Marine algal polysaccharides for drug delivery applications: A review

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 295, С. 139551 - 139551

Опубликована: Янв. 7, 2025

Язык: Английский

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Loading curcumin on hyperbranched polymers functionalized Zein via the phenol-yne click reaction as pH-responsive drug delivery system for chemotherapy and photodynamic therapy

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139750 - 139750

Опубликована: Янв. 1, 2025

Язык: Английский

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Natural Regenerative Hydrogels for Wound Healing

Gels, Год журнала: 2024, Номер 10(9), С. 547 - 547

Опубликована: Авг. 23, 2024

Regenerative hydrogels from natural polymers have come forth as auspicious materials for use in regenerative medicine, with interest attributed to their intrinsic biodegradability, biocompatibility, and ability reassemble the extracellular matrix. This review covers latest advances used wound healing, focusing on chemical composition, cross-linking mechanisms, functional properties. Key carbohydrate polymers, including alginate, chitosan, hyaluronic acid, polysaccharide gums, agarose, carrageenan, xanthan gum, are discussed terms of sources, structures specific properties suitable applications. The further explores categorization based ionic charge, response physiological stimuli (i.e., pH, temperature) particularized roles tissue self-healing. Various methods enhance mechanical biological performance these also examined. By highlighting recent innovations ongoing challenges, this article intends give a detailed understanding potential revolutionize medicine improve patient healing outcomes.

Язык: Английский

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A modified hyaluronic acid hydrogel with strong bacterial capture and killing capabilities for drug-resistant bacteria-infected diabetic wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135301 - 135301

Опубликована: Сен. 3, 2024

Язык: Английский

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Exploration of Agrocybe aegerita mushroom polysaccharide-polyphenolic complex: Functional properties, binding efficiency, and biological activities

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139309 - 139309

Опубликована: Янв. 1, 2025

Язык: Английский

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Injectable and self-healing dual-network chitosan/hyaluronic acid/polypeptide (CHP) antibacterial hydrogels for wound healing

Polymer, Год журнала: 2025, Номер unknown, С. 128064 - 128064

Опубликована: Янв. 1, 2025

Язык: Английский

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Innovative Utilization of Citrus Sinensis Peel Hydrogels: Enhancing Soil Water Retention and Efficient Removal of Methylene Blue from Wastewater

Polymers, Год журнала: 2025, Номер 17(3), С. 428 - 428

Опубликована: Фев. 6, 2025

In the context of increasing water scarcity and environmental pollution, this study investigates synthesis application p(AA-Oco-AAm)-g-Citrus Sinensis Peel hydrogel (CSP hydrogel) to enhance soil retention remove organic dyes from wastewater. Hydrogels were prepared using a combination acrylamide acrylic acid, with incorporation citrus peel as natural resource. The absorption capacity hydrogels was evaluated, achieving maximum rate 477 g/g, significantly improving water-holding ability various types. Additionally, demonstrated strong affinity for methylene blue, an equilibrium adsorption reaching 2299.45 mg/g, indicating their effectiveness in wastewater treatment. Kinetic isothermal models applied analyze dynamics, revealing superior fit Langmuir model. maintained structural integrity reusability over multiple cycles, underscoring potential sustainable agricultural practices remediation. This research highlights dual benefits utilizing waste development eco-friendly materials while addressing critical challenges management pollution control.

Язык: Английский

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Mussel-inspired adhesive drug-loaded hydrogels for oral ulcers treatment

Acta Biomaterialia, Год журнала: 2024, Номер 187, С. 98 - 109

Опубликована: Авг. 28, 2024

Язык: Английский

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Feruloylation of arabinoxylan enhances the protective effects on probiotic viability and stability in tablet formulations

Carbohydrate Polymers, Год журнала: 2025, Номер 357, С. 123475 - 123475

Опубликована: Март 5, 2025

Язык: Английский

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Avaliação da toxicidade dérmica de uma formulação hidrogel de Goma Guar contendo Lactiplantibacillus plantarum M2

Caderno Pedagógico, Год журнала: 2025, Номер 22(1), С. e13127 - e13127

Опубликована: Янв. 8, 2025

Os custos elevados do tratamento de lesões epiteliais, a crescente resistência microbiana e os efeitos colaterais terapias convencionais destacam necessidade novas abordagens terapêuticas. Nesse cenário, bioprospecção compostos bioativos produtos biotecnológicos ganham relevância. Biomateriais como polissacarídeos têm apresentado excelente destaque. E formulações hidrogéis, que podem funcionar sistemas administração medicamentos curativos inteligentes respondem estímulos pH, temperatura luz, revelam ser aplicações importantes, mundialmente. Entre suas possíveis combinações promissoras estão probióticos, principalmente as bactérias ácido-láticas, apresentam potencial para estimular o sistema imunológico combater vírus, fungos. Um exemplo interessante polímero desenvolvimento probióticos tópicos é goma guar, derivada da semente leguminosa Cyamopsis tetragonolobus, se destaca por um polissacarídeo hidrofílico com propriedades gelificantes espessantes. Tais necessitam apresentar efetivo controle segurança seus usos, qualidade avaliada pela análise toxicidade dérmica, partir dos resultados testes in vivo, em camundongos, exemplo. O presente estudo buscou avaliar dérmica uma formulação desenvolvida hidrogel à base guar contendo Lactiplantibacillus plantarum M2. A metodologia empregada, envolveu avaliação formulação, dose repetida, análises parâmetros hematológicos bioquímicos ainda histopatológicas pele tratada camundongos. indicaram ausência irritação, ou alterações hematológicas histopatológicas, reforçando eficácia formulação.

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