Medical Oncology, Год журнала: 2025, Номер 42(4)
Опубликована: Март 18, 2025
Язык: Английский
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Янв. 3, 2025
Nanomedical applications have increased significantly. This work aimed to fabricate and characterize cobalt oxide nanoparticles (CoOnps) synthesized biologically via aqueous Alhagi maurorum extract evaluate their cytotoxic antimicrobial impacts. Green-synthesized CoOnps were prepared analyzed using UV–Vis spectrophotometer UV–vis, Scanning electron microscopy (SEM), Transmission TEM, Energy dispersive X-ray analysis EDAX, Fourier transform infrared, FTIR, diffraction (XRD). In vitro traits of green-synthesized studied on ovarian cancer cells (SKOV3) a Sulforhodamine B (SRB) method. The effect IC50 estimated. Moreover, concentrations 10, 30, 40, 70, 100, 200, 300, 400 500 μg/mL applied investigate against Listeria, Staphylococcus aureus Streptococcus as gram +ve pathogenic bacteria, Bifidobacterium bifidum 2203, LMG 10,645, breve LMC 017, angulatum 2238 longum ATCC 15,707 probiotics, E. coli −ve bacterial model yeast strain Candida albicans. showed anti-ovarian effects at 24.02 μg/mL. Furthermore, it exerted activity versus Streptococcus, S. aureus, 31.66 ± 0.88, 24.33 2.08, 25.66 0.33, 33.00 6.08; however, they did not suppress the growth albicans all tested Bifidobacterial strains up with significant difference compared p < 0.05. Green synthesis is low-cost, eco-friendly easily Its impressive features SKOV3, cell line antibacterial for some besides maintaining could candidate them competitive agents medical, pharmacological, agricultural food applications.
Язык: Английский
Процитировано
2
OpenNano, Год журнала: 2024, Номер 20, С. 100213 - 100213
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
12
Pharmaceutics, Год журнала: 2024, Номер 16(9), С. 1232 - 1232
Опубликована: Сен. 21, 2024
Silver nanoparticles (AgNPs) are leading the way in nanotechnological innovation, combining captivating properties of silver with accuracy nanoscale engineering, thus revolutionizing material science. Three main techniques arise within alchemical domains AgNP genesis: chemical, physical, and biological synthesis. Each possesses its distinct form magic for controlling size, shape, scalability—key factors necessary achieving expertise practical application nanoparticles. The story unravels, describing careful coordination chemical reduction, environmentally sensitive charm green synthesis utilizing plant extracts, precise physical techniques. AgNPs highly praised field healthcare their powerful antibacterial characteristics. These little warriors display a wide-ranging attack against bacteria, fungi, parasites, viruses. Their critical significance combating hospital-acquired surgical site infections is praised, serving as beacon hope fight challenging problem antibiotic resistance. In addition to ability kill also known promote tissue regeneration facilitate wound healing. cancer has observed adaptability AgNPs. review documents role innovative carriers drugs, specifically designed target cells accuracy, minimizing harm healthy tissues. Additionally, it explores potential therapy or anticancer agents capable disrupting growth tumors. food business, utilized enhance durability packing materials coatings by infusing them bactericidal properties. This results improved safety measures significant increase duration that products can be stored, thereby tackling crucial issue preservation. academic analysis recognizes many difficulties come creation incorporation statement pertains evaluation environmental effort synthetic processes. predicts future pursuits, envisioning progress will usefulness importance from being new becoming essential realms science industry. Besides, not only subject scholarly interest but component continuous tackle some most urgent health conservation concerns contemporary society. aims explore complex process highlight numerous uses, special focus on growing business sectors. invites scientific community extensive possibilities order fully understand utilize potential.
Язык: Английский
Процитировано
10
Nanomaterials, Год журнала: 2024, Номер 14(20), С. 1618 - 1618
Опубликована: Окт. 10, 2024
Silver nanoparticles (NPs) have become highly promising agents in the field of biomedical science, offering wide therapeutic potential due to their unique physicochemical properties. The characteristics silver NPs, such as higher surface-area-to-volume ratio, make them ideal for a variety biological applications. They are easily processed thanks large surface area, strong plasmon resonance (SPR), stable nature, and multifunctionality. With an emphasis on mechanisms action, efficacy, prospective advantages this review attempts give thorough overview numerous applications these particles. utilization NPs diagnostics, bioimaging biosensing, well functions interventions antimicrobial therapies, cancer therapy, diabetes treatment, bone repair, wound healing, investigated. underlying processes by which exercise effects, oxidative stress induction, apoptosis, microbial cell membrane rupture, explored. Furthermore, toxicological concerns regulatory issues discussed, present difficulties restrictions related application medicine.
Язык: Английский
Процитировано
10
Green Processing and Synthesis, Год журнала: 2025, Номер 14(1)
Опубликована: Янв. 1, 2025
Abstract This study optimizes the green synthesis of silver nanoparticles (AgNPs) using seed skin extract guarana ( Paullinia cupana ) as a natural stabilizing and reducing agent. Employing Taguchi design, nine experiments were conducted across three levels for four key factors: reaction temperature, pH, nitrate concentration, concentration to minimize AgNP size. Optimal conditions – pH 11, 5 mM nitrate, 50°C 1% (m/v) produced quasi-spherical AgNPs with an average size ∼26 nm. Chemical analysis revealed caffeine main organic compound potassium oxide primary inorganic component. UV-vis spectra showed absorption peak at 438 nm, X-ray diffraction confirmed typical peaks. Further identified polyphenols, alkaloids, flavonoids agents. A high (180.0 ± 0.2 ppm) was through ICP-OES, demonstrated significant antibacterial activity against Escherichia coli Staphylococcus aureus , minimum inhibitory 50 μg·mL −1 . underscores sustainability promising alternative traditional nanoparticle production methods.
Язык: Английский
Процитировано
1
Journal of Photochemistry and Photobiology B Biology, Год журнала: 2025, Номер 263, С. 113102 - 113102
Опубликована: Янв. 18, 2025
Язык: Английский
Процитировано
1
Journal of environmental chemical engineering, Год журнала: 2025, Номер unknown, С. 115998 - 115998
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1
Medical Oncology, Год журнала: 2025, Номер 42(4)
Опубликована: Март 17, 2025
Язык: Английский
Процитировано
1
Biomass Conversion and Biorefinery, Год журнала: 2024, Номер unknown
Опубликована: Июнь 23, 2024
Язык: Английский
Процитировано
6
Microscopy Research and Technique, Год журнала: 2024, Номер 87(9), С. 2121 - 2133
Опубликована: Май 5, 2024
Abstract The present study incorporated an environment‐friendly and cost‐efficient green synthesis method for fabricating zinc oxide nanoparticles (ZnO‐NPs) using various parts (leaves, buds, flowers) of Bauhinia Variegate Linn. UV‐Spectrophotometric analysis was used to confirm the ZnO‐NPs, which showed absorption band within 360–380 nm range. Further techniques like FT‐IR spectroscopy (SEM) scanning electron microscopy equipped with a novel EDX were also included synthesis, size, shape ZnO‐NPs. Results obtained by that phytochemicals in ethanolic extract successfully acted as capping agent. SEM micrographs confirmed irregularly shaped average size 70–80 nm. presence Zinc Oxygen peaks successful ZnO nanoparticles. radical scavenging (antioxidant) potential prepared evaluated DPPH assay. ZnO‐NPs from buds highest %RSA (86%) compared flowers (79%) leaves (76%). current findings versatile morphology all plant significant antioxidant potential, establishing use biological systems biomedical applications. Research Highlights A thorough comparative power major , is 1st its kind. Extensive characterization UV–Vis spectrophotometry, FT‐IR, SEM, observe conformational morphological changes. Analysis reduction leaves, single future directions synthesis.
Язык: Английский
Процитировано
5