What doesn’t kill us makes us stronger: insights from neuroscience studies and molecular genetics

Current Opinion in Behavioral Sciences, Год журнала: 2024, Номер 59, С. 101431 - 101431

Опубликована: Июль 22, 2024

Язык: Английский

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Effects of Health-Promoting Lifestyle on Late-Onset Depression in Older Adults: Mediating Effect of Meaning in Life and Interleukin-6 (IL-6)

Psychology Research and Behavior Management, Год журнала: 2023, Номер Volume 16, С. 5159 - 5168

Опубликована: Дек. 1, 2023

Purpose: Late-onset depression (LOD) with poor treatment response has high incidence and mortality in the China's aged people, this study aims to explore correlation between health-promoting lifestyle, meaning life, interleukin-6 (IL-6) LOD for providing scientific basis of prevention rehabilitation. Patients Methods: A total 496 patients (study group) healthy older adults (control were enrolled investigated by using Health-promoting lifestyle Profile-II, revised (HPLP-IIR), Meaning Life Questionnaire-Chinese Version (MLQ-C), Hamilton Depression Scale (HAMD). The circulating blood was detected utilizing ELISA kit. Results: results showed that scores all factors HPLP-IIR MLQ significantly lower IL-6 level higher group than control group. Scores most negatively positively correlated subscales HAMD score. life partially mediated relationship lifestyles severity group, mediating effect explains 15.76% 22.64% effect, respectively. Conclusion: lifestyles, are predictors LOD, an unhealthy could induce through adults. Keywords: late-onset depression, adult

Язык: Английский

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Identification of Relationships Among Resilience Factors Using Network Analysis: A Pilot Study

Journal of the American Psychiatric Nurses Association, Год журнала: 2023, Номер unknown

Опубликована: Ноя. 23, 2023

BACKGROUND: Although college life can be fulfilling, it stressful, particularly for health professional students. In addition, they may have had Adverse Childhood Experience (ACE) that increases their sensitivity to academic stress. Yet, students need overcome challenges become successful professionals. The literature suggests the following factors associated with resilience: ACE and stress as antecedents; ego-resilience, emotion regulation, resources, social support, inflammatory markers, genes defining attributes; mental sense of coherence (SOC) consequences. AIMS: purpose is identify relationships among resilience using network analysis. METHODS: A total 70 participated in this cross-sectional pilot study. They completed measures psychosocial variables provided saliva samples, which were analyzed Serotonin Transporter-Linked Promoter Region (5-HTTLPR)/rs25531 markers. Mixed graphical models including all estimated R-package mgm. RESULTS: Network analysis revealed positive associations between (1) SOC; (2) resources; (3) support; (4) SOC reappraisal regulation; (5) resources (6) support. negatively associated. Furthermore, short variant 5-HTTLPR/rs25531 was stronger suppression regulation fewer compared long variant. CONCLUSION: Resilience influenced by biopsychosocial factors, notably 5-HTTLPR/rs25531. However, longitudinal research needed a larger sample size better understand how these other affect resilience.

Язык: Английский

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Analyzing the relationships among psychosocial variables associated with resilience

Archives of Psychiatric Nursing, Год журнала: 2024, Номер 53, С. 33 - 41

Опубликована: Окт. 3, 2024

Язык: Английский

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