BMJ Open,
Journal Year:
2024,
Volume and Issue:
14(9), P. e084575 - e084575
Published: Sept. 1, 2024
Objectives
In
Zambia,
19.1%
of
the
adult
population
had
elevated
blood
pressure.
Hence,
Ministry
Health
in
Zambia
designated
improvement
hypertension
(HTN)
care
services
as
a
priority
policy.
However,
there
are
limited
data
on
cost-effective
interventions
to
address
HTN
and
their
budget
impact
sub-Saharan
Africa.
The
objective
this
paper
is
investigate
cost-effectiveness
primary-level
for
(pharmaceutical
treatments)
compared
with
no
treatment,
impact,
Chongwe
District,
rural
Zambia.
Methods
A
cost–utility
analysis
was
undertaken
from
perspective
healthcare
provider,
employing
cohort
Markov
model
lifetime
horizon.
developed
populated
evidence
literature,
including
novel
locally
collected
cost
data.
run
overall
aged
40
years
above
subpopulations
stratified
by
three
levels
risk
gender
District
using
directly
collected.
probabilistic
performed
assess
probability
cost-effectiveness.
Results
dominant
treatment
general
combination
therapy
diuretics
calcium
blockers.
incremental
ratio
US$1114
treatment.
This
most
first-line
medication
all
subgroup
populations,
except
subgroups
classified
low-risk
defined
WHO.
estimated
annual
US$1
015
605
total
if
patients
received
Considering
only
material
costs,
US$29
435.
Conclusion
blockers
population.
From
local
government
could
need
secure
approximately
US$30
000
facilitate
delivery
medications
entire
over
need.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 9, 2024
Abstract
Background
People
with
HIV
(PWH)
are
at
elevated
risk
for
atherosclerotic
cardiovascular
disease
(ASCVD).
Underrepresented
racial
and
ethnic
groups
(UREGs)
in
the
southern
U.S.
disproportionately
affected,
yet
whether
cardiology
specialist
care
this
at-risk
group
improves
blood
pressure
lipid
control
or
prevents
events
is
unknown.
Methods
We
evaluated
a
cohort
of
PWH
from
UREGs
ASCVD
without
known
who
received
HIV-related
2015–2018
four
academic
medical
centers
Southern
United
States
follow
up
through
2020.
Primary
outcomes
were
(<140/90
mmHg)
(LDL-C
≤
100
mg/dl)
over
2
years
time
to
first
major
adverse
(MACE)
event.
Statistical
analyses
adjusted
cohort/site
patient
factors
including
measures
comorbidities.
Results
Among
3972
included
(median
age
47
old,
32.6%
female)
diagnosed
disease,
276
(6.9%)
had
clinic
visit.
Cardiology
visits
not
significantly
associated
subsequent
(adjusted
OR
0.78,
95%
CI
0.49-1.24,
p=0.29)
2.25,
0.72-7.01,
p=0.16).
Over
median
5
years,
patients
visit
higher
MACE,
overall
mortality,
falsification
endpoints
(hospitalization
death
accident/trauma
pneumonia/sepsis)
indicating
overall,
even
after
adjusting
measured
factors.
Conclusions
UREG
risk,
was
improved
reduced
events.
Our
study
suggests
that
seeing
cardiologist
alone
sufficient
promote
health
prevent
among
PWH,
but
low
confidence
given
those
What
known?
increased
burden
both
high
people
underrepresented
live
States.
Treating
statins
reduces
adds?
States,
better
control,
prevention
attended
mortality.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 10, 2024
Background
Cardiovascular
diseases
(CVDs),
including
coronary
artery
disease,
heart
attacks,
strokes,
and
hypertension,
are
the
leading
cause
of
global
morbidity
mortality.
Despite
advancements
in
diagnostic
techniques,
treatment
protocols,
public
health
initiatives,
prevalence
CVD
continues
to
rise.
Hence,
understanding
trends
predisposing
factors
for
current
modalities
such
as
medication
use
frequency
hospitalization
is
essential
developing
effective
interventions
improving
strategies.
This
study
leverages
Behavioral
Risk
Factor
Surveillance
System
(BRFSS)
data
analyze
these
among
adults
older
than
18
years.
Methods
Data
were
sourced
from
BRFSS
database,
analyzing
patterns
2019
2021.
The
included
with
high
cholesterol
or
blood
pressure,
stroke,
failure.
analysis
utilized
age-adjusted
prevalence,
mortality,
rates.
Results
revealed
several
key
There
was
a
statistically
significant
increase
(p<0.05)
taking
cholesterol,
rising
28.9%
31%,
controlling
increasing
57.7%
60.4%.
From
2021,
disease
mortality
increased
360,900
382,820,
while
stroke
deaths
rose
150,005
162,890.
Trends
show
both
conditions
despite
missing
some
Mortality
rates
also
(p<0.05),
88
92.8
cases
per
100,000,
37
41.1
100,000.
Hospitalization
failure
Medicare
beneficiaries
aged
65
initially
decreased
2020,
likely
due
COVID-19
pandemic
impacting
hospital
admissions,
but
again
2021
healthcare-seeking
behaviors
normalized.
Significant
gender
racial
disparities
observed,
higher
males
(127.4
100,000)
Black,
non-Hispanic
individuals
(110.5
100,000).
Conclusions
highlights
pressure
years,
yet
persist.
observed.
These
findings
underscore
need
targeted
intervention
towards
adherence
addressing
social
determinants
health,
reduce
burden
enhance
equity
across
diverse
populations.
BMJ Open,
Journal Year:
2024,
Volume and Issue:
14(9), P. e084575 - e084575
Published: Sept. 1, 2024
Objectives
In
Zambia,
19.1%
of
the
adult
population
had
elevated
blood
pressure.
Hence,
Ministry
Health
in
Zambia
designated
improvement
hypertension
(HTN)
care
services
as
a
priority
policy.
However,
there
are
limited
data
on
cost-effective
interventions
to
address
HTN
and
their
budget
impact
sub-Saharan
Africa.
The
objective
this
paper
is
investigate
cost-effectiveness
primary-level
for
(pharmaceutical
treatments)
compared
with
no
treatment,
impact,
Chongwe
District,
rural
Zambia.
Methods
A
cost–utility
analysis
was
undertaken
from
perspective
healthcare
provider,
employing
cohort
Markov
model
lifetime
horizon.
developed
populated
evidence
literature,
including
novel
locally
collected
cost
data.
run
overall
aged
40
years
above
subpopulations
stratified
by
three
levels
risk
gender
District
using
directly
collected.
probabilistic
performed
assess
probability
cost-effectiveness.
Results
dominant
treatment
general
combination
therapy
diuretics
calcium
blockers.
incremental
ratio
US$1114
treatment.
This
most
first-line
medication
all
subgroup
populations,
except
subgroups
classified
low-risk
defined
WHO.
estimated
annual
US$1
015
605
total
if
patients
received
Considering
only
material
costs,
US$29
435.
Conclusion
blockers
population.
From
local
government
could
need
secure
approximately
US$30
000
facilitate
delivery
medications
entire
over
need.