New advances in the diagnosis and treatment of autism spectrum disorders

European journal of medical research, Год журнала: 2024, Номер 29(1)

Опубликована: Июнь 10, 2024

Язык: Английский

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Cortisol: Biosensing and detection strategies

Clinica Chimica Acta, Год журнала: 2024, Номер 562, С. 119888 - 119888

Опубликована: Июль 24, 2024

Язык: Английский

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Emerging strategies in fluorescent aptasensor toward food hazard aflatoxins detection

Trends in Food Science & Technology, Год журнала: 2022, Номер 129, С. 621 - 633

Опубликована: Ноя. 1, 2022

Язык: Английский

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Controllable‐Swelling Microneedle–Assisted Ultrasensitive Paper Sensing Platforms for Personal Health Monitoring

Advanced Healthcare Materials, Год журнала: 2023, Номер 12(24)

Опубликована: Апрель 11, 2023

Microneedle (MN) patches, which allow the extraction of skin interstitial fluid (ISF) without a pain sensation, are powerful tools for minimally invasive biofluid sampling. Herein, an MN-assisted paper-based sensing platform that enables rapid and painless analysis with ultrasensitive molecular recognition capacity is developed. First, controllable-swelling MN patch constructed through engineering poly(ethylene glycol) diacrylate/methacrylated hyaluronic acid hydrogel; it combines rapid, sufficient ISF excellent structural integrity. Notably, analyte molecules in needles can be recovered into moist cellulose paper spontaneous diffusion. More importantly, functionalized enzymatic colorimetric reagents or plasmonic array, enabling desired detection capacity-for example, use surface-enhanced Raman spectroscopy sensors leads to label-free, trace (sub-ppb level) diverse set (cefazolin, nicotine, paraquat, methylene blue). Finally, nicotine selected as model drug evaluate monitoring three human volunteers. The changes levels tracked, varying significantly response metabolism different This as-designed system should open up new opportunities precision medicine, especially personal healthcare monitoring.

Язык: Английский

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Integrated lighting ergonomics: A review on the association between non-visual effects of light and ergonomics in the enclosed cabins

Building and Environment, Год журнала: 2023, Номер 243, С. 110616 - 110616

Опубликована: Июль 13, 2023

Язык: Английский

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Advanced biosensors for mycotoxin detection incorporating miniaturized meters

Biosensors and Bioelectronics, Год журнала: 2023, Номер 224, С. 115077 - 115077

Опубликована: Янв. 11, 2023

Язык: Английский

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Progress in salivary glands: Endocrine glands with immune functions

Frontiers in Endocrinology, Год журнала: 2023, Номер 14

Опубликована: Фев. 3, 2023

The production and secretion of saliva is an essential function the salivary glands. Saliva a complicated liquid with different functions, including moistening, digestion, mineralization, lubrication, mucosal protection. This review focuses on mechanism neural regulation secretion, secreted in response to various stimuli, odor, taste, vision, mastication. chemical physical properties change dynamically during physiological pathophysiological processes. Moreover, central nervous system modulates via neurotransmitters neuroreceptors. Smell, taste have been investigated for connection between salivation brain function. immune endocrine functions glands explored recently. Salivary play role innate adaptive immunity Various cells such as B cells, T macrophages, dendritic well immunoglobins like IgA IgG found Evidence supports synthesis corticosterone, testosterone, melatonin contains many potential biomarkers derived from epithelial gingival crevicular fluid, serum. High level matrix metalloproteinases cytokines are markers oral carcinoma, infectious disease cavity, systemic disease. Further research required monitor predict health clinical practice precision medicine.

Язык: Английский

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Molecular modulation of aggregation-induced luminescence for improving response sensing of DNA hydrogels

Biosensors and Bioelectronics, Год журнала: 2025, Номер 276, С. 117254 - 117254

Опубликована: Фев. 12, 2025

Язык: Английский

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Is burning mouth syndrome associated with stress? A meta‐analysis

Journal of Oral Rehabilitation, Год журнала: 2023, Номер 50(11), С. 1279 - 1315

Опубликована: Июнь 19, 2023

Some studies have shown burning mouth syndrome (BMS) as comorbid psychosocial and psychiatric disorders, well, pointed at stress a major risk factor.The aim of this meta-analysis was to answer the following question: 'Is there an association between BMS stress, compared healthy controls?'Two reviewers searched for effect in published on five main databases three from grey literature. Various questionnaires biomarkers were analysed. Of 2489 selected articles, 30 met inclusion criteria. Studies englobed questionnaires, such Perceived Stress Questionnaire, Lipp Symptoms Inventory, Holmes-Rahe scale, Depression, Anxiety, Scale (DASS-21), Recent Experience Test; various biomarkers, cortisol, opiorphin, IgA, α-amylase interleukins.In all with significantly increased group vs. control. Patients presented 25.73% higher cortisol levels, 28.17% IgA levels 40.62% than controls. Meta-analysis found that subjects 3.01 nmoL/L [0.53; 5.50] 84.35 kU/L [15.00; 153.71] 29.25 mg/mL [9.86; 48.64] 258.59 pg/mL [59.24; 457.94] IL-8 No differences opiorphin concentration ng/mL [-0.96; 2.53]. For interleukins, no founded IL-1 β, IL-2, IL-4, IL-6, IL-8, IL-10 TNF-α.Based available evidence, suggests more factors questionnaire-based studies, α-amylase,

Язык: Английский

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Structural properties and binding mechanism of DNA aptamers sensing saliva melatonin for diagnosis and monitoring of circadian clock and sleep disorders

Analytica Chimica Acta, Год журнала: 2023, Номер 1251, С. 340971 - 340971

Опубликована: Фев. 15, 2023

Язык: Английский

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