Machine Learning-assisted Melamine-Cu Nanozyme and Cholinesterase Integrated Array for Multi-category Pesticide Intelligent Recognition

Biosensors and Bioelectronics, Год журнала: 2024, Номер 266, С. 116747 - 116747

Опубликована: Сен. 4, 2024

Язык: Английский

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Smartphone-integrated colorimetric sensor for rapid detection of phenolic compounds based on the peroxidase-mimicking activity of copper/cerium-aspartic acid metal–organic framework

Microchimica Acta, Год журнала: 2025, Номер 192(1)

Опубликована: Янв. 1, 2025

Язык: Английский

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An instrument-free photoluminescent sensor array based on “turn-off” bimetallic lanthanide metal–organic frameworks for antibiotic determination

Sensors and Actuators B Chemical, Год журнала: 2023, Номер 397, С. 134671 - 134671

Опубликована: Сен. 27, 2023

Язык: Английский

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Colorimetric sensors for detection of organophosphorus pesticides in food: From sensing strategies to chemometrics driven discrimination

Trends in Food Science & Technology, Год журнала: 2024, Номер 152, С. 104683 - 104683

Опубликована: Авг. 24, 2024

Язык: Английский

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Ultrasmall CuMn-His Nanozymes with Multienzyme Activity at Neutral pH: Construction of a Colorimetric Sensing Array for Biothiol Detection and Disease Identification

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(27), С. 34538 - 34548

Опубликована: Июнь 28, 2024

Biothiol assays offer vital insights into health assessment and facilitate the early detection of potential issues, thereby enabling timely effective interventions. In this study, we developed ultrasmall CuMn-Histidine (His) nanozymes with multiple enzymatic activities. CuMn-His enhanced peroxidase (POD)-like activity at neutral pH was achieved through hydrogen bonding electrostatic effects. addition, possesses laccase (LAC)-like superoxide dismutase (SOD)-like activities pH. Based on three different enzyme mimetic pH, colorimetric sensing array without changing buffer solution successfully constructed. The used for identification biothiols, glutathione (GSH), cysteine (Cys), homocysteine (Hcy). Subsequently, excellent application results were shown in complex serum cellular level analyses. This study provides an innovative strategy development bimetallic construction arrays.

Язык: Английский

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Carbon Dots Dually Doped with Fe and Co for Visual Detection of H₂O₂ and Glutathione

ACS Applied Nano Materials, Год журнала: 2024, Номер 7(15), С. 17795 - 17803

Опубликована: Июль 29, 2024

Hydrogen peroxide (H2O2) and glutathione (GSH) have been reported to be associated with a variety of diseases. Therefore, the accurate rapid determination H2O2 GSH was very important. The traditional assay colorimetric method, which suffered from bottleneck single-mode analysis. In this work, we designed dual-mode fluorescence sensor for detecting based on bifunctional Fe, Co-CDs, possessed peroxidase (POD)-mimetic activity property. Concretely, Co-CDs catalyzed oxidation 3,3′,5,5′-tetramethylbenzidine (TMB) blue product (oxTMB) help H2O2, could inhibited by GSH. Meanwhile, weakened increasing oxTMB, realizing analysis sensors, detection limit (LOD) reach as low 0.54 μM 0.81 μM, well LOD 0.39 0.61 respectively. Besides, smartphone-assisted hydrogel developed on-site via color change. This study not only dual-target but also provided insights further exploration multifunctional nanozymes.

Язык: Английский

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A colorimetric sensor array based on nanoceria crosslinked and heteroatom-doped graphene oxide nanoribbons for the detection and discrimination of multiple pesticides

Analytica Chimica Acta, Год журнала: 2023, Номер 1283, С. 341929 - 341929

Опубликована: Окт. 19, 2023

Язык: Английский

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Encapsulation of Enzymes into Hydrophilic and Biocompatible Metal Azolate Framework: Improved Functions of Biocatalyst in Cascade Reactions and its Sensing Applications

Small, Год журнала: 2024, Номер 20(31)

Опубликована: Март 22, 2024

Multiple enzyme-triggered cascade biocatalytic reactions are vital in vivo or vitro, considering the basic biofunction preservation living organisms and signals transduction for biosensing platforms. Encapsulation of such enzymes into carrier endows a sheltering effect can boost catalytic performance, although selection preparation an appropriate is still concern. Herein, focusing on MAF-7, category metal azolate framework (MAF) with superiority against topologically identical ZIF-8, this enzyme@MAF system ameliorate sustainability encapsulating natural carriers. The proposed biocatalyst composite AChE@ChOx@MAF-7/hemin constructed via one-pot situ coprecipitation method. Subsequently, MAF-7 demonstrated to exhibit excellent capacity protection external factors counterpart ZIF-8 through encapsulated free enzymes. In addition, detections specific substrates inhibitors favorable sensitivity accomplished, indicating that properties above expectation different aspects established platform successfully realized. This biofunctional based definitely provide potential approach optimization reaction enzyme encapsulation.

Язык: Английский

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Optimization of metal–organic framework nanozyme activity via histidine modification for simultaneous pesticide detection

Chemical Engineering Journal, Год журнала: 2024, Номер 493, С. 152630 - 152630

Опубликована: Май 28, 2024

Язык: Английский

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Kinetics Difference-driven Organophosphorus Hydrolase-like Nanozyme-Coded Pattern for Identifying p-Nitrophenyl Pesticides

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

Organophosphorus pesticides (OPs) are widely used in agricultural production, posing a great threat to human health and the environment. Given that different OPs present toxicology toxicities, identifying individual pesticide residues becomes important for assessing food safety environmental implications. In this work, kinetics difference-driven analyte hydrolysis strategy is proposed first time validated identify p-nitrophenyl by developing an organophosphorus hydrolase-like nanozyme-coded sensor array. Ultrasmall bare CeO2 nanoparticles were synthesized employed as only sensing unit catalyze of multiple analytes. With catalytic preferences differences under identical reaction conditions, five common analogues (methyl-paraoxon, paraoxon, methyl-parathion, parathion, fenitrothion) offered discriminable colors. By coupling color fingerprints with pattern recognition, accurate identification their mixtures at variety concentrations ratios was verified laboratory practical scenarios. Attractively, apart from excellent performance convenient operation, hydrolytic presents strong resistance against redox substances often cause interference previous oxidoreductase-based arrays. Our study provides new paradigm discriminating specific precisely, showing promising applications multitarget analysis complex matrices.

Язык: Английский

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