Antibacterial Properties of Polymeric Membranes Containing Doxycycline for Potential Applications in Foot Ulcer Treatment DOI Open Access

Stevaly Pérez-Gutiérrez,

Jesús Ángel Ramírez-Enciso,

Laura Abisaí Pazos-Rojas

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 3274 - 3274

Опубликована: Апрель 1, 2025

Membranes made from biopolymers and loaded with doxycycline were investigated for potential use in the treatment of foot ulcers diabetic patients. Carboxymethylcellulose (CMC) chitosan (CHS) membranes fabricated 7% glycerol 1% (DOX). Their mechanical physical properties, biocompatibility, antimicrobial effects thoroughly evaluated. The results demonstrated effective antibacterial activity against S. aureus mutans. Based on mechanical, physical, hemolytic data, DOX-loaded CMC/CHS/G show promise as a topical wound delivery system.

Язык: Английский

Antibacterial Properties of Polymeric Membranes Containing Doxycycline for Potential Applications in Foot Ulcer Treatment DOI Open Access

Stevaly Pérez-Gutiérrez,

Jesús Ángel Ramírez-Enciso,

Laura Abisaí Pazos-Rojas

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 3274 - 3274

Опубликована: Апрель 1, 2025

Membranes made from biopolymers and loaded with doxycycline were investigated for potential use in the treatment of foot ulcers diabetic patients. Carboxymethylcellulose (CMC) chitosan (CHS) membranes fabricated 7% glycerol 1% (DOX). Their mechanical physical properties, biocompatibility, antimicrobial effects thoroughly evaluated. The results demonstrated effective antibacterial activity against S. aureus mutans. Based on mechanical, physical, hemolytic data, DOX-loaded CMC/CHS/G show promise as a topical wound delivery system.

Язык: Английский

Процитировано

0