Critical Reviews in Environmental Science and Technology,
Год журнала:
2019,
Номер
50(8), С. 816 - 867
Опубликована: Июль 3, 2019
Nucleic
acids
in
the
form
of
aptamers
play
a
growing
and
significant
role
targeted
rapid
analysis
environmental
sample
composition
medical
analyses.
In
this
paper,
review
both
synthesis
methods
as
well
application
these
short
chain
oligonucleotides
(with
critical
comments
on
their
strong
weak
features)
are
given.
The
first
ones
include:
systematic
evolution
ligands
by
exponential
enrichment
(SELEX),
high
throughput
aptamer
identification
screen
(HAPIscreen),
non-equilibrium
capillary
electrophoresis
equilibrium
mixture
(NECEEM).
Afterwards,
manuscript
describes
variety
sensors
biotests
utilizing
active
part
its
action
starting
from
electrochemical
aptasensors,
through
optical
to
piezo-electric
ones.
Described
present
basic
developments
enzyme-linked
apta-sorbent
assays
(ELASA)
that
can
be
performed
with
different
variations
(enzyme-linked
assay
(ELAA),
oligonucleotide
(ELONA)
aptamer-linked
immobilized
sorbent
(ALISA)).
Next,
presents
advantages
drawbacks
recent
aptameric
versatile
laboratory
applications,
namely
ones,
analytical
bioassays.
Utilitarian
development
aptasensors
would
strongly
benefit
an
assembly
interdisciplinary
teams
containing
chemists,
physicists,
biologists,
doctors,
material
electronic
scientists,
determine
most
effective
methodologies.
Sensors,
Год журнала:
2021,
Номер
21(19), С. 6578 - 6578
Опубликована: Окт. 1, 2021
Electrochemical
impedance
spectroscopy
(EIS)
is
a
powerful
technique
used
for
the
analysis
of
interfacial
properties
related
to
bio-recognition
events
occurring
at
electrode
surface,
such
as
antibody–antigen
recognition,
substrate–enzyme
interaction,
or
whole
cell
capturing.
Thus,
EIS
could
be
exploited
in
several
important
biomedical
diagnosis
and
environmental
applications.
However,
one
most
complex
electrochemical
methods,
therefore,
this
review
introduced
basic
concepts
theoretical
background
impedimetric
along
with
state
art
biosensors
impact
nanomaterials
on
performance.
The
use
nanoparticles,
nanotubes,
nanowires,
nanocomposites
provided
catalytic
activity,
enhanced
sensing
elements
immobilization,
promoted
faster
electron
transfer,
increased
reliability
accuracy
reported
sensors.
was
effective
quantitative
qualitative
detections
pathogens,
DNA,
cancer-associated
biomarkers,
etc.
Through
article,
intensive
literature
highlight
enhancing
analytical
features
biosensors.
Molecules,
Год журнала:
2019,
Номер
24(5), С. 941 - 941
Опубликована: Март 7, 2019
Aptamers
are
short,
single-stranded
DNA,
RNA,
or
synthetic
XNA
molecules
that
can
be
developed
with
high
affinity
and
specificity
to
interact
any
desired
targets.
They
have
been
widely
used
in
facilitating
discoveries
basic
research,
ensuring
food
safety
monitoring
the
environment.
Furthermore,
aptamers
play
promising
roles
as
clinical
diagnostics
therapeutic
agents.
This
review
provides
update
on
recent
advances
this
rapidly
progressing
field
of
research
particular
emphasis
generation
their
applications
biosensing,
biotechnology
medicine.
The
limitations
future
directions
target
specific
delivery
real-time
detection
also
discussed.
Sensors,
Год журнала:
2017,
Номер
17(12), С. 2918 - 2918
Опубликована: Дек. 15, 2017
The
environmental
monitoring
has
been
one
of
the
priorities
at
European
and
global
scale
due
to
close
relationship
between
pollution
human
health/socioeconomic
development.
In
this
field,
biosensors
have
widely
employed
as
cost-effective,
fast,
in
situ,
real-time
analytical
techniques.
need
portable,
rapid,
smart
biosensing
devices
explains
recent
development
with
new
transduction
materials,
obtained
from
nanotechnology,
for
multiplexed
pollutant
detection,
involving
multidisciplinary
experts.
This
review
article
provides
an
update
on
progress
air,
water,
soil
pollutants
real
conditions
such
pesticides,
potentially
toxic
elements,
small
organic
molecules
including
toxins
endocrine
disrupting
chemicals.
Chemical Reviews,
Год журнала:
2022,
Номер
122(12), С. 11131 - 11168
Опубликована: Июнь 10, 2022
Interpretation
of
impedance
spectroscopy
data
requires
both
a
description
the
chemistry
and
physics
that
govern
system
an
assessment
error
structure
measurement.
The
approach
presented
here
includes
use
graphical
methods
to
guide
model
development,
measurement
analysis
assess
presence
stochastic
bias
errors,
systematic
development
interpretation
models
in
terms
proposed
reaction
mechanism
physical
description.
Application
corrosion,
batteries,
biological
systems
is
discussed,
emerging
trends
implementation
are
presented.
Sensors,
Год журнала:
2022,
Номер
22(19), С. 7539 - 7539
Опубликована: Окт. 5, 2022
Modern
life
quality
is
strongly
supported
by
the
advances
made
in
biosensors,
which
has
been
attributed
to
their
crucial
and
viable
contribution
point-of-care
(POC)
technology
developments.
POC
devices
are
exploited
for
fast
tracing
of
disease
progression,
rapid
analysis
water,
food
assessment.
Blood
glucose
meters,
home
pregnancy
strips,
COVID-19
tests
all
represent
common
examples
successful
biosensors.
Biosensors
can
provide
great
specificity
due
incorporation
selective
bio-recognition
elements
portability
at
significantly
reduced
costs.
Electrochemical
biosensor
platforms
one
most
advantageous
these
because
they
offer
many
merits,
such
as
being
cheap,
selective,
specific,
rapid,
portable.
Furthermore,
be
incorporated
into
smartphones
various
analytical
approaches
order
increase
sensitivity
other
properties.
As
a
very
broad
interdisciplinary
area
research
development,
biosensors
include
disciplines
backgrounds
from
materials
science,
chemistry,
physics,
medicine,
microbiology/biology,
engineering.
Accordingly,
this
state-of-the-art
article,
historical
background
alongside
long
journey
biosensing
construction
starting
Clark
oxygen
electrode
until
reaching
highly
advanced
wearable
stretchable
devices,
discussed.
Consequently,
selected
among
miscellaneous
applications
nanobiosensors
(such
microbial
detection,
cancer
diagnosis,
toxicity
analysis,
quality-control
assurance,
point
care,
health
prognosis)
described.
Eventually,
future
perspectives
intelligent
commercialization
exploitation
real-life
that
going
machine
learning
artificial
intelligence
(AI)
stated.
Biosensors,
Год журнала:
2020,
Номер
10(4), С. 32 - 32
Опубликована: Апрель 2, 2020
Pesticides
are
among
the
most
important
contaminants
in
food,
leading
to
global
health
problems.
While
conventional
techniques
such
as
high-performance
liquid
chromatography
(HPLC)
and
mass
spectrometry
(MS)
have
traditionally
been
utilized
for
detection
of
food
contaminants,
they
relatively
expensive,
time-consuming
labor
intensive,
limiting
their
use
point-of-care
(POC)
applications.
Electrochemical
(bio)sensors
emerging
devices
meeting
expectations,
since
represent
reliable,
simple,
cheap,
portable,
selective
easy
analytical
tools
that
can
be
used
outside
laboratories
by
non-specialized
personnel.
Screen-printed
electrodes
(SPEs)
stand
out
from
variety
transducers
electrochemical
(bio)sensing
because
small
size,
high
integration,
low
cost
ability
measure
few
microliters
sample.
In
this
context,
review
article,
we
summarize
discuss
about
SPEs
development
pesticides
interest
control.
Finally,
aspects
related
performance
developed
together
with
prospects
future
improvements
discussed.
Biosensors,
Год журнала:
2018,
Номер
8(2), С. 28 - 28
Опубликована: Март 23, 2018
Food
and
environmental
monitoring
is
one
of
the
most
important
aspects
dealing
with
recent
threats
to
human
well-being
ecosystems.
In
this
framework,
electrochemical
aptamer-based
sensors
are
resilient
due
their
ability
resolve
food
contamination.
An
sensor
a
compact
analytical
device
combining
an
aptamer
as
bio-sensing
element
integrated
on
transducer
surface.
Aptamers
display
many
advantages
biorecognition
elements
in
development
when
compared
affinity-based
(antibodies)
sensors.
Aptasensors
small,
chemically
unchanging,
inexpensive.
Moreover,
they
offer
extraordinary
elasticity
expediency
design
assemblies,
which
has
led
innovative
that
show
tremendous
sensitivity
selectivity.
This
review
will
emphasize
safeguarding
using
aptasensors;
there
good
prospects
for
performance
supplement
classical
techniques.
