On the merits and potential of advanced neuroimaging techniques in COVID-19: A scoping review DOI Creative Commons
Noa van der Knaap, Marcel Aries, Iwan C.C. van der Horst

и другие.

NeuroImage Clinical, Год журнала: 2024, Номер 42, С. 103589 - 103589

Опубликована: Янв. 1, 2024

Many Coronavirus Disease 2019 (COVID-19) patients are suffering from long-term neuropsychological sequelae. These may benefit a better understanding of the underlying neuropathophysiological mechanisms and identification potential biomarkers treatment targets. Structural clinical neuroimaging techniques have limited ability to visualize subtle cerebral abnormalities investigate brain function. This scoping review assesses merits advanced in COVID-19 using literature including or postmortem analyses adult published start pandemic until December 2023. Findings were summarized according distinct categories reported revealed by different imaging techniques. Although no unified COVID-19-specific pattern could be subtracted, broad range (likely attributable hypoxic, vascular, inflammatory pathology), even absence structural findings. validated examinations. emphasizes added value compared highlights implications for functioning consequences COVID-19.

Язык: Английский

Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations DOI Creative Commons
Leonie Kausel, Alejandra Figueroa-Vargas, Francisco Zamorano

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Авг. 17, 2024

Patients recovering from COVID-19 commonly exhibit cognitive and brain alterations, yet the specific neuropathological mechanisms risk factors underlying these alterations remain elusive. Given significant global incidence of COVID-19, identifying that can distinguish individuals at developing is crucial for prioritizing follow-up care. Here, we report findings a sample patients consisting 73 adults with mild to moderate SARS-CoV-2 infection without signs respiratory failure 27 infections attributed other agents no history COVID-19. The participants underwent screening, decision-making task, MRI evaluations. We assessed presence anosmia requirement hospitalization. Groups did not differ in age or performance. who presented exhibited more impulsive alternative changes after shift probabilities (r = − 0.26, p 0.001), while required hospitalization showed perseverative choices 0.25, 0.003). Anosmia correlated measures, including decreased functional activity during thinning cortical thickness parietal regions, loss white matter integrity. Hence, could be factor considered when at-risk populations follow-up.

Язык: Английский

Процитировано

8
On the merits and potential of advanced neuroimaging techniques in COVID-19: A scoping review DOI Creative Commons
Noa van der Knaap, Marcel Aries, Iwan C.C. van der Horst

и другие.

NeuroImage Clinical, Год журнала: 2024, Номер 42, С. 103589 - 103589

Опубликована: Янв. 1, 2024

Many Coronavirus Disease 2019 (COVID-19) patients are suffering from long-term neuropsychological sequelae. These may benefit a better understanding of the underlying neuropathophysiological mechanisms and identification potential biomarkers treatment targets. Structural clinical neuroimaging techniques have limited ability to visualize subtle cerebral abnormalities investigate brain function. This scoping review assesses merits advanced in COVID-19 using literature including or postmortem analyses adult published start pandemic until December 2023. Findings were summarized according distinct categories reported revealed by different imaging techniques. Although no unified COVID-19-specific pattern could be subtracted, broad range (likely attributable hypoxic, vascular, inflammatory pathology), even absence structural findings. validated examinations. emphasizes added value compared highlights implications for functioning consequences COVID-19.

Язык: Английский

Процитировано

4