Ecology and Evolution,
Год журнала:
2024,
Номер
14(11)
Опубликована: Ноя. 1, 2024
Bats
exhibit
a
greater
capacity
to
tolerate
diverse
viruses
than
other
terrestrial
mammals.
To
address
these
questions,
we
utilized
evolutionary
and
bibliometric
analyses
explore
the
immunological
characteristics
of
bats
identify
contemporary
research
hotspots
in
bat
immunity.
investigate
historical
interactions
between
viral
infections,
used
tBLASTn
software
integrated
endogenous
retroviruses
within
genomes
nine
species
seven
elucidate
immune
bats,
OrthoFinder,
CAFE,
Gene
Ontology
phylogenetic
trees
homologous
genes,
expanded/contracted
gene
families,
associated
signaling
pathways
28
mammalian
genomes.
We
also
analysis
"immune
system
bats"
deepen
our
understanding
mechanisms
bats.
Significant
integrations
Gammaretroviruses,
Spumaretroviruses,
Deltaretroviruses
were
observed
Notable
expansions
families
included
Type
III
interferon,
heat-shock
protein
90
(HSP90),
members
tumor
necrosis
factor
receptor
superfamily
(TNFRSF).
These
expanded
are
involved
related
"transcription
replication
influenza
virus
RNA,"
"COVID-19-related
pathways,"
"positive
regulation
phosphorylation."
contractions
"type
I
interferon"
"antibody-related
families."
Bibliometric
further
underscored
several
significance
critical
such
as
HSP90,
TNF.
The
exploration
revealed
two
predominant
themes:
"efficient
varied
antiviral
responses"
"dampened
inflammation
prevent
excessive
inflammatory
reactions,"
thereby
elucidating
underlying
adaptations
Through
analyses,
identified
genes
Currently,
on
primarily
focuses
themes
"inflammation
suppression."
Healthcare,
Год журнала:
2024,
Номер
12(18), С. 1853 - 1853
Опубликована: Сен. 14, 2024
Background:
As
the
elderly
population
rapidly
grows,
age-related
health
issues
are
increasing.
Telemedicine
helps
older
adults
adapt
by
providing
efficient
and
accessible
management
medical
services.
Objectives:
This
study
employs
bibliometric
analysis
to
examine
research
focus
areas,
emerging
trends,
collaboration
networks
in
telemedicine
for
over
past
three
decades.
Methods:
The
Web
of
Science
Core
Collection
served
as
primary
data
source
publications
on
since
database’s
inception
through
June
2024.
Using
CiteSpace.6.2.R4
software,
keyword
network
visualizations
were
generated,
including
clusters,
co-authors,
co-citations.
Results:
analyzed
586
papers
from
252
countries
or
regions,
which
published
across
246
journals
written
2750
authors.
Conclusions:
revealed
directions
encompassing
42
clusters:
(1)
literacy
technology
adaptation;
(2)
management;
(3)
social
interaction
economic
impact.
Research
hotspots
include
fitness,
mobile
health,
acceptance,
telemedicine,
care,
literacy.
Despite
potential
benefit
challenges
persist
areas
such
usability,
effectiveness,
service
quality,
privacy
concerns.
review
provides
a
comprehensive
overview
current
highlights
trends
field.
World Journal of Gastroenterology,
Год журнала:
2024,
Номер
30(41), С. 4461 - 4480
Опубликована: Окт. 23, 2024
BACKGROUND
With
the
increasing
of
global
aging
population,
healthy
and
prevention
age-related
diseases
have
become
increasingly
important.
The
liver,
a
vital
organ
involved
in
metabolism,
detoxification,
digestion,
immunity,
holds
pivotal
role
process
organisms.
Although
extensive
research
on
liver
has
been
carried
out,
no
bibliometric
analysis
conducted
to
evaluate
scientific
progress
this
area.
AIM
To
analyze
basic
knowledge,
development
trends,
current
frontiers
field
via
methods.
METHODS
We
analyses
range
analytical
tools
including
Python,
bibliometrix
package
R,
CiteSpace,
VOSviewer.
retrieved
publication
data
from
Web
Science
Core
Collection
Database.
A
knowledge
map
was
constructed
display
contributions
different
authors,
journals,
countries,
institutions,
as
well
patterns
co-occurrence
keywords
co-cited
references.
Additionally,
gene
regulation
pathways
associated
with
were
analyzed
STRING
database.
RESULTS
identified
4288
articles
aging,
authored
by
24034
contributors
4092
institutions
across
85
countries.
Notably,
years
1991
2020
presented
significant
bursts
output.
United
States
led
terms
publications
(n
=
1008,
25.1%),
citations
55205),
international
collaborations
(multiple
country
214).
Keywords
such
“lipid
metabolism”,
“fatty
disease”,
“inflammation”,
“liver
fibrosis”
“target”
prominent,
highlighting
hotspots.
top
64
genes,
each
which
appeared
at
least
8
articles,
essential
for
cell
survival
phosphatidylinositol
3-kinase/protein
kinase
B,
Forkhead
box
O
p53
signaling
pathways.
CONCLUSION
This
study
highlights
key
areas
offers
comprehensive
overview
insights
into
potential
value
collaborative
pursuits
clinical
implementations.
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2023,
Номер
unknown
Опубликована: Дек. 7, 2023
Abstract
Background
Two
distinct
symptom
dimensions
were
identified
in
older
adults
who
did
not
have
major
depressive
disorder
(MDD):
a)
a
dimension
associated
with
mild
cognitive
dysfunction,
and
b)
related
to
distress
symptoms
of
old
age
(DSOA).
It
is
uncertain
whether
previous
findings
regarding
the
features
amnestic
impairment
(aMCI)
remain
valid
when
patients
MDD
are
excluded.
Objectives
To
examine,
participants
without
MDD,
neurocognitive
characteristics
aMCI
objective
DSOA.
Neurocognition
was
evaluated
utilizing
Cambridge
Neurological
Test
Automated
Battery
(CANTAB)
memory
tests.
Results
This
research
demonstrated
that
CANTAB
tests
capability
differentiate
between
controls.
The
One
Touch
Stockings
Cambridge,
probability
solved
on
first
choice
(OTS_PSFC),
Rapid
Visual
Information
Processing,
A
prime,
Motor
Screening
Task,
mean
latency
(MOT_ML),
as
significant
discriminatory
37.6%
variance
severity
predicted
by
OTS_PSFC,
RVP_A’,
word
list
recognition
scores,
education.
Psychosocial
stressors
(adverse
childhood
experiences,
negative
life
events),
subjective
feelings
impairment,
RVP,
false
alarm,
account
for
40.0%
DSOA
score.
Discussion
When
ruled
out,
linked
deficits
attention,
executive
functions,
memory.
statistically
impact
or
its
severity.
Enhanced
alarm
response
bias
coupled
heightened
psychological
stress
(including
perception
decline)
may
contribute
an
increase
among
elderly.
Keys
word:
depression,
adverse
stress,
anxiety
Ecology and Evolution,
Год журнала:
2024,
Номер
14(11)
Опубликована: Ноя. 1, 2024
Bats
exhibit
a
greater
capacity
to
tolerate
diverse
viruses
than
other
terrestrial
mammals.
To
address
these
questions,
we
utilized
evolutionary
and
bibliometric
analyses
explore
the
immunological
characteristics
of
bats
identify
contemporary
research
hotspots
in
bat
immunity.
investigate
historical
interactions
between
viral
infections,
used
tBLASTn
software
integrated
endogenous
retroviruses
within
genomes
nine
species
seven
elucidate
immune
bats,
OrthoFinder,
CAFE,
Gene
Ontology
phylogenetic
trees
homologous
genes,
expanded/contracted
gene
families,
associated
signaling
pathways
28
mammalian
genomes.
We
also
analysis
"immune
system
bats"
deepen
our
understanding
mechanisms
bats.
Significant
integrations
Gammaretroviruses,
Spumaretroviruses,
Deltaretroviruses
were
observed
Notable
expansions
families
included
Type
III
interferon,
heat-shock
protein
90
(HSP90),
members
tumor
necrosis
factor
receptor
superfamily
(TNFRSF).
These
expanded
are
involved
related
"transcription
replication
influenza
virus
RNA,"
"COVID-19-related
pathways,"
"positive
regulation
phosphorylation."
contractions
"type
I
interferon"
"antibody-related
families."
Bibliometric
further
underscored
several
significance
critical
such
as
HSP90,
TNF.
The
exploration
revealed
two
predominant
themes:
"efficient
varied
antiviral
responses"
"dampened
inflammation
prevent
excessive
inflammatory
reactions,"
thereby
elucidating
underlying
adaptations
Through
analyses,
identified
genes
Currently,
on
primarily
focuses
themes
"inflammation
suppression."
