (BRFSS) data analyze these among adults older than 18 years. Methods Data were sourced from BRFSS database, analyzing patterns 2019 2021. The included with high cholesterol or blood pressure, stroke, failure. analysis utilized age-adjusted prevalence, mortality, rates. Results revealed several key There was a statistically significant increase (p<0.05) taking cholesterol, rising 28.9% 31%, controlling increasing 57.7% 60.4%. From 2021, disease mortality increased 360,900 382,820, while stroke deaths rose 150,005 162,890. Trends show both conditions despite missing some Mortality rates also (p<0.05), 88 92.8 cases per 100,000, 37 41.1 100,000. Hospitalization failure Medicare beneficiaries aged 65 initially decreased 2020, likely due COVID-19 pandemic impacting hospital admissions, but again 2021 healthcare-seeking behaviors normalized. Significant gender racial disparities observed, higher males (127.4 100,000) Black, non-Hispanic individuals (110.5 100,000). Conclusions highlights pressure years, yet persist. observed. These findings underscore need targeted intervention towards adherence addressing social determinants health, reduce burden enhance equity across diverse populations.
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0