Recent Applications of Chitosan and Its Derivatives in Antibacterial, Anticancer, Wound Healing, and Tissue Engineering Fields

Polymers, Год журнала: 2024, Номер 16(10), С. 1351 - 1351

Опубликована: Май 10, 2024

Chitosan, a versatile biopolymer derived from chitin, has garnered significant attention in various biomedical applications due to its unique properties, such as biocompatibility, biodegradability, and mucoadhesiveness. This review provides an overview of the diverse chitosan derivatives antibacterial, anticancer, wound healing, tissue engineering fields. In antibacterial applications, exhibits potent antimicrobial properties by disrupting microbial membranes DNA, making it promising natural preservative agent against bacterial infections. Its role cancer therapy involves development chitosan-based nanocarriers for targeted drug delivery, enhancing therapeutic efficacy while minimising side effects. Chitosan also plays crucial healing promoting cell proliferation, angiogenesis, regulating inflammatory responses. Additionally, serves multifunctional scaffold engineering, facilitating regeneration tissues cartilage, bone, neural adhesion proliferation. The extensive range pharmaceutical sciences is not only highlighted comprehensive scope this review, but establishes fundamental component forthcoming research biomedicine.

Язык: Английский

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Opportunities and challenges of nanomaterials in wound healing: Advances, mechanisms, and perspectives

Chemical Engineering Journal, Год журнала: 2024, Номер 495, С. 153640 - 153640

Опубликована: Июль 1, 2024

Язык: Английский

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Chitosan‐Based Hydrogels as Antibacterial/Antioxidant/Anti‐Inflammation Multifunctional Dressings for Chronic Wound Healing

Advanced Healthcare Materials, Год журнала: 2024, Номер 13(30)

Опубликована: Июль 22, 2024

Abstract Due to repeated microbial infection, persistent inflammation, excessive oxidative stress, and cell dysfunction, chronic wounds are difficult heal, posing a serious threat public health. Therefore, developing multifunctional wound dressings that can regulate the complex microenvironment of enhance cellular function holds great significance. Recently, chitosan has emerged as promising biopolymer for healing due its excellent biocompatibility, biodegradability, versatile bioactivity. The aim this review is provide comprehensive understanding mechanisms delayed discuss healing–promoting properties derivatives, such good antibacterial activity, hemostatic capacity, ability promote tissue regeneration. On basis, potential applications chitosan‐based hydrogels summarized in healing, including providing suitable microenvironment, eliminating bacterial infections, promoting hemostasis, inhibiting alleviating In addition, concerns perspectives clinical application also discussed.

Язык: Английский

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Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study

ACS Omega, Год журнала: 2025, Номер 10(1), С. 1207 - 1225

Опубликована: Янв. 3, 2025

Manufacturing bioactive materials for drug delivery involves developing that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is optimize therapeutic efficacy reduce side effects by combining knowledge from engineering, biology, pharmacology. This study presents detailed bibliometric analysis, exploring the keywords "manufacturing," "bioactive materials," "drug delivery" identify highlight significant advancements field. From Web of Science, 36,504 articles were analyzed, 171 selected deeper identifying key journals, countries, institutions, authors. results field's interdisciplinary nature, grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, glass, tissue engineering. Future research this area will focus on more effective precise systems using technologies like 3D printing nanotechnology enhance customization control release, aiming efficient therapies.

Язык: Английский

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Therapeutic Potential of Microneedle Assisted Drug Delivery for Wound Healing: Current State of the Art, Challenges, and Future Perspective

AAPS PharmSciTech, Год журнала: 2025, Номер 26(1)

Опубликована: Янв. 8, 2025

Язык: Английский

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Chitosan-based hydrogels: A comprehensive review of transdermal drug delivery

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 140010 - 140010

Опубликована: Янв. 17, 2025

Язык: Английский

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Review on application of silk fibroin hydrogels in the management of wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 140082 - 140082

Опубликована: Янв. 18, 2025

Язык: Английский

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Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current Status, Challenges and Future Prospective

AAPS PharmSciTech, Год журнала: 2024, Номер 25(5)

Опубликована: Май 10, 2024

Язык: Английский

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Biopolymer-based hydrogels for biomedical applications: Bioactivity and wound healing properties

Coordination Chemistry Reviews, Год журнала: 2024, Номер 518, С. 216093 - 216093

Опубликована: Июль 25, 2024

Язык: Английский

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Revolutionizing the biomedical and environmental clean-up through polymeric nano-sponges: A review

Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 39, С. 101193 - 101193

Опубликована: Июнь 10, 2024

Язык: Английский

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