Abstract
Salinity
is
among
the
major
abiotic
stresses
faced
by
different
countries;
limiting
plant
growth,
development
and
yield.
This
research
work
was
carried
out
to
evaluate
influence
of
green
prepared
titanium
dioxide
nanoparticles
(TiO
2
NPs)
on
metabolic
constituents
ultrastructural
alterations
soybean
(
Glycine
max
L.)
plants
exposed
salt
stress.
TiO
NPs
were
synthesized
using
an
aqueous
solution
Aloe
vera
leaf
extract
obtained
identified
several
techniques.
An
in
vivo
pot
experiment
role
foliar
sprayed
(30
ppm)
irrigated
six
NaCl
concentrations
(0,
25,
50,
100,
150
200
mM).
After
15
30
days
from
application,
growth
parameters,
photosynthetic
pigments,
total
soluble
protein,
enzymatic
antioxidants
changes
tested
for
potential
tolerance
growing
under
Results
revealed
that
increasing
induced
a
significant
decrease
shoot
length,
fresh
dry
weights
as
well
these
decreases
due
electrolyte
leakage
plants.
However,
application
showed
improvements
vegetative
its
pigments
protein
contents.
There
marked
increase
contents
stressed
further
accumulation
their
with
application.
Salt
structural
deformation
which
lessened
Finally,
our
demonstrates
alleviating
stress
via
restoring
cell
ultrastructure,
highlighting
sustainable
eco-friendly
strategy.
Green
resource
synthesis
is
a
sustainable,
economical,
and
environmentally
benign
process
that
produces
no
pollutants.
Plant-based
nanoparticles
have
lower
toxicity
level.
Because
aloe
vera
contains
bioactive
chemicals
such
flavonoids,
phenol,
alkaloids,
saponins,
others,
it
can
operate
as
reducing
agent
to
reduce
metal
ions.
As
agents,
these
substances
are
therefore
essential
the
formation
of
nanoparticles.
When
heated,
they
transform
into
corresponding
oxides.
This
article
describes
tin
(IV)
oxide
using
gel
their
structural
characteristics.
The
antibacterial
ability
produced
was
then
evaluated
by
testing
them
against
Gram-positive
bacteria
like
Bacillus
cereus
Staphylococcus
aureus
well
Gram-negative
Shigella
flexneri,
Salmonella
typhi,
Escherichia
coli.
study
shows
effectiveness
dependability
green
techniques
use
Aloe
rather
than
chemical-based
approaches
been
used
up
this
point
create
It
less
likely
fail
has
high
biological
activity.
Thus,
precious
for
applications
in
environmental
healthcare
fields
industries.
highlights
advantages
developing
sustainable
materials
through
routes
wide
range
applications.
Critical Reviews in Analytical Chemistry,
Год журнала:
2025,
Номер
unknown, С. 1 - 20
Опубликована: Май 15, 2025
Gold
Nanoparticles
(GNPs)
play
a
pivotal
role
in
nanobiotechnology
because
of
their
distinct
physicochemical
traits,
such
as
optical
properties,
compatibility
with
biological
systems,
and
ability
to
be
easily
functionalized.
The
top-down
bottom-up
approaches
are
for
the
synthesis
GNPs.
There
various
chemical,
physical,
green
techniques,
chemical
reduction,
seed-mediated
growth,
physical
ablation
method,
pyrolysis,
sputtering,
etc.
some
methods
use
plants,
algae,
fungi,
other
microorganisms
has
recently
arisen
new
approach
eco-friendly
precise
control
over
NP
size,
shape,
surface
properties.
functionalization
strategies
involving
biomolecules,
polymers,
ligands
enhance
stability
target
specificity,
facilitating
integration
into
biosensors.
detection
pathogens,
environmental
toxins
high
sensitivity
accuracy
is
facilitated
by
multiple
signals
localized
plasmon
resonance
(LSPR),
alterations
color,
electrochemical
characteristics.
Furthermore,
point-of-care
diagnostics,
drug
delivery,
imaging
underscores
versatility
biomedical
applications.
This
review
provides
comprehensive
overview
recent
advancements
synthesis,
functionalization,
GNPs-based
In
addition,
highlights
advancements,
challenges,
future
prospects
GNPs
biosensing
nanomedicine,
offering
an
understanding
diagnostics
therapeutic
monitoring.
key
challenges
include
stability,
reproducibility,
scalability,
focuses
on
enhanced
multiplexed
Acta Pharmaceutica,
Год журнала:
2025,
Номер
unknown
Опубликована: Июнь 4, 2025
Abstract
Aloe
vera
has
a
long
history
of
medicinal
use
due
to
its
diverse
biological
activities,
including
antioxidant,
anti-inflammatory
and
antimicrobial.
This
study
investigates
the
physicochemical
ADME
(absorption,
distribution,
metabolism,
excretion)
properties
two
primary
anthraquinones
from
,
aloin
A
aloe-emodin.
The
focus
this
research
was
evaluate
lipophilicity,
solubility,
pharmacokinetic
profiles
aloe-emodin
through
combination
computational
predictions,
shake-flask
method,
chromatographic
techniques.
optimised
method
successfully
employed
determine
log
P
values
phyto-chemicals.
Aloin
found
be
more
hydrophilic
than
aloe-emodin,
likely
presence
an
attached
β-d-glucopyranosyl
unit.
All
RP-TLC
RP-HPLC
lipophilicity
indices
were
higher
for
compared
A,
aligning
with
their
(obtained
in
silico
methods).
IAM
(immobili
sed
artificial
membrane)-HPLC
results
suggest
that
unlikely
partitioning
n
-octanol/water
system
or
C18
chains,
partition
into
phospholipids
involves
not
only
hydrophobic
intermolecular
recognition
forces
but
also
electrostatic
interactions.
sugar
moiety
(β-d-glucopyranosyl
unit)
at
C-10
position
considerably
enhanced
affinity
alkyl
chains.
HSA
(human
serum
albumin)-HPLC
AGP
(α1-acid
glycoprotein)-HPLC
data
confirmed
aloe-emodin’s
stronger
plasma
proteins.
integration
experimental
approaches
provided
detailed
understanding
properties.
