Aptamer based tools for environmental and therapeutic monitoring: A review of developments, applications, future perspectives DOI
Błażej Kudłak, Monika Wieczerzak

Critical Reviews in Environmental Science and Technology, Journal Year: 2019, Volume and Issue: 50(8), P. 816 - 867

Published: July 3, 2019

Nucleic acids in the form of aptamers play a growing and significant role targeted rapid analysis environmental sample composition medical analyses. In this paper, review both synthesis methods as well application these short chain oligonucleotides (with critical comments on their strong weak features) are given. The first ones include: systematic evolution ligands by exponential enrichment (SELEX), high throughput aptamer identification screen (HAPIscreen), non-equilibrium capillary electrophoresis equilibrium mixture (NECEEM). Afterwards, manuscript describes variety sensors biotests utilizing active part its action starting from electrochemical aptasensors, through optical to piezo-electric ones. Described present basic developments enzyme-linked apta-sorbent assays (ELASA) that can be performed with different variations (enzyme-linked assay (ELAA), oligonucleotide (ELONA) aptamer-linked immobilized sorbent (ALISA)). Next, presents advantages drawbacks recent aptameric versatile laboratory applications, namely ones, analytical bioassays. Utilitarian development aptasensors would strongly benefit an assembly interdisciplinary teams containing chemists, physicists, biologists, doctors, material electronic scientists, determine most effective methodologies.

Language: Английский

Electrochemical Impedance Spectroscopy (EIS): Principles, Construction, and Biosensing Applications DOI Creative Commons
Hend S. Magar, Rabeay Y. A. Hassan, Ashok Mulchandani

et al.

Sensors, Journal Year: 2021, Volume and Issue: 21(19), P. 6578 - 6578

Published: Oct. 1, 2021

Electrochemical impedance spectroscopy (EIS) is a powerful technique used for the analysis of interfacial properties related to bio-recognition events occurring at electrode surface, such as antibody–antigen recognition, substrate–enzyme interaction, or whole cell capturing. Thus, EIS could be exploited in several important biomedical diagnosis and environmental applications. However, one most complex electrochemical methods, therefore, this review introduced basic concepts theoretical background impedimetric along with state art biosensors impact nanomaterials on performance. The use nanoparticles, nanotubes, nanowires, nanocomposites provided catalytic activity, enhanced sensing elements immobilization, promoted faster electron transfer, increased reliability accuracy reported sensors. was effective quantitative qualitative detections pathogens, DNA, cancer-associated biomarkers, etc. Through article, intensive literature highlight enhancing analytical features biosensors.

Language: Английский

Citations

723

Recent Advances in Aptamer Discovery and Applications DOI Creative Commons
Yang Zhang,

Bo Shiun Lai,

Mario Juhas

et al.

Molecules, Journal Year: 2019, Volume and Issue: 24(5), P. 941 - 941

Published: March 7, 2019

Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be developed with high affinity and specificity to interact any desired targets. They have been widely used in facilitating discoveries basic research, ensuring food safety monitoring the environment. Furthermore, aptamers play promising roles as clinical diagnostics therapeutic agents. This review provides update on recent advances this rapidly progressing field of research particular emphasis generation their applications biosensing, biotechnology medicine. The limitations future directions target specific delivery real-time detection also discussed.

Language: Английский

Citations

567

Recent Progress in Biosensors for Environmental Monitoring: A Review DOI Creative Commons
Celine I.L. Justino, Armando C. Duarte, Teresa Rocha‐Santos

et al.

Sensors, Journal Year: 2017, Volume and Issue: 17(12), P. 2918 - 2918

Published: Dec. 15, 2017

The environmental monitoring has been one of the priorities at European and global scale due to close relationship between pollution human health/socioeconomic development. In this field, biosensors have widely employed as cost-effective, fast, in situ, real-time analytical techniques. need portable, rapid, smart biosensing devices explains recent development with new transduction materials, obtained from nanotechnology, for multiplexed pollutant detection, involving multidisciplinary experts. This review article provides an update on progress air, water, soil pollutants real conditions such pesticides, potentially toxic elements, small organic molecules including toxins endocrine disrupting chemicals.

Language: Английский

Citations

369

Impedance Analysis of Electrochemical Systems DOI
Vincent Vivier, Mark E. Orazem

Chemical Reviews, Journal Year: 2022, Volume and Issue: 122(12), P. 11131 - 11168

Published: June 10, 2022

Interpretation of impedance spectroscopy data requires both a description the chemistry and physics that govern system an assessment error structure measurement. The approach presented here includes use graphical methods to guide model development, measurement analysis assess presence stochastic bias errors, systematic development interpretation models in terms proposed reaction mechanism physical description. Application corrosion, batteries, biological systems is discussed, emerging trends implementation are presented.

Language: Английский

Citations

318

Aptasensors for pesticide detection DOI Creative Commons
Mei Liu, Arshad Khan, Zhifei Wang

et al.

Biosensors and Bioelectronics, Journal Year: 2019, Volume and Issue: 130, P. 174 - 184

Published: Jan. 15, 2019

Language: Английский

Citations

251

Recent advances in nanomaterials-based electrochemical (bio)sensors for pesticides detection DOI
Weiran Wang,

Xinxian Wang,

Nan Cheng

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2020, Volume and Issue: 132, P. 116041 - 116041

Published: Sept. 18, 2020

Language: Английский

Citations

156

Recent advances in aptamer-based optical and electrochemical biosensors for detection of pesticides and veterinary drugs DOI

Miaojia Xie,

Fengguang Zhao,

Yaping Zhang

et al.

Food Control, Journal Year: 2021, Volume and Issue: 131, P. 108399 - 108399

Published: July 4, 2021

Language: Английский

Citations

110

Advances in Electrochemical Nano-Biosensors for Biomedical and Environmental Applications: From Current Work to Future Perspectives DOI Creative Commons
Rabeay Y. A. Hassan

Sensors, Journal Year: 2022, Volume and Issue: 22(19), P. 7539 - 7539

Published: Oct. 5, 2022

Modern life quality is strongly supported by the advances made in biosensors, which has been attributed to their crucial and viable contribution point-of-care (POC) technology developments. POC devices are exploited for fast tracing of disease progression, rapid analysis water, food assessment. Blood glucose meters, home pregnancy strips, COVID-19 tests all represent common examples successful biosensors. Biosensors can provide great specificity due incorporation selective bio-recognition elements portability at significantly reduced costs. Electrochemical biosensor platforms one most advantageous these because they offer many merits, such as being cheap, selective, specific, rapid, portable. Furthermore, be incorporated into smartphones various analytical approaches order increase sensitivity other properties. As a very broad interdisciplinary area research development, biosensors include disciplines backgrounds from materials science, chemistry, physics, medicine, microbiology/biology, engineering. Accordingly, this state-of-the-art article, historical background alongside long journey biosensing construction starting Clark oxygen electrode until reaching highly advanced wearable stretchable devices, discussed. Consequently, selected among miscellaneous applications nanobiosensors (such microbial detection, cancer diagnosis, toxicity analysis, quality-control assurance, point care, health prognosis) described. Eventually, future perspectives intelligent commercialization exploitation real-life that going machine learning artificial intelligence (AI) stated.

Language: Английский

Citations

78

Electrochemical (Bio)Sensors for Pesticides Detection Using Screen-Printed Electrodes DOI Creative Commons
Beatriz Pérez-Fernández, Agustín Costa‐García, Alfredo de la Escosura‐Muñiz

et al.

Biosensors, Journal Year: 2020, Volume and Issue: 10(4), P. 32 - 32

Published: April 2, 2020

Pesticides are among the most important contaminants in food, leading to global health problems. While conventional techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) have traditionally been utilized for detection of food contaminants, they relatively expensive, time-consuming labor intensive, limiting their use point-of-care (POC) applications. Electrochemical (bio)sensors emerging devices meeting expectations, since represent reliable, simple, cheap, portable, selective easy analytical tools that can be used outside laboratories by non-specialized personnel. Screen-printed electrodes (SPEs) stand out from variety transducers electrochemical (bio)sensing because small size, high integration, low cost ability measure few microliters sample. In this context, review article, we summarize discuss about SPEs development pesticides interest control. Finally, aspects related performance developed together with prospects future improvements discussed.

Language: Английский

Citations

134

Electrochemical Aptasensors for Food and Environmental Safeguarding: A Review DOI Creative Commons
Geetesh K. Mishra, Vinay S. Sharma, Rupesh K. Mishra

et al.

Biosensors, Journal Year: 2018, Volume and Issue: 8(2), P. 28 - 28

Published: March 23, 2018

Food and environmental monitoring is one of the most important aspects dealing with recent threats to human well-being ecosystems. In this framework, electrochemical aptamer-based sensors are resilient due their ability resolve food contamination. An sensor a compact analytical device combining an aptamer as bio-sensing element integrated on transducer surface. Aptamers display many advantages biorecognition elements in development when compared affinity-based (antibodies) sensors. Aptasensors small, chemically unchanging, inexpensive. Moreover, they offer extraordinary elasticity expediency design assemblies, which has led innovative that show tremendous sensitivity selectivity. This review will emphasize safeguarding using aptasensors; there good prospects for performance supplement classical techniques.

Language: Английский

Citations

115