Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 605 - 628
Опубликована: Янв. 1, 2025
Biosensors, Год журнала: 2023, Номер 13(1), С. 125 - 125
Опубликована: Янв. 11, 2023
Electrochemical immunosensors have attracted immense attention due to the ease of mass electrode production and high compatibility miniature electric reader, which is beneficial for developing point-of-care diagnostic devices. can be divided into label-free label-based sensing strategies equipped with potentiometric, amperometric, voltammetric, or impedimetric detectors. Emerging nanomaterials are frequently used on electrochemical as a highly rough conductive interface electrodes nanocarriers immobilizing capture antibodies, electroactive mediators, catalyzers. Adopting increase immunosensor characteristics lower detection limits better sensitivity. Recent research has shown innovative immobilization procedures meet requirements different immunosensors. This review discusses past five years advances in (metal nanoparticles, metal nanostructures, carbon nanotubes, graphene) integrated immunosensor. Furthermore, new tendency endeavors nanomaterial-based discussed.
Язык: Английский
Процитировано
58
Advanced Science, Год журнала: 2024, Номер 11(31)
Опубликована: Июнь 18, 2024
Since two-dimensionalal (2D) materials have distinct chemical and physical properties, they are widely used in various sectors of modern technologies. In the domain diagnostic biodevices, particularly for point-of-care (PoC) biomedical diagnostics, 2D-based field-effect transistor biosensors (bio-FETs) demonstrate substantial potential. Here, this review article, operational mechanisms detection capabilities biosensing devices utilizing graphene, transition metal dichalcogenides (TMDCs), black phosphorus, other 2D addressed detail. The incorporation these into FET-based offers significant advantages, including low limits (LOD), real-time monitoring, label-free diagnosis, exceptional selectivity. also highlights diverse applications biosensors, ranging from conventional to wearable devices, underscoring versatility material-based FET devices. Additionally, provides a comprehensive assessment limitations challenges faced by along with insights future prospects advancements. Notably, detailed comparison is tabulated platforms their working mechanisms. Ultimately, aims stimulate further research innovation field while educating scientific community about latest advancements materials-based biosensors.
Язык: Английский
Процитировано
19
Analytical Chemistry, Год журнала: 2021, Номер 93(46), С. 15501 - 15507
Опубликована: Ноя. 8, 2021
Tumor-derived exosomal miRNAs may have important functions in the onset and progression of cancers are potential biomarkers for early diagnosis prognosis monitoring. Yet, simple, sensitive, label-free detection remains challenging. Herein, an ultrasensitive, label-free, stable field-effect transistor (FET) biosensor based on a polymer-sorted high-purity semiconducting carbon nanotube (CNT) film is reported to detect miRNA. Different from conventional CNT FETs, FET biosensors employed floating gate structure using ultrathin Y2O3 as insulating layer, assembled Au nanoparticles (AuNPs) linkers anchor probe molecules. A thiolated oligonucleotide was immobilized AuNP surface sensing area, after which miRNA21 detectable by monitoring current change before hybridization between DNA target This method achieved both high sensitivity (LOD: 0.87 aM) specificity. Furthermore, test clinical plasma samples, showing significant differences healthy people breast cancer patients. The shows applications cancer.
Язык: Английский
Процитировано
105
Exploration, Год журнала: 2023, Номер 3(3)
Опубликована: Май 11, 2023
Nano-biosensors that are composed of recognition molecules and nanomaterials have been extensively utilized in disease diagnosis, health management, environmental monitoring. As a type nano-biosensors, molecular specificity field-effect transistor (FET) biosensors with signal amplification capability exhibit prominent advantages including fast response speed, ease miniaturization, integration, promising their high sensitivity for detection identification. With intrinsic characteristics stability structural tunability, aptamer has become one the most commonly applied biological units FET sensing fields. This review summarizes recent progress based on functionalized medical diagnosis The structure, principles, preparation methods, functionalization strategies modified were comprehensively summarized. relationship between structure performance was reviewed. Furthermore, challenges future perspectives also discussed, so as to provide support development efficient healthcare management monitoring devices.
Язык: Английский
Процитировано
40
ACS Sensors, Год журнала: 2024, Номер 9(9), С. 4536 - 4554
Опубликована: Сен. 16, 2024
Laser-induced graphene (LIG) and Laser-scribed (LSG) are both advanced materials with significant potential in various applications, particularly the field of sustainable sensors. The practical uses LIG (LSG), which include gas detection, biological process monitoring, strain assessment, environmental variable tracking, thoroughly examined this review paper. Its tunable characteristics distinguish is developed from accurate laser beam modulation on polymeric substrates, they essential advancing sensing technologies many applications. recent advances applications energy storage, biosensing, electronics by steadily efficiency versatility. remarkable flexibility its transformative regard to sensor manufacturing utilization highlighted manuscript. Moreover, it examines fabrication methods used production, highlighting precision adaptability. This navigates difficulties that encountered implementing sensors looks ahead future developments will propel industry forward. paper provides a comprehensive summary latest research elucidates innovative material's elements.
Язык: Английский
Процитировано
14
Measurement, Год журнала: 2024, Номер 236, С. 115073 - 115073
Опубликована: Июнь 6, 2024
Язык: Английский
Процитировано
11
Chemical Engineering Journal, Год журнала: 2024, Номер 488, С. 150987 - 150987
Опубликована: Апрель 3, 2024
Язык: Английский
Процитировано
10
Journal of Hazardous Materials, Год журнала: 2021, Номер 418, С. 126301 - 126301
Опубликована: Июнь 2, 2021
Язык: Английский
Процитировано
45
Small Science, Год журнала: 2022, Номер 2(8)
Опубликована: Июнь 22, 2022
In recent years, 2D oxides have attracted considerable attention due to their novel physical properties and excellent stability. With the efforts of researchers, significant progress has been made in synthesis electronics optoelectronics application oxides. Herein, a systematic review focusing on preparation applications is provided. First, are summarized classified according elements. Then, common methods synthesize including exfoliation, liquid‐phase synthesis, vapor deposition, surface oxidation metal, so introduced. Further, presented. Finally, current challenges envisioned development commented prospected.
Язык: Английский
Процитировано
30
Sensors and Actuators B Chemical, Год журнала: 2023, Номер 381, С. 133417 - 133417
Опубликована: Янв. 23, 2023
Язык: Английский
Процитировано
21