Pharmaceutical intervention for hypertension in a rural district of the Republic of Zambia: a model-based economic evaluation DOI Creative Commons
Yuta Yokobori, Manuela Deidda, Francesco Manca

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(9), P. e084575 - e084575

Published: Sept. 1, 2024

Objectives In Zambia, 19.1% of the adult population had elevated blood pressure. Hence, Ministry Health in Zambia designated improvement hypertension (HTN) care services as a priority policy. However, there are limited data on cost-effective interventions to address HTN and their budget impact sub-Saharan Africa. The objective this paper is investigate cost-effectiveness primary-level for (pharmaceutical treatments) compared with no treatment, impact, Chongwe District, rural Zambia. Methods A cost–utility analysis was undertaken from perspective healthcare provider, employing cohort Markov model lifetime horizon. developed populated evidence literature, including novel locally collected cost data. run overall aged 40 years above subpopulations stratified by three levels risk gender District using directly collected. probabilistic performed assess probability cost-effectiveness. Results dominant treatment general combination therapy diuretics calcium blockers. incremental ratio US$1114 treatment. This most first-line medication all subgroup populations, except subgroups classified low-risk defined WHO. estimated annual US$1 015 605 total if patients received Considering only material costs, US$29 435. Conclusion blockers population. From local government could need secure approximately US$30 000 facilitate delivery medications entire over need.

Language: Английский

Breast calcifications on mammography from systemic amyloidosis: A case report DOI Creative Commons
Joanna Rossi,

Rebecca Wingfield,

Ashley Cimino‐Mathews

et al.

Radiology Case Reports, Journal Year: 2024, Volume and Issue: 19(9), P. 3740 - 3747

Published: June 17, 2024

Language: Английский

Citations

0

Evolution of Nursing Practice Roles DOI

Raechel Ferry-Rooney,

Jennifer S. White,

Kristen Coleman

et al.

Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 663 - 677

Published: Jan. 1, 2024

Language: Английский

Citations

0

Association of Cardiologist Clinic Visits with Cardiovascular Primary Prevention Outcomes Among People with HIV from Underrepresented Racial and Ethnic Groups in the Southern United States DOI Creative Commons
Matthew S. Durstenfeld, C. Larry Hill,

Robert M. Clare

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 9, 2024

Abstract Background People with HIV (PWH) are at elevated risk for atherosclerotic cardiovascular disease (ASCVD). Underrepresented racial and ethnic groups (UREGs) in the southern U.S. disproportionately affected, yet whether cardiology specialist care this at-risk group improves blood pressure lipid control or prevents events is unknown. Methods We evaluated a cohort of PWH from UREGs ASCVD without known who received HIV-related 2015–2018 four academic medical centers Southern United States follow up through 2020. Primary outcomes were (<140/90 mmHg) (LDL-C ≤ 100 mg/dl) over 2 years time to first major adverse (MACE) event. Statistical analyses adjusted cohort/site patient factors including measures comorbidities. Results Among 3972 included (median age 47 old, 32.6% female) diagnosed disease, 276 (6.9%) had clinic visit. Cardiology visits not significantly associated subsequent (adjusted OR 0.78, 95% CI 0.49-1.24, p=0.29) 2.25, 0.72-7.01, p=0.16). Over median 5 years, patients visit higher MACE, overall mortality, falsification endpoints (hospitalization death accident/trauma pneumonia/sepsis) indicating overall, even after adjusting measured factors. Conclusions UREG risk, was improved reduced events. Our study suggests that seeing cardiologist alone sufficient promote health prevent among PWH, but low confidence given those What known? increased burden both high people underrepresented live States. Treating statins reduces adds? States, better control, prevention attended mortality.

Language: Английский

Citations

0

Cardiovascular Disease Patterns, Mortality, and Hospitalization Trends in Adults Over 18: Insights From the Behavioral Risk Factor Surveillance System Database DOI Open Access
Okelue E Okobi,

Enyioma Nwogwugwu,

Cosmas O Ihezie

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 10, 2024

Background Cardiovascular diseases (CVDs), including coronary artery disease, heart attacks, strokes, and hypertension, are the leading cause of global morbidity mortality. Despite advancements in diagnostic techniques, treatment protocols, public health initiatives, prevalence CVD continues to rise. Hence, understanding trends predisposing factors for current modalities such as medication use frequency hospitalization is essential developing effective interventions improving strategies. This study leverages Behavioral Risk Factor Surveillance System (BRFSS) data analyze these among adults older than 18 years. Methods Data were sourced from BRFSS database, analyzing patterns 2019 2021. The included with high cholesterol or blood pressure, stroke, failure. analysis utilized age-adjusted prevalence, mortality, rates. Results revealed several key There was a statistically significant increase (p<0.05) taking cholesterol, rising 28.9% 31%, controlling increasing 57.7% 60.4%. From 2021, disease mortality increased 360,900 382,820, while stroke deaths rose 150,005 162,890. Trends show both conditions despite missing some Mortality rates also (p<0.05), 88 92.8 cases per 100,000, 37 41.1 100,000. Hospitalization failure Medicare beneficiaries aged 65 initially decreased 2020, likely due COVID-19 pandemic impacting hospital admissions, but again 2021 healthcare-seeking behaviors normalized. Significant gender racial disparities observed, higher males (127.4 100,000) Black, non-Hispanic individuals (110.5 100,000). Conclusions highlights pressure years, yet persist. observed. These findings underscore need targeted intervention towards adherence addressing social determinants health, reduce burden enhance equity across diverse populations.

Language: Английский

Citations

0

Pharmaceutical intervention for hypertension in a rural district of the Republic of Zambia: a model-based economic evaluation DOI Creative Commons
Yuta Yokobori, Manuela Deidda, Francesco Manca

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(9), P. e084575 - e084575

Published: Sept. 1, 2024

Objectives In Zambia, 19.1% of the adult population had elevated blood pressure. Hence, Ministry Health in Zambia designated improvement hypertension (HTN) care services as a priority policy. However, there are limited data on cost-effective interventions to address HTN and their budget impact sub-Saharan Africa. The objective this paper is investigate cost-effectiveness primary-level for (pharmaceutical treatments) compared with no treatment, impact, Chongwe District, rural Zambia. Methods A cost–utility analysis was undertaken from perspective healthcare provider, employing cohort Markov model lifetime horizon. developed populated evidence literature, including novel locally collected cost data. run overall aged 40 years above subpopulations stratified by three levels risk gender District using directly collected. probabilistic performed assess probability cost-effectiveness. Results dominant treatment general combination therapy diuretics calcium blockers. incremental ratio US$1114 treatment. This most first-line medication all subgroup populations, except subgroups classified low-risk defined WHO. estimated annual US$1 015 605 total if patients received Considering only material costs, US$29 435. Conclusion blockers population. From local government could need secure approximately US$30 000 facilitate delivery medications entire over need.

Language: Английский

Citations

0