The Journal of Cardiovascular Aging,
Год журнала:
2023,
Номер
4(1)
Опубликована: Дек. 27, 2023
The
loss
of
skeletal
muscle,
also
known
as
sarcopenia,
is
an
aging-associated
muscle
disorder
that
disproportionately
present
in
heart
failure
(HF)
patients.
HF
patients
with
sarcopenia
have
poor
outcomes
compared
to
the
overall
patient
population.
prevalence
only
expected
grow
global
population
ages,
and
novel
treatment
strategies
are
needed
improve
this
cohort.
Multiple
mechanistic
pathways
emerged
may
explain
increased
population,
a
better
understanding
these
lead
development
therapies
prevent
loss.
This
review
article
aims
explore
molecular
mechanisms
linking
HF,
discuss
aimed
at
addressing
such
signals.
Journal of Personalized Medicine,
Год журнала:
2024,
Номер
14(6), С. 578 - 578
Опубликована: Май 28, 2024
Age-related
sleep
disorders
share
common
pathways
with
sarcopenia.
Prospective
data
from
Latin
American
populations
are
scarce,
and
the
association
between
sarcopenia
in
Chileans
remains
unknown.
Thus,
we
aimed
to
study
longitudinal
a
cohort
of
1116
community-dwelling
Chilean
older
people
≥60
years
old
ALEXANDROS
cohorts.
After
exclusion
criteria,
318
subjects
were
followed.
Sociodemographic
data,
self-reported
chronic
diseases,
sedentarism,
characteristics,
anthropometric
measurements,
handgrip
strength,
muscle
performance
assessed.
Results
indicated
that
at
baseline,
prevalence
was
24.10%
without
gender
differences,
problems
23.3%,
higher
women
(26.46%
versus
17.15%
men).
The
adjusted
Cox
regression
models
for
showed
an
sarcopenia,
(HR
=
2.08,
95%
IC
1.14–3.80),
long
duration
2.42,
1.20–4.91).
8.24
follow-up,
there
2.2
cases
per
100
person-years.
This
demonstrates
independent
risk
factor
people.
identification
through
provides
opportunity
early
cost-effective
prevention.
Food Reviews International,
Год журнала:
2023,
Номер
40(9), С. 2539 - 2579
Опубликована: Ноя. 12, 2023
Although
sarcopenia
has
been
a
serious
public
health
concern
worldwide
in
recent
years,
its
effective
prevention
and
intervention
measures
are
still
lacking.
The
latest
research
found
that
autophagy
dysfunction
is
an
essential
mechanism
the
pathogenesis
of
sarcopenia.
And
meanwhile,
increasing
studies
have
shown
phytonutrients
consumption
positively
correlated
with
maintenance
skeletal
muscle
mass
strength,
which
involves
regulation
pathway.
However,
due
to
opposite
environmental-dependent
effect
sarcopenia,
targeting
by
as
treatment
sometimes
considered
controversial.
Thus,
this
review,
based
on
illustration
relationship
between
complex
changes
ameliorating
regulating
reviewed
emphasis,
possible
underlying
mechanisms
systematically
summarized.
Despite
some
controversies,
most
current
support
idea
maintaining
basal
functional
contributes
Several
exhibit
substantial
beneficial
effects
autophagy,
polyphenols
(especially
catechins
urolithin
A)
be
potentially
clinical
relevance.
Hence,
development
promising
approach
complications.
The Journal of Cardiovascular Aging,
Год журнала:
2023,
Номер
4(1)
Опубликована: Дек. 27, 2023
The
loss
of
skeletal
muscle,
also
known
as
sarcopenia,
is
an
aging-associated
muscle
disorder
that
disproportionately
present
in
heart
failure
(HF)
patients.
HF
patients
with
sarcopenia
have
poor
outcomes
compared
to
the
overall
patient
population.
prevalence
only
expected
grow
global
population
ages,
and
novel
treatment
strategies
are
needed
improve
this
cohort.
Multiple
mechanistic
pathways
emerged
may
explain
increased
population,
a
better
understanding
these
lead
development
therapies
prevent
loss.
This
review
article
aims
explore
molecular
mechanisms
linking
HF,
discuss
aimed
at
addressing
such
signals.
