Royal Society of Chemistry eBooks,
Год журнала:
2024,
Номер
unknown, С. 251 - 285
Опубликована: Ноя. 15, 2024
The
encapsulation
of
active
pharmaceutical
ingredients
(APIs)
in
microbeads
is
an
essential
step
drug
delivery;
however,
it
also
inherently
associated
with
the
need
to
control
particle
size
and
release
profiles.
Nevertheless,
most
conventional
methods
microencapsulation
fail
provide
consistent
results.
A
new
method
called
vibration-assisted
microbead
coating
a
novel
unified
technique
utilizing
mechanical
vibrations
enable
controlled,
uniform
on
APIs.
This
chapter
discusses
technology
performed
by
authors
through
formation
physical
activity
focuses
achieving
final
coated
surface
API,
shape,
size,
loading
vibration
parameters.
Additionally,
this
biocompatibility
stability
surface.
means
has
high
potential
for
delivery.
reduces
traditional
challenges
encapsulation,
if
not
eliminates
them,
more
reliable.
Based
abovementioned
findings,
propose
following
main
areas
their
further
work:
optimisation
parameters
various
APIs,
research
into
long-term
loading–release
profile,
possible
use
targeted
Applied Biological Chemistry,
Год журнала:
2024,
Номер
67(1)
Опубликована: Дек. 21, 2024
Abstract
Plastic
pollution
is
of
critical
environmental
concern,
thus
biodegradable
plastics
(BPs)
have
emerged
as
a
potential
solution
to
limit
plastic
waste
accumulation.
However,
the
fate
BPs
in
environment,
particularly
their
degradation
and
subsequent
generation
microplastic
(BMP)
particles,
remains
poorly
understood.
This
review
aims
provide
comprehensive
insights
into
biodegradation
process
impacts
on
soil
freshwater
environments.
Microorganisms
play
pivotal
role
this
by
dismantling
polymer
chains
smaller
particles.
Factors
influencing
rates
include
composition,
conditions
(e.g.,
temperature,
ultraviolet
radiation
(UV),
pH),
presence
chemical
additives.
incomplete
can
result
BMPs,
potentially
perpetuating
environment
posing
risks
ecosystems
organisms.
consolidates
understanding
mechanisms
governing
BMP
formation,
which
imperative
for
evaluating
consequences
devising
effective
strategies
managing
waste.
