Biological and Behavioural Effects of Bisphenol A (BPA) Exposure: An In Vivo Study in Drosophila melanogaster DOI Creative Commons
Isabel Gaivão, Rita António Santos, Тетяна Морозова

и другие.

Applied Sciences, Год журнала: 2025, Номер 15(10), С. 5588 - 5588

Опубликована: Май 16, 2025

Bisphenol A (BPA) is one of the most produced compounds worldwide. It acts as an endocrine disruptor and can cause adverse effects in body, even at low-dose exposures. By interacting with estrogen receptors, it play important role pathogenesis several diseases, such infertility, hormone-dependent tumours various metabolic disorders. Exposure humans, especially early life, particular concern, since have a big impact on individual’s development growth. The objective this study was to evaluate, vivo, genotoxicity BPA its longevity, prolificacy behaviour Drosophila melanogaster. To evaluate biological behavioural effects, flies were crossed subjected different concentrations (0.5 mM, 1 2 5 mM 10 mM) instant “Carolina” medium hydrated solution for 3 days, then transferred non-treated medium, where they continued lay eggs. This procedure repeated obtain F2 generation. genotoxicity, somatic mutation recombination test (SMART) Comet assays performed. In these cases, higher chosen (1 20 50 mM). results showed that compound caused changes longevity prolificacy, also affected subsequent generations. They Drosophila’s social interaction, but exposure levels investigated here, did not significant genotoxic effects.

Язык: Английский

BIF-induced ROS-mediated cytotoxicity and genotoxicity in embryonic cell culture of Daphnia magna DOI

Sreevidya CP,

Vayampully Ajitha,

Manoj Kumar Tm

и другие.

Aquatic Toxicology, Год журнала: 2025, Номер 280, С. 107285 - 107285

Опубликована: Фев. 10, 2025

Язык: Английский

Процитировано

1
Design and optimization of a recirculating aquaculture system (RAS) for live feed production in aquaculture: a case study using Daphnia magna DOI

Chandrasekharan Parvathi Sreevidya,

Vayampully Ajitha,

Manoj Kumar T.M

и другие.

Aquaculture International, Год журнала: 2025, Номер 33(3)

Опубликована: Март 4, 2025

Язык: Английский

Процитировано

1
Biological and Behavioural Effects of Bisphenol A (BPA) Exposure: An In Vivo Study in Drosophila melanogaster DOI Creative Commons
Isabel Gaivão, Rita António Santos, Тетяна Морозова

и другие.

Applied Sciences, Год журнала: 2025, Номер 15(10), С. 5588 - 5588

Опубликована: Май 16, 2025

Bisphenol A (BPA) is one of the most produced compounds worldwide. It acts as an endocrine disruptor and can cause adverse effects in body, even at low-dose exposures. By interacting with estrogen receptors, it play important role pathogenesis several diseases, such infertility, hormone-dependent tumours various metabolic disorders. Exposure humans, especially early life, particular concern, since have a big impact on individual’s development growth. The objective this study was to evaluate, vivo, genotoxicity BPA its longevity, prolificacy behaviour Drosophila melanogaster. To evaluate biological behavioural effects, flies were crossed subjected different concentrations (0.5 mM, 1 2 5 mM 10 mM) instant “Carolina” medium hydrated solution for 3 days, then transferred non-treated medium, where they continued lay eggs. This procedure repeated obtain F2 generation. genotoxicity, somatic mutation recombination test (SMART) Comet assays performed. In these cases, higher chosen (1 20 50 mM). results showed that compound caused changes longevity prolificacy, also affected subsequent generations. They Drosophila’s social interaction, but exposure levels investigated here, did not significant genotoxic effects.

Язык: Английский

Процитировано

0