Tissue
repair
and
regeneration
are
critical
processes
for
maintaining
the
integrity
function
of
various
organs
tissues.
Recently,
polysaccharide
materials
protein
have
garnered
interest
use
in
tissue
strategies.
However,
polysaccharides
more
stable
unaffected
by
temperature
pH
changes
compared
to
proteins,
some
can
provide
stronger
mechanical
support,
which
is
particularly
important
constructing
tissue-engineered
scaffolds
wound
dressings.
This
Review
provides
an
in-depth
overview
origins
polysaccharides,
advantages
materials,
processing
design
In
addition,
potential
restoration
tissues
such
as
skin,
heart,
nerves
highlighted.
Finally,
we
discuss
depth
challenges
that
still
face
repair,
stability
material,
regulating
characteristics
deterioration
rates
under
different
conditions.
To
achieve
effective
regeneration,
future
research
must
focus
on
further
improving
functionalities
materials.
International Journal of Biological Macromolecules,
Год журнала:
2023,
Номер
251, С. 126287 - 126287
Опубликована: Авг. 11, 2023
Cellulose
nanocrystals
(CNCs)
have
gained
significant
attraction
from
both
industrial
and
academic
sectors,
thanks
to
their
biodegradability,
non-toxicity,
renewability
with
remarkable
mechanical
characteristics.
Desirable
characteristics
of
CNCs
include
high
stiffness,
strength,
excellent
flexibility,
large
surface-to-volume
ratio.
Additionally,
the
properties
can
be
tailored
through
chemical
modifications
for
high-end
applications
including
tissue
engineering,
actuating,
biomedical.
Modern
manufacturing
methods
3D/4D
printing
are
highly
advantageous
developing
sophisticated
intricate
geometries.
This
review
highlights
major
developments
additive
manufactured
CNCs,
which
promote
sustainable
solutions
across
a
wide
range
applications.
this
contribution
also
presents
current
challenges
future
research
directions
CNC-based
composites
developed
techniques
myriad
engineering
sectors
wound
healing,
wearable
electronics,
robotics,
anti-counterfeiting
Overall,
will
greatly
help
scientists
chemistry,
materials,
biomedicine,
other
disciplines
comprehend
underlying
principles,
properties,
additively
structures.
Abstract
Osteosarcoma
(OS)
is
distinguished
as
a
high-grade
malignant
tumor,
characterized
by
rapid
systemic
metastasis,
particularly
to
the
lungs,
resulting
in
very
low
survival
rates.
Understanding
complexities
of
tumor
development
and
mutation
need
hour
for
advancement
targeted
therapies
cancer
care.
A
significant
innovation
this
area
use
nanotechnology,
specifically
nanoparticles,
tackle
various
challenges
treatment.
Iron
oxide
nanoparticles
stand
out
both
therapeutic
diagnostic
applications,
offering
versatile
platform
drug
delivery,
hyperthermia,
magneto-thermal
therapy,
combinational
therapy
using
modulation
ferroptosis
pathways.
These
are
easy
synthesize,
non-toxic,
biocompatible,
display
enhanced
circulation
time
within
system.
They
can
also
be
easily
conjugated
anti-cancer
drugs,
targeting
agents,
or
genetic
vectors
that
respond
specific
stimuli
pH
changes.
The
surface
functionalization
these
bioactive
molecules
unveils
promising
effective
nanoparticle
system
assisting
osteosarcoma
therapy.
This
review
will
summarize
current
conventional
their
disadvantages,
synthesis
modification
iron
documented
literature,
cellular
uptake
mechanism,
with
focus
on
natural
biomaterials
application
strategies
towards
management
osteosarcoma.
compiles
translational
future
prospects
must
addressed
clinical
advancements
based
treatment
future.
Graphical
abstract
Polymers,
Год журнала:
2022,
Номер
14(19), С. 4189 - 4189
Опубликована: Окт. 6, 2022
Polysaccharides
constitute
one
of
the
most
important
families
biopolymers.
Natural
polysaccharide-based
drug
delivery
systems
are
constant
interest
to
scientific
community
due
their
unique
properties:
biocompatibility,
non-toxicity,
biodegradability,
and
high
availability.
These
promising
biomaterials
protect
sensitive
active
agents
provide
controlled
release
in
targeted
sites.
The
application
natural
polysaccharides
as
is
also
intensively
developed
by
Polish
scientists.
present
review
focuses
on
case
studies
from
last
few
years
authored
or
co-authored
research
centers
Poland.
A
particular
emphasis
was
placed
diversity
formulations
terms
substance
carried,
route,
composition
material,
its
preparation
method.
Polymers,
Год журнала:
2022,
Номер
14(18), С. 3791 - 3791
Опубликована: Сен. 10, 2022
This
review’s
objectives
are
to
provide
an
overview
of
the
various
kinds
biopolymer
hydrogels
that
currently
used
for
bone
tissue
and
periodontal
regeneration,
list
advantages
disadvantages
using
them,
assess
how
well
they
might
be
nanoscale
fabrication
biofunctionalization,
describe
their
production
processes
functionalization
with
active
biomolecules.
They
applied
in
conjunction
other
materials
(such
as
microparticles
(MPs)
nanoparticles
(NPs))
novel
techniques
replicate
physiological
generation
more
faithfully.
Enhancing
biocompatibility
created
from
blends
natural
synthetic
biopolymers
can
result
creation
best
scaffold
match
extracellular
matrix
(ECM)
regeneration.
Additionally,
adding
increase
hydrogel
stability
a
number
biological
effects.
In
this
review,
research
study
polysaccharide
will
critical
creating
valuable
effective
future
impact
predicted
repairing
defects.
Water
pollution
is
a
significant
environmental
issue
that
has
emerged
because
of
industrial
and
economic
growth.
Human
activities
such
as
industrial,
agricultural,
technological
practices
have
increased
the
levels
pollutants
in
environment,
causing
harm
to
both
environment
public
health.
Dyes
heavy
metals
are
major
contributors
water
pollution.
Organic
dyes
concern
their
stability
potential
absorb
sunlight,
increasing
temperature
disrupting
ecological
balance.
The
presence
production
textile
adds
toxicity
wastewater.
Heavy
global
can
human
health
mainly
caused
by
urbanization
industrialization.
To
address
this
issue,
researchers
focused
on
developing
effective
treatment
procedures,
including
adsorption,
precipitation,
filtration.
Among
these
methods,
adsorption
simple,
efficient,
cheap
method
for
removing
organic
from
water.
Aerogels
shown
promising
adsorbent
material
low
density,
high
porosity,
surface
area,
thermal
electrical
conductivity,
ability
respond
external
stimuli.
Biomaterials
cellulose,
starch,
chitosan,
chitin,
carrageenan,
graphene
been
extensively
studied
sustainable
aerogels
treatment.
Cellulose,
which
abundant
nature,
received
attention
recent
years.
This
review
highlights
cellulose-based
efficient
during
process.
