Macrophage-Hitchhiked, Effervescence-Induced Nanoemulsions for Enhanced Oral Chemotherapy and Immunotherapy: Impact on Absorption Route

Biomaterials, Год журнала: 2024, Номер 316, С. 123019 - 123019

Опубликована: Дек. 15, 2024

Язык: Английский

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Formation mechanism of herpetrione self-assembled nanoparticles based on pH-driven method

Chinese Chemical Letters, Год журнала: 2024, Номер 36(1), С. 109733 - 109733

Опубликована: Март 7, 2024

Язык: Английский

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Reactive Oxygen Species Responsive Paclitaxel-PEG Nano-Prodrug for Treatment of Metastatic Breast Cancer

ACS Applied Nano Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 17, 2024

Язык: Английский

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Engineering Docetaxel Micelles for Enhanced Cancer Therapy Through Intermolecular Forces

Bioengineering, Год журнала: 2024, Номер 11(11), С. 1078 - 1078

Опубликована: Окт. 28, 2024

Docetaxel has exhibited excellent therapeutic effects in cancer treatment; however, its hydrophobicity, short blood circulation time, and high toxicity restrict clinical application. The use of mPEG-PLA micelles to deliver docetaxel into the body been verified as an effective approach enhance efficacy. However, are easily disassembled bloodstream, which can lead premature drug release. To broaden application scenarios mPEG PLA micelles, we utilized π–π stacking effect intermolecular force design a novel mPEG-PLA-Lys(Fmoc) micelle stability permeability drug-loaded micelles. result showed that for injection did not alter tissue selectivity docetaxel. Intravenous nude mice better antitumor efficacy than tumor recurrence rate is 0%, significantly lower (100%). designed by this research institute anticipated improve

Язык: Английский

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A Novel Self-Assembled Paclitaxel Nanodispersion Facilitates Rapid In-Vitro/In-Vivo Dissociation and Protein Binding

AAPS PharmSciTech, Год журнала: 2024, Номер 26(1)

Опубликована: Дек. 5, 2024

Язык: Английский

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