Bioactive Materials,
Год журнала:
2024,
Номер
40, С. 597 - 623
Опубликована: Авг. 15, 2024
Tissue
engineering
technology
has
advanced
rapidly
in
recent
years,
offering
opportunities
to
construct
biologically
active
tissues
or
organ
substitutes
repair
even
enhance
the
functions
of
diseased
and
organs.
Tissue-engineered
scaffolds
rebuild
extracellular
microenvironment
by
mimicking
matrix.
Fibrin-based
possess
numerous
advantages,
including
hemostasis,
high
biocompatibility,
good
degradability.
Fibrin
provide
an
initial
matrix
that
facilitates
cell
migration,
differentiation,
proliferation,
adhesion,
also
play
a
critical
role
cell-matrix
interactions.
are
now
widely
recognized
as
key
component
tissue
engineering,
where
they
can
facilitate
defect
repair.
This
review
introduces
properties
fibrin,
its
composition,
structure,
biology.
In
addition,
modification
cross-linking
modes
fibrin
discussed,
along
with
various
forms
commonly
used
engineering.
We
describe
biofunctionalization
fibrin.
provides
detailed
overview
use
applications
skin,
bone,
nervous
tissues,
novel
insights
into
future
research
directions
for
clinical
treatment.
Gels,
Год журнала:
2024,
Номер
10(3), С. 183 - 183
Опубликована: Март 6, 2024
Gellan
gum
(GG)
is
a
linear,
negatively
charged
exopolysaccharide
that
biodegradable
and
non-toxic.
When
metallic
ions
are
present,
hard
transparent
gel
produced,
which
remains
stable
at
low
pH.
It
exhibits
high
water
solubility,
can
be
easily
bio-fabricated,
demonstrates
excellent
film/hydrogel
formation,
biodegradable,
shows
biocompatibility.
These
characteristics
render
GG
suitable
option
for
use
in
food,
biomedical,
cosmetic
fields.
Thus,
this
review
paper
offers
concise
summary
of
microbial
polysaccharides.
Moreover,
an
in-depth
investigation
trends
different
facets
GG,
such
as
biosynthesis,
chemical
composition,
physical
properties,
emphasized.
In
addition,
highlights
the
process
extracting
purifying
GG.
Furthermore,
discussion
advantages
disadvantages
concerning
other
polysaccharides
presented.
utilization
across
industries,
medicine,
pharmaceuticals,
cosmetics,
etc.,
thoroughly
examined
will
greatly
benefit
individuals
involved
field
who
seeking
fresh
opportunities
innovative
projects
future.
Gels,
Год журнала:
2024,
Номер
10(3), С. 172 - 172
Опубликована: Фев. 28, 2024
In
recent
decades,
hydrogels
have
emerged
as
innovative
soft
materials
with
widespread
applications
in
the
medical
and
biomedical
fields,
including
drug
delivery,
tissue
engineering,
gel
dosimetry.
this
work,
a
comprehensive
study
of
macroscopic
microscopic
properties
hydrogel
matrices
based
on
Poly(vinyl-alcohol)
(PVA)
chemically
crosslinked
Glutaraldehyde
(GTA)
was
reported.
Five
different
kinds
PVAs
differing
molecular
weight
degree
hydrolysis
were
considered.
The
local
organization
studied
through
use