Recent advances in encapsulation of resveratrol for enhanced delivery

Food Chemistry, Год журнала: 2024, Номер 460, С. 140475 - 140475

Опубликована: Июль 16, 2024

Язык: Английский

New Insights into the Development of Donepezil-Based Hybrid and Natural Molecules as Multi-Target Drug Agents for Alzheimer’s Disease Treatment

Molecules, Год журнала: 2024, Номер 29(22), С. 5314 - 5314

Опубликована: Ноя. 11, 2024

Alzheimer's disease (AD) involves a complex pathophysiology with multiple interconnected subpathologies, including protein aggregation, impaired neurotransmission, oxidative stress, and microglia-mediated neuroinflammation. Current treatments, which generally target single subpathology, have failed to modify the disease's progression, providing only temporary symptom relief. Multi-target drugs (MTDs) address several aggregation of pathological proteins. In this review, we cover hybrid molecules published between 2014 2024. We offer an overview strategies employed in drug design approaches that led notable improvements reduced hepatotoxicity. Our aim is insights into potential development new drugs. This highlights multi-target featuring heterocycles

Язык: Английский

RESVERATROL SUPPLEMENTATION AS A NON-SURGICAL TREATMENT IN PERIODONTITIS AND RELATED SYSTEMIC CONDITIONS

Journal of Traditional and Complementary Medicine, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 1, 2024

Язык: Английский