Deciphering the mechanisms, hormonal signaling, and potential applications of endophytic microbes to mediate stress tolerance in medicinal plants

Frontiers in Plant Science, Год журнала: 2023, Номер 14

Опубликована: Ноя. 15, 2023

The global healthcare market in the post-pandemic era emphasizes a constant pursuit of therapeutic, adaptogenic, and immune booster drugs. Medicinal plants are only natural resource to meet this by supplying an array bioactive secondary metabolites economic, greener sustainable manner. Driven thrust demand for immunity imparting nutraceutical life-saving plant-derived drugs, acreage commercial cultivation medicinal has dramatically increased recent years. Limited resources land water, low productivity, poor soil fertility coupled with climate change, biotic (bacteria, fungi, insects, viruses, nematodes) abiotic (temperature, drought, salinity, waterlogging, metal toxicity) stress necessitate plant productivity enhancement through strategies. Plants evolved intricate physiological (membrane integrity, organelle structural changes, osmotic adjustments, cell tissue survival, reclamation, root-shoot ratio, antibiosis, hypersensitivity, etc.), biochemical (phytohormones synthesis, proline, protein levels, antioxidant enzymes accumulation, ion exclusion, generation heat-shock proteins, synthesis allelochemicals. cellular (sensing signals, signaling pathways, modulating expression stress-responsive genes etc.) mechanisms combat stresses. Endophytes, colonizing different tissues, synthesize novel compounds that can harness mitigate environmental cues, thus making agroecosystems self-sufficient toward green approaches. host set endophytes another interact highly complex manner involving adaptive mechanisms, including appropriate responses triggered stimuli received from sensors situated on cytoplasm transmitting signals transcriptional machinery nucleus withstand stressful environment effectively. Signaling pathways serve as crucial nexus sensing establishing plants’ proper molecular responses. However, underlying critical endophytic microbes meager. This review comprehends diversity endophyte-mediated plant-microbe interactions tolerance understanding cascades defined Leveraging knowledge, researchers design specific microbial formulations optimize health, increase nutrient uptake, boost crop yields, support resilient, agricultural system.

Язык: Английский

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Bioprospecting of endophytic fungi from medicinal plant Anisomeles indica L. for their diverse role in agricultural and industrial sectors

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Янв. 5, 2024

Abstract Endophytes are microorganisms that inhabit various plant parts and cause no damage to the host plants. During last few years, a number of novel endophytic fungi have been isolated identified from medicinal plants were found be utilized as bio-stimulants bio fertilizers. In lieu this , present study aims isolate identify associated with leaves Anisomeles indica L. an important Terai-Duars region West Bengal. A total ten A. five using ITS1/ITS4 sequencing based on their ability for growth promotion, secondary metabolite production, extracellular enzyme production. Endophytic fungal isolates Colletotrichum yulongense Ai1, cobbittiense Ai2, alienum Ai2.1, Ai3, Fusarium equiseti . Five tested positive promotion potential, while Ai4. Ai2.1 showed significant production metabolites viz. alkaloids, phenolics, flavonoids, saponins, etc. Isolate Ai2 maximum phenolic concentration (25.98 mg g −1 ), Ai4 flavonoid (20.10 ). Significant results observed enzymes such cellulases, amylases, laccases, lipases, The significantly influenced seed germination percentage tomato seedlings augmented development under in vitro assay. work comprehensively these ascertained huge application commercial utilization both agricultural industrial sectors.

Язык: Английский

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Synergistic partnerships of endophytic fungi for bioactive compound production and biotic stress management in medicinal plants

Plant Stress, Год журнала: 2024, Номер 11, С. 100425 - 100425

Опубликована: Март 1, 2024

The fungal endophytes are an understudied area of research with great potential for new bioactive compounds' discovery. These the strains that live within inner compartments host plant without causing it any kind harm. endophytes, in combination organisms, synthesize many compounds a range pharmaceutical values. Most recently, discovery endophyte genes which linked biosynthesis metabolites has opened field research. partners assist plants against biotic stress and protect them from pathogenic attacks or diseases presence some important gene families like WRKY MYB. this group known their anticancer, antimicrobial, antioxidant, antidiabetic, anti-tubercular properties. Therefore, these offer routes discovering novel drugs, can boost industry times demand drugs. Extracellular enzymes also produced members distinct crucial several industrial sectors, including biofuel production industry. Furthermore, capable synthesizing silver nanoparticles, exhibit significant fields biomedical imaging water purification. This article aims to document all available data on fungi living medicinal major by use therapy various ailments.

Язык: Английский

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Chitinases: expanding the boundaries of knowledge beyond routinized chitin degradation.

Environmental Science and Pollution Research, Год журнала: 2024, Номер 31(26), С. 38045 - 38060

Опубликована: Май 24, 2024

Abstract Chitinases, enzymes that degrade chitin, have long been studied for their role in various biological processes. They play crucial roles the moulting process of invertebrates, digestion chitinous food, and defense against chitin-bearing pathogens. Additionally, chitinases are involved physiological functions crustaceans, such as food digestion, moulting, stress response. Moreover, universally distributed organisms from viruses to mammals diverse including tissue degradation remodeling, nutrition uptake, pathogen invasion, immune response regulation. The discovery these expands our understanding significance potential applications chitinases. However, recent research has shown possess several other beyond just chitin degradation. Their biopesticides, therapeutic agents, tools bioremediation underscores addressing global challenges. More importantly, we noted they may be applied bioweapons if ethical regulations regarding production, engineering application overlooked.

Язык: Английский

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Fungal endophytes from medicinal plants acting as natural therapeutic reservoir

The Microbe, Год журнала: 2024, Номер 3, С. 100073 - 100073

Опубликована: Апрель 22, 2024

Fungal endophytes are reservoirs of bioactive molecules that impart therapeutic potential to indigenous medicinal plants. Since new strains microbial pathogens evolving with their ability towards drug resistance, herbal phytometabolites a lead for exploiting in the field medicine. The ethnobotanical literature and scientific plants traditional medicine have always developed interest piqued compounds produced by endophytic bacteria fungi. association imparts attributes plant metabolites. Endophytes include bacteria, viruses, fungi, but as per literature, fungal more promising exploring compounds, they synthesize host occurrence associations is found almost all species, roles well established. This present roots, stems, leaves, these enhance growth, yield, stress tolerance, control pathogens, manage diseases naturally. In review, benefits such anti-inflammatory, antimicrobial, anticancer, antidepressants, immunosuppressant, etc. discussed.

Язык: Английский

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Multifunctional Efficacy and Eco-friendly Applications of Fungal Endophytes

Опубликована: Янв. 1, 2025

Язык: Английский

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Isolation of endophytes from Dioscorea nipponica Makino for stimulating diosgenin production and plant growth

Plant Cell Reports, Год журнала: 2024, Номер 43(4)

Опубликована: Март 12, 2024

Язык: Английский

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A systematic review on ethnobotany, phytochemistry and pharmacology of Dioscorea bulbifera L. (Dioscoreaceae)

South African Journal of Botany, Год журнала: 2024, Номер 170, С. 367 - 393

Опубликована: Июнь 1, 2024

Язык: Английский

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Genome Sequence and Characterisation of Peribacillus sp. Strain AS_2, a Bacterial Endophyte Isolated from Alectra sessiliflora

Microbiology Research, Год журнала: 2023, Номер 15(1), С. 50 - 65

Опубликована: Дек. 21, 2023

Peribacillus sp. AS_2, a leaf endophytic bacterium isolated from the medicinal plant Alectra sessiliflora, was previously identified using 16S rRNA gene sequence. The draft genome of AS_2 had 5,482,853 bp circular chromosome, 43 contigs, N50 360,633 and an average G + C% content 40.5%. Whole sequencing phenotypic analysis showed that Gram-positive, endospore-forming, motile, rod-shaped it high sequence similarity with P. frigoritolerans DSM 8801T. Genomic digital DNA–DNA hybridisation (dDDH) between strain 8801T castrilensis N3T 84.8% 79.2%, respectively, nucleotide identity (ANI) 97.0% 96.7%, respectively. antiSMASH software predicted total eight secondary metabolite clusters comprising non-ribosomal peptide synthetase (NRPS) type koranimine, terpenes, siderophore clusters. Strain also displayed genes involved in lifestyle antibiotic resistance such as small multidrug efflux pumps (qacJs). Using multilocus (MLSA), together data genomic analysis, we demonstrated is subspecies Genome plants provides valuable information allows us to further explore its biotechnological applications.

Язык: Английский

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Insights into the culturable fungal endophytes of Dioscorea bulbifera L. in terms of their diversity, antidiabetic and antioxidant activity

South African Journal of Botany, Год журнала: 2024, Номер 174, С. 593 - 605

Опубликована: Сен. 27, 2024

Язык: Английский

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