Intrinsic and extrinsic pathways of apoptosis induced by multiple antibiotics residues and ocean acidification in hemocytes of scallop Argopecten irradians irradians: An interactionist perspective DOI Creative Commons
Tianyu Zhang, Xin Wang, Qianqian Zhang

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2023, Номер 269, С. 115806 - 115806

Опубликована: Дек. 12, 2023

The increasing prevalence of antibiotics in seawater across global coastal areas, coupled with the ocean acidification induced by climate change, present a multifaceted challenge to marine ecosystems, particularly impacting key physiological processes organisms. Apoptosis is critical adaptive response essential for maintaining cellular homeostasis and defending against environmental threats. In this study, bay scallops Argopecten irradians were exposed multiple (sulfamethoxazole, tetracycline, oxytetracycline, norfloxacin, erythromycin, each at concentration 1 μg/L) combined with/without acidic (pH 7.6) 35 days. single interactive effects two stressors on apoptosis underlying mechanisms hemocytes A. determined through flow cytometry analysis, comet assay, oxidative stress biomarkers transcriptome analysis. Results showed that could be triggered either AM exposure or OA exposure, but different pathways. Exposure leads mitochondrial dysfunction damage, which turn triggers via series events both intrinsic extrinsic Conversely, while similarly apoptosis, its are comparatively subdued predominantly mediated pathway. Additionally, synergistic pronounced damages irradians. Despite evident distress potential initiation apoptotic pathways, actual execution appears restrained, might attributed an energy deficit within hemocytes. Our findings underscore constrained tolerance capacity when faced stressors, shed light ecotoxicity antibiotic pollution under prospective change scenarios.

Язык: Английский

Responses of the intestinal microbiota to exposure of okadaic acid in marine medaka Oryzias melastigma DOI
Yongmeng Yang, Aifeng Li, Jiangbing Qiu

и другие.

Journal of Hazardous Materials, Год журнала: 2023, Номер 465, С. 133087 - 133087

Опубликована: Ноя. 24, 2023

Язык: Английский

Процитировано

9

Effects of microorganisms, temperature and irradiation on the stability of dissolved okadaic acid and dinophysistoxin-1 in seawater DOI
Jiangbing Qiu, Chao Yin, Aifeng Li

и другие.

Marine Environmental Research, Год журнала: 2025, Номер unknown, С. 106969 - 106969

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Effects of Dinoflagellate Toxins Okadaic Acid and Dinophysistoxin-1 and -2 on the Microcrustacean Artemia franciscana DOI Creative Commons
Federica Cavion, Silvio Sosa, Jane Kilcoyne

и другие.

Toxins, Год журнала: 2025, Номер 17(2), С. 80 - 80

Опубликована: Фев. 10, 2025

Harmful algal blooms are an expanding phenomenon negatively impacting human health, socio-economic welfare, and ecosystems. Such events increase the risk of marine organisms' exposure to toxins with consequent ecological effects. In this frame, objective study was investigate ecotoxicological potential three globally distributed dinoflagellate (okadaic acid, OA; dinophysistoxin-1, DTX-1; dinophysistoxin-2, DTX-2) using Artemia franciscana as a model organism zooplankton. Each toxin (0.1-100 nM) evaluated for its toxic effects in terms cyst hatching, mortality nauplii Instar I adults, biochemical responses related oxidative stress. At highest concentration (100 nM), these significantly increased adults' starting from 24 h (DTX-1), 48 (OA), or 72 (DTX-2) exposures, DTX-1 being most potent one, followed by OA DTX-2. The quantitation stress biomarkers i.e., reactive oxygen species (ROS) production activity endogenous antioxidant defense enzymes (glutathione S-transferase, superoxide dismutase, catalase) showed that only DTX-2 ROS production, whereas each affected different profile. general, results indicate negative impact towards A. consequences on ecosystem.

Язык: Английский

Процитировано

0

Effects of okadaic acid on Pyropia yezoensis: Evidence from growth, photosynthesis, oxidative stress and transcriptome analysis DOI
Ruolin Wu, Jiangbing Qiu,

Xianghai Tang

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 491, С. 137902 - 137902

Опубликована: Март 11, 2025

Язык: Английский

Процитировано

0

Differential developmental effects and its potential mechanism of long-term exposure to TBBPA in two generations of marine medaka (Oryzias melastigma) during early life stages DOI
Teng Wang, Shuai Liu, Zhengyan Li

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 137961 - 137961

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Spatial distribution of lipophilic shellfish toxins in seawater and sediment in the Bohai Sea and the Yellow Sea, China DOI

Dongyue Li,

Jiangbing Qiu, Xiaoyun Wang

и другие.

Chemosphere, Год журнала: 2024, Номер 362, С. 142780 - 142780

Опубликована: Июль 5, 2024

Язык: Английский

Процитировано

2

Effects of the harmful algal bloom toxin, okadaic acid, on the mechanoreceptors of larval anchoveta (Engraulis ringens) under varying environmental conditions DOI Creative Commons

Piera Pepe-Vargas,

Leonardo R. Castro, Catharina Alves‐de‐Souza

и другие.

Frontiers in Marine Science, Год журнала: 2024, Номер 11

Опубликована: Окт. 7, 2024

The effect of the combination marine toxins produced by algal blooms, in conjunction with varying environmental characteristics on organisms water column, is a poorly explored research field. Pelagic fish species commercial importance, such as anchoveta ( Engraulis ringens ) central Chile, may be exposed to these combined factors climate change scenario. This observed from documented changes length upwelling season, frequency events, and increased atmospheric rivers affecting southern spawning zone this species. study evaluated integrity hair cells neuromasts, mechanosensory organs present larvae, under exposure different combinations bloom-produced okadaic acid OA (1 ng mL −1 ), two temperature (12 14°C), salinity treatments (historically more frequent: 34 PSU- 12°C; expected: 32 PSU - 14°C). Viable were counted newly hatched larvae Biobío region, Chile. Results showed significant decrease average number viable per neuromast (from 6.1 ± 1.6 4.0 1.2) lower (32 PSU) compared normal conditions. Additionally, seasonal trend was fewer 7.4 1.2 4.4 1.1) species’ reproductive period progressed. modifications also resulted up 70% high temperatures, indicating damage influenced toxin along synergistic and/or additive role temperature. These findings reveal how lipophilic acid, harmful interacts abiotic coastal ecologically socio-economically important organisms. emphasizes need consider multiple when studying effects toxins.

Язык: Английский

Процитировано

2

Intrinsic and extrinsic pathways of apoptosis induced by multiple antibiotics residues and ocean acidification in hemocytes of scallop Argopecten irradians irradians: An interactionist perspective DOI Creative Commons
Tianyu Zhang, Xin Wang, Qianqian Zhang

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2023, Номер 269, С. 115806 - 115806

Опубликована: Дек. 12, 2023

The increasing prevalence of antibiotics in seawater across global coastal areas, coupled with the ocean acidification induced by climate change, present a multifaceted challenge to marine ecosystems, particularly impacting key physiological processes organisms. Apoptosis is critical adaptive response essential for maintaining cellular homeostasis and defending against environmental threats. In this study, bay scallops Argopecten irradians were exposed multiple (sulfamethoxazole, tetracycline, oxytetracycline, norfloxacin, erythromycin, each at concentration 1 μg/L) combined with/without acidic (pH 7.6) 35 days. single interactive effects two stressors on apoptosis underlying mechanisms hemocytes A. determined through flow cytometry analysis, comet assay, oxidative stress biomarkers transcriptome analysis. Results showed that could be triggered either AM exposure or OA exposure, but different pathways. Exposure leads mitochondrial dysfunction damage, which turn triggers via series events both intrinsic extrinsic Conversely, while similarly apoptosis, its are comparatively subdued predominantly mediated pathway. Additionally, synergistic pronounced damages irradians. Despite evident distress potential initiation apoptotic pathways, actual execution appears restrained, might attributed an energy deficit within hemocytes. Our findings underscore constrained tolerance capacity when faced stressors, shed light ecotoxicity antibiotic pollution under prospective change scenarios.

Язык: Английский

Процитировано

3