Microspheres: Preparation Methods, Advances, Applications, and Challenges in Drug Delivery

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Фев. 6, 2025

Язык: Английский

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Egg white-derived peptides co-assembly-reinforced zein/chondroitin sulfate nanoparticles for orally colon-targeted co-delivery of quercetin in colitis mitigation

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106161 - 106161

Опубликована: Фев. 1, 2025

Язык: Английский

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Huang Qin decoction supplemented diet attenuates Aeromonas hydrophila-induced intestinal inflammation via the Delta/notch pathway in Eriocheir sinensis

Aquaculture, Год журнала: 2025, Номер unknown, С. 742427 - 742427

Опубликована: Март 1, 2025

Язык: Английский

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Recent Advances in the Application of Hydrogels as Drug Carriers in Inflammatory Bowel Disease: A Review

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 2894 - 2894

Опубликована: Март 22, 2025

Inflammatory bowel disease (IBD) is a chronic and refractory with increasing incidence, adversely impacting millions of patients worldwide. Current therapeutic strategies for IBD often exhibit considerable adverse effects, limited efficacy, high tendency recurrence, highlighting the urgent need novel agents. Hydrogel, three-dimensional hydrophilic network polymer material known its excellent biocompatibility responsiveness to stimuli, has been effectively utilized as drug carrier across various systems. The hydrogels' application in treatment holds significant promise enhancing outcomes. This review synthesizes recent advancements leveraging hydrogels carriers management. discussion encompasses response mechanisms hydrogels, their therapy, methods administration. As delivery matrices, potential treating IBD.

Язык: Английский

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The emerging role of honeysuckle flower in inflammatory bowel disease

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Март 28, 2025

Crohn's disease (CD) and ulcerative colitis (UC), referred to as inflammatory bowel (IBD), pose considerable challenges in treatment because they are chronic conditions that easily relapse. The occurrence of IBD continues rise developing countries. Nonetheless, the existing therapies for have limitations fail address needs patients thoroughly. There is an increasing need new, safe, highly effective alternative medications patients. Traditional Chinese Medicine (TCM) employed drug development management due its wide-range biological activities, minimal toxicity, limited side effects. Extensive research has shown certain TCM exhibits significant therapeutic benefits treatments. Honeysuckle (Lonicera japonica) was used clinical settings IBD. Bioactive metabolites L. japonica, such luteolin, quercetin, cyanidin, chlorogenic acid (CGA), caffeic (CA), saponin, exhibit managing honeysuckle flower a potential candidate anti-inflammatory, immune system-regulating, antioxidant qualities. This paper reviews It discusses fundamental mechanism japonica bioactive prevention

Язык: Английский

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Recent research advances on oral colon-specific delivery system of nature bioactive components: A review

Food Research International, Год журнала: 2023, Номер 173, С. 113403 - 113403

Опубликована: Авг. 28, 2023

Язык: Английский

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Recent advances in nanocarrier systems for ulcerative colitis: A new era of targeted therapy and biomarker integration

Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 93, С. 105466 - 105466

Опубликована: Фев. 8, 2024

Язык: Английский

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Colon-targeted oral nanoliposomes loaded with psoralen alleviate DSS-induced ulcerative colitis

Biomaterials Science, Год журнала: 2024, Номер 12(12), С. 3212 - 3228

Опубликована: Янв. 1, 2024

Psoralen-loaded nanoliposomes have pH and microbiota-sensitive characteristics, which can target the colon after oral administration to play an anti-ulcerative colitis role.

Язык: Английский

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Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids

Food Bioscience, Год журнала: 2024, Номер unknown, С. 105311 - 105311

Опубликована: Окт. 1, 2024

Язык: Английский

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Traditional herbs: mechanisms to combat cellular senescence

Aging, Год журнала: 2023, Номер 15(23), С. 14473 - 14505

Опубликована: Дек. 5, 2023

Cellular senescence plays a very important role in the ageing of organisms and age-related diseases that increase with age, process involves physiological, structural, biochemical molecular changes cells. In recent years, it has been found active ingredients herbs their natural products can prevent control cellular by affecting telomerase activity, oxidative stress response, autophagy, mitochondrial disorders, DNA damage, inflammatory metabolism, intestinal flora, other factors. this paper, we review research information on prevention Chinese herbal medicine through computer searches PubMed, Web Science, Science Direct CNKI databases.

Язык: Английский

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