Biogenic synthesis and characterization of antimicrobial, antioxidant, and antihemolytic zinc oxide nanoparticles from Desertifilum sp. TN-15 cell extract DOI Creative Commons

Taswar Nadeem,

Muhammad Kaleem, Lubna Anjum Minhas

и другие.

Discover Nano, Год журнала: 2024, Номер 19(1)

Опубликована: Окт. 2, 2024

Abstract Cyanobacteria, being a prominent category of phototrophic organism, exhibit substantial potential as valuable source bioactive compounds and phytonutrients, including liposomes, amino derivatives, proteins, carotenoids. In this investigation, polyphasic approach was employed to isolate characterize newly discovered cyanobacterial strain from rice field in the Garh Moor district Jhang. Desertifilum sp. TN-15, unique less explored strain, holds significant promise novel candidate for synthesis nanoparticles. This noticeable research gap underscores novelty untapped TN-15 nanomedicine. The characterization biogenically synthesized ZnO–NPs involved application diverse analytical techniques. Ultraviolet–visible spectroscopy revealed surface plasmon resonance peak at 298 nm. Fourier transform infrared spectral analysis utilized confirm involvement biomolecules biogenic stability. Scanning electron microscopy probe morphology unveiling their size 94.80 nm star-shaped. Furthermore, X-ray diffraction substantiated crystalline nature ZnO–NPs, with measuring 46 To assess physical stability zeta dynamic light scattering measurements were conducted, yielding values + 31.6 mV, nm, respectively, indicative favorable antibacterial capabilities are attributed its abundance components, Through zinc oxide nanoparticles (ZnO–NPs) we have effectively used these chemicals generate that noteworthy activity against Staphylococcus aureus (MIC: 30.05 ± 0.003 µg/ml). Additionally, displayed potent antifungal antioxidant properties, well antihemolytic effects on red blood cells (IC 50 : 4.8 Cytotoxicity assessment using brine shrimps an IC value 3.1 µg/ml. multifaceted actions underscore applications pharmacological therapeutic fields. study proposes method production utilizing recently identified highlighting growing significance biological systems environmentally friendly fabrication metallic nanomaterials.

Язык: Английский

Targeting Metabolic Diseases: The Role of Nutraceuticals in Modulating Oxidative Stress and Inflammation DOI Open Access

Aida Dama,

Kleva Shpati, Patricia Daliu

и другие.

Nutrients, Год журнала: 2024, Номер 16(4), С. 507 - 507

Опубликована: Фев. 10, 2024

The escalating prevalence of metabolic and cardiometabolic disorders, often characterized by oxidative stress chronic inflammation, poses significant health challenges globally. As the traditional therapeutic approaches may sometimes fall short in managing these conditions, attention is growing toward nutraceuticals worldwide; with compounds being obtained from natural sources potential beneficial effects shown to potentially support and, some cases, replace pharmacological treatments, especially for individuals who do not qualify conventional treatments. This review delves into burgeoning field nutraceutical-based modulation as a promising strategy attenuating inflammation disorders. Drawing an extensive body research, showcases various nutraceutical agents, such polyphenols, omega-3 fatty acids, antioxidants, which exhibit antioxidative anti-inflammatory properties. All can be classified novel drugs that are capable regulating pathways mitigate oxidative-stress- inflammation-associated diseases. By exploring mechanisms through interact immune responses, this highlights their restore redox balance temper inflammation. Additionally, prospects interventions discussed, encompassing bioavailability enhancement, personalized treatment approaches, clinical translation. Through comprehensive analysis latest scientific reports, article underscores avenue fight complex landscape particularly accentuating impact on cardiovascular health.

Язык: Английский

Процитировано

36

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview DOI Creative Commons
Tabussam Tufail,

Huma Bader Ul Ain,

Sana Noreen

и другие.

Food Science & Nutrition, Год журнала: 2024, Номер 12(11), С. 8715 - 8741

Опубликована: Окт. 16, 2024

Certain carotene components, such as lycopene and beta-carotene, are found in tomatoes, carrots, sweet potatoes, etc. good for human health. It gives plants their distinctive red color. A class of lipid-soluble natural pigments known carotenoids is the precursor vitamin vital antioxidant defense against peroxides cells tissues. This review provides an overview current state knowledge research on sources, structures, physiochemical properties, absorption metabolism, functional advantages, prevention many diseases associated with beta-carotene. These antioxidants have been linked to a lower risk cardiovascular disease cancer, they also help draw pollinators flowers. Carrots potatoes rich sources which strengthens immune system improves eye The vivid color reproductive organs, including flowers fruits, caused by carotenoid, secondary metabolite that produced plastids. other health advantages attributed lycopene. When ingested through food or supplements, beta-carotene manage prevent number diseases, metabolic, inflammatory, cardiovascular, hepatic, ophthalmic, skeletal, infertility disorders. main point toxicity uncommon, these generally accepted be safe at different doses. Including nutrients your diet can improve general provide illness prevention.

Язык: Английский

Процитировано

12

Anti-Inflammatory Effects of Algae-Derived Biomolecules in Gut Health: A Review DOI Open Access
Antonella Brizzi,

Rosaria Margherita Rispoli,

Giuseppina Autore

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(3), С. 885 - 885

Опубликована: Янв. 21, 2025

Under physiological conditions, the inflammatory response acts as a biological defense against tissue damage or infection, and is rapidly resolved once infection cleared. However, chronic diseases, including bowel disease (IBD), have become increasingly widespread in last decades, placing burden on quality of life affected people healthcare systems worldwide. Available drug therapies are often ineffective due to nature these prolonged administration drugs can result severe side effects for patient lack efficacy. In addition, there growing problem bacterial resistance synthetic antibiotics. Together, factors led strong research focus discovery natural products capable treating IBD. Recently, has been interest compounds derived from marine sources, mainly algae, their bioactive secondary metabolites with anti-inflammatory properties well known literature. Based this evidence, review aimed evaluate potential algae-derived biomolecules particular, interesting species green algae (e.g., Chlorella vulgaris Ulva pertusa), brown Macrocystis pyrifera Ecklonia cava) red Porphyra tenera Grateloupia turuturu) included proven properties. For purpose, an extensive literature search was conducted using several databases. The results suggest that both macroalgae microalgae remarkable IBD therapy antioxidant activities compounds. while preclinical evidence encouraging, further long-term clinical studies needed better understand mechanisms action order determine true efficacy treatment

Язык: Английский

Процитировано

1

Sustainable Synthesis of Cobalt Oxide Nanoparticles (Co3O4-NPs) Using Extract of Nodosilinea nodulosa: Characterization and Potential Biological Applications DOI

Faiqa Aslam,

Lubna Anjum Minhas, Muhammad Kaleem

и другие.

BioNanoScience, Год журнала: 2024, Номер 14(5), С. 4764 - 4778

Опубликована: Июль 30, 2024

Язык: Английский

Процитировано

6

The molecular complexity of terpene biosynthesis in red algae: current state and future perspectives DOI Creative Commons
Wanessa Francesconi Stida, Renato Crespo Pereira,

Esthfanny dos Santos Souza Azevedo

и другие.

Natural Product Reports, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

In this article, we review the key processes contributing to chemical diversity of terpenes in red algae. We present knowledge gaps and perspectives for heterologous biosynthesis.

Язык: Английский

Процитировано

0

Gracilaria edulis-mediated silver nanoparticles as a targeted strategy for cervical cancer with integrated toxicity evaluation in zebrafish DOI

Nandita Ravichandran,

Deenathayalan Uvarajan,

Manish Ravikumar

и другие.

Bioorganic Chemistry, Год журнала: 2025, Номер 159, С. 108361 - 108361

Опубликована: Март 11, 2025

Язык: Английский

Процитировано

0

Current and Prospective Pharmaceutical Use of Algal Bioproducts DOI Creative Commons

Edwin H. W. Leung

IntechOpen eBooks, Год журнала: 2025, Номер unknown

Опубликована: Март 13, 2025

This chapter explores the diverse applications of algal biocompounds in human health, focusing on dietary, cosmetic, and pharmaceutical uses. Algae, ranging from macroscopic kelp to microscopic single-celled organisms (including cyanobacteria), are a rich source bioactive compounds with potential benefits for health well-being. begins by classifying algae highlighting their historical use as food. It then delves into current prospective biocompounds, dividing discussion three main sections. The first section examines dietary uses food supplements additives, role sources macro- micronutrients, natural colourings, thickeners prebiotics. second external extracts cosmetics, discussing anti-aging, whitening, moisturizing, thickening, photoprotection, antioxidant activity hair care. Finally, third investigates examining antimicrobial, anti-inflammatory activities, hypertension management, direct cancer treatment indirect aids, diagnostic use. aims provide comprehensive overview state research commercial contribute sustainable solutions, enhance cosmetic products, develop novel pharmaceuticals.

Язык: Английский

Процитировано

0

Influence of Algal Biomass Chemical Composition on Hydrothermal Liquefaction Efficiency and Its Implications for A549 Cell Line Cytotoxicity DOI

T. L. Ajith,

Mythili Ravichandran,

Salim Manoharadas

и другие.

Waste and Biomass Valorization, Год журнала: 2025, Номер unknown

Опубликована: Апрель 28, 2025

Язык: Английский

Процитировано

0

Anabaena sp. A‐1 mediated molybdenum oxide nanoparticles: A novel frontier in green synthesis, characterization and pharmaceutical properties DOI

Hafiza Aliya Malik,

Lubna Anjum Minhas, Muhammad Waqar Hassan

и другие.

Microscopy Research and Technique, Год журнала: 2024, Номер 87(9), С. 1999 - 2012

Опубликована: Апрель 16, 2024

Green-synthesized metal oxide nanoparticles have garnered considerable attention due to their simple, sustainable, and eco-friendly attributes, coupled with diverse applications in biomedicine environmental context. The current study shows a sustainable approach for synthesizing molybdenum (MoONPs) utilizing an extract from Anabaena sp. A-1. This novel marks significant milestone as various spectral approaches were employed characterization of the green-synthesized MoONPs. Ultraviolet-visible (UV-Vis) spectroscopic analysis revealed surface plasmon resonance (SPR) peak MoONPs at 538 nm. Fourier transform infrared (FTIR) facilitated identification functional groups responsible both stability production Scanning electron microscopy (SEM) was utilized revealing rod shape morphology X-ray diffraction (XRD) yielded calculated crystal size 31 nm, indicating crystalline nature Subsequently, biological assays ascertain potential bioengineered 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay used quantify free radical scavenging activity, antioxidant capacity 68.1% 200 μg/mL. To evaluate antibacterial antifungal efficacy, disc diffusion method across varying concentrations (6.25, 12.5, 25, 50, 100, 150, μg/mL). Quantification cytotoxicity performed via brine shrimp assay, yielding IC50 value 552.3 μg/mL, metric moderate cytotoxicity. assess biocompatibility MoONPs, antihemolytic conducted, confirming safety profile. Additionally, exhibited non-toxic attributes insecticidal assay. Notably, anti-inflammatory showed inactive towards reactive oxygen species. In conclusion, these findings highlight versatility applications, extending beyond recognized properties. RESEARCH HIGHLIGHTS: advancement nanotechnology, exploring ways fabrication, representing unique unexplored research domain. using A-1 offers approach. Characterized by UV-Vis, FTIR, SEM, XRD, demonstrate rod-shaped nature. Bioengineered exhibit demonstrating notable antioxidant, cytotoxicity, biocompatibility, properties, emphasizing multifaceted utility. utilization spectrum thereby suggesting promising role realm

Язык: Английский

Процитировано

3

Advancements and environmental impact of hydrothermal processing of algal biomass DOI

R. Sivaranjanee,

P. Senthil Kumar,

Gayathri Rangasamy

и другие.

Biomass Conversion and Biorefinery, Год журнала: 2024, Номер unknown

Опубликована: Сен. 5, 2024

Язык: Английский

Процитировано

0