Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Год журнала: 2025, Номер unknown

Опубликована: Фев. 19, 2025

To effectively address crisis emergence of new virus such as monkeypox, a collective and collaborative effort between scientists, engineers, innovators, artists from all ages, regions, diverse fields is required. This review explores holistic approach to addressing the monkeypox by integrating nanobiosensors, artificial intelligence, visual arts, humanities, social sciences. Traditional diagnostic methods are often limited time, accessibility, accuracy, but advancement point‐of‐care smart nanobiosensors offers promising shift toward rapid, precise, accessible diagnostics. They enhance ability screen, diagnose, monitor infections efficiently, contributing better disease management. Beyond technological innovation, essential role sciences in fostering public engagement, understanding, acceptance tools emphasized. Visual arts can illustrate scientific concepts, making them more relatable, while storytelling through various media reduce stigma promote preventive measures. Social provide insights into cultural attitudes, behaviors, health challenges, ensuring that solutions integrated communities. By combining these disciplines, this presents comprehensive framework for resilient global system aligns with One Health principles, emphasizing interconnectedness human, animal, environmental health.

Язык: Английский

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Advances and challenges of monkeypox detection technology

Biosafety and Health, Год журнала: 2024, Номер 6(5), С. 260 - 269

Опубликована: Сен. 11, 2024

Язык: Английский

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Graphene oxide-based fluorescent biosensors for pathogenic bacteria detection: a review

Analytica Chimica Acta, Год журнала: 2024, Номер 1337, С. 343428 - 343428

Опубликована: Ноя. 17, 2024

Язык: Английский

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Platinum-based fluorescent nanozyme-driven “loong frolic pearls” multifunctional nanoplatform for tri-mode ultrasensitive detection and synergistic sterilization of Burkholderia gladioli

Food Chemistry, Год журнала: 2024, Номер 463, С. 141107 - 141107

Опубликована: Сен. 3, 2024

Язык: Английский

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The current status and future prospects of CRISPR-based detection of monkeypox virus: A review

Analytica Chimica Acta, Год журнала: 2024, Номер 1336, С. 343295 - 343295

Опубликована: Окт. 1, 2024

Язык: Английский

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Two-Dimensional Nanozyme-Catalyzed Colorimetric CRISPR Assay for the Microfluidic Detection of Monkeypox Virus

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 18, 2025

The recent monkeypox epidemic outbreaks worldwide highlight the urgent need for fast and precise diagnostic solutions, especially in resource-limited settings. Here, a two-dimensional nanozyme-catalyzed colorimetric CRISPR assay microfluidic detection of virus (MPXV) was established. We utilized graphene oxide as substrate adsorption gold seeds deposition porous Pt shell to prepare high-performance GO@Pt nanomaterials. viral nucleic acids released from clinical samples initiated single-step recombinase polymerase amplification-CRISPR/Cas13a trans-cleavage ssRNA reporters labeled with FAM biotin. These can be recognized by antibody-conjugated nanozymes streptavidin-coated magnetic beads. formed sandwich immunocomplexes catalyze oxidation colorless 3,3′,5,5′-tetramethylbenzidine distinct color change. proposed GO@Pt-catalyzed exhibited limit 1 copy/μL MPXV 60 min. Forty samples, including rash fluid swabs oral swabs, were tested 100% agreement real-time PCR. results indicate excellent potential sensitive accurate testing under resource-constrained conditions.

Язык: Английский

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A one-pot synthesized dual-emission MOFs-based ratiometric fluorescent sensor for hypersensitive and portable detection of griseofulvin

Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137613 - 137613

Опубликована: Март 1, 2025

Язык: Английский

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A Hybrid Plasmonic Nanoplatform for One-Pot DNA and Antibody Detection of Hepatitis B, Monkeypox, and Associated Infections

Nano Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

Currently, nucleic acid and antibody tests for infectious diseases are conducted independently, often resulting in fragmented diagnostics delayed clinical decision-making. Given the diversity of analytes involved diseases, comprehensive detection is essential practice. Here, we introduce One-potNASH, a novel DNA hybrid plasmonic nanoplatform that unifies within single assay. By integrating extraction-free thermal lysis 1 μL serum, One-potNASH achieves single-DNA copy sensitivity while enhancing by more than 2 orders magnitude compared to an enzyme-linked immunosorbent Clinically, hepatitis B, monkeypox (MPX), associated infections can detect multiplexed antibodies (anti-HBc, anti-HCV, anti-HIV B anti-A29L, anti-H3L, MPX) with 100% specificity. This integrated approach addresses critical needs streamlining workflows, reducing diagnosis time, enabling evaluation thereby facilitating rapid therapeutic interventions improved patient outcomes.

Язык: Английский

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CRISPR/Cas13a-triggered exonuclease III-propelled DNA amplifier for one-pot detection of microRNAs

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 114152 - 114152

Опубликована: Май 1, 2025

Язык: Английский

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Evolving CRISPR/Cas system for food safety monitoring across the food supply chain

TrAC Trends in Analytical Chemistry, Год журнала: 2024, Номер 181, С. 118050 - 118050

Опубликована: Ноя. 14, 2024

Язык: Английский

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