Microchemical Journal, Год журнала: 2024, Номер unknown, С. 112261 - 112261
Опубликована: Ноя. 1, 2024
Язык: Английский
Analytical Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 27, 2025
Microelectrodes offer exceptional sensitivity, rapid response, and versatility, making them ideal for real-time detection monitoring applications. Photoelectrochemical (PEC) sensors have shown great value in many fields due to their high fast ease of operation. Nevertheless, conventional PEC sensing relies on cumbersome external light sources bulky electrodes, hindering its miniaturization implantation, thereby limiting application disease monitoring. To overcome these limitations, we developed a nanoencapsulated optical fiber (OF)-based microelectrode. The microelectrode features TiO2/CdS nanocrystals bis (2,2′-bipyridine) (10-methylphenanthroline [3,2-a:2′3′-c] pyridine ruthenium(II) dichloride ([Ru(bpy)2dppz]2+) @dsDNA/Au@epigallocatechin gallate nanoparticle (EGCG NP) layers. And the N-terminal pro-brain natriuretic peptide (NT-proBNP) as biomarker cardiovascular diseases was explored. An extensive linear range 1–5000 pg mL–1 combined with low limit 0.36 achieved. This covers not only recommended threshold excluding clinical diagnosis individuals across all age groups but also prognostic target value. sensor exhibited excellent selectivity stability notable labeling recovery capability serum tests. Critically, successfully discriminated alterations NT-proBNP secretion levels within human smooth muscle cells, comparing pre- poststimulation by platelet-derived growth factor-BB. Even more significantly, skin puncture experiment conducted mice demonstrated remarkable implantability biological compatibility OF-PEC addresses critical challenges commonly faced microelectrodes when used implanted devices, such minimizing invasive trauma, mitigating inflammation, preventing biofouling, firmly establishing suitability development advanced implantable devices. Therefore, present OF biosensor is cost-effective, easy operate, miniaturized holds significant potential enabling precise, minimally invasive, continuous markers without causing inflammation. crucial early detection, tracking progression, facilitating personalized treatment strategies, which expands practical sensors.
Язык: Английский
Процитировано
1
ACS Sensors, Год журнала: 2024, Номер 9(11), С. 5708 - 5727
Опубликована: Ноя. 13, 2024
Sulfur-containing gases, such as H
Язык: Английский
Процитировано
3
Chemical Engineering Journal, Год журнала: 2024, Номер unknown, С. 157904 - 157904
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
3
Опубликована: Янв. 1, 2025
Endogenous hydrogen sulfide (H2S) is a crucial biological signaling molecule in the mammals. Numerous H2S sensing methods have been developed, yet there remains an urgent need for portable, online and sensitive detection of complex samples. Herein, ratiometric fluorescent optical fiber sensor was designed ultrasensitive, H2S, using nanohybrids electrostatically self-assembled from silicon quantum dots gold nanoclusters (AuNCs@SiQDs nanohybrids). The nanohybrids, acting as probe, exhibited specific response to H2S. mechanism involved static quenching effect on AuNCs fluorescence resonance energy transfer between SiQDs AuNCs. showed good linear concentration 0.01 ~ 100 μM, with ultralow limit 4.33 nM. also successfully employed rapid real serum samples, without tedious preprocessing. This approach offers portable efficient technique on-line ultrasensitive measurement well determination H2S-mediated biomolecules. method boasts high sensitivity selectivity, strong anti-interference capability, portability, practicality, ease production, making it significant disease research emergency analysis.
Язык: Английский
Процитировано
0
Nanomaterials, Год журнала: 2025, Номер 15(6), С. 417 - 417
Опубликована: Март 8, 2025
In this work, we developed 3D ionic liquid (IL) functionalized graphene assemblies (GAs) decorated by ultrafine RuCu alloy nanoparticles (RuCu-ANPs) via a one-step synthesis process, and integrated it into microfluidic sensor chip for in situ electrochemical detection of NO released from living cells. Our findings have demonstrated that RuCu-ANPs on IL-GA exhibit high density, uniform distribution, lattice-shaped arrangement atoms, extremely size, possess electrocatalytic activity to oxidation the electrode. Meanwhile, with hierarchical porous structures can facilitate efficient electron/mass transfer at electrode/electrolyte interface cell culture. Moreover, graft IL molecules GA endows hydrophilicity facile well-controllable printing Consequently, resultant excellent sensing performances including fast response time, sensitivity, good anti-interference ability, reproducibility, long-term stability, as well biocompatibility, which be used an on-chip system culture real-time cells accurate stable characteristics physiological conditions.
Язык: Английский
Процитировано
0
Sensors and Actuators B Chemical, Год журнала: 2025, Номер unknown, С. 137874 - 137874
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Food Hydrocolloids, Год журнала: 2025, Номер unknown, С. 111505 - 111505
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
Ceramics International, Год журнала: 2025, Номер unknown
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
Talanta, Год журнала: 2025, Номер 294, С. 128277 - 128277
Опубликована: Май 5, 2025
Язык: Английский
Процитировано
0
Analytica Chimica Acta, Год журнала: 2024, Номер 1324, С. 343096 - 343096
Опубликована: Авг. 12, 2024
Язык: Английский
Процитировано
2