State-of-the-art in natural hydrogel-based wound dressings: Design, functionalization, and fabrication approaches DOI Creative Commons
Hossein Baniasadi

Advances in Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 103527 - 103527

Опубликована: Апрель 1, 2025

Язык: Английский

Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin DOI Creative Commons

Monica-Cornelia Sardaru,

Irina Roșca, Simona Morariu

и другие.

Gels, Год журнала: 2025, Номер 11(1), С. 35 - 35

Опубликована: Янв. 4, 2025

In this present study, we developed and characterized a series of supramolecular G4 hydrogels by integrating β-cyclodextrin (β-CD) boronic acid linkers into matrix to enhance antibacterial activity against Staphylococcus aureus (S. aureus). We systematically investigated how varying the number free moieties (ranging from two six), along with guanosine β-CD content, influences both structural integrity antimicrobial efficacy these materials. Comprehensive characterization using FTIR, circular dichroism, X-ray diffraction, SEM, AFM, rheological measurements confirmed successful synthesis revealed that higher content correlated stronger, more organized network. The most effective hydrogel displayed an inhibition zone 25 mm in disk diffusion assays, was further explored as drug delivery platform, aim exploit capacity cavity incorporate hydrophobic drugs. Norfloxacin (Nfx), poorly water-soluble antibiotic, successfully encapsulated within through inclusion complex formation β-CD, improving its solubility enabling sustained, targeted release. Nfx-loaded expanded 49 completely eradicated S. cells 24 h, outperforming unloaded Nfx. These results highlight synergistic effect controlled release, underlining potential versatile platforms for localized therapy, such wound dressings or implant coatings. Nevertheless, vivo studies long-term stability assessments are needed fully establish clinical relevance, safety, scalability before systems can be translated routine healthcare applications.

Язык: Английский

Процитировано

0
Chitosan/alginate polyelectrolyte complex hydrogels by additive manufacturing for in vitro 3D ovarian Cancer modeling DOI
Simona Braccini, Gianni Pecorini,

Simone Biagini

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139795 - 139795

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Silk Protein-Based Triboelectric Nanogenerators for Energy Harvesting and Self-Powered Sensing DOI
Bo Shang, Chenyu Wang, Xiaoxue Wang

и другие.

Sensors and Actuators A Physical, Год журнала: 2025, Номер unknown, С. 116449 - 116449

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Surprising Multiple Enhancement Effects of Carboxymethyl Chitosan-Co in Ammonium Perchlorate-Based Propellant DOI
Haozhe Li,

Xiandie Zhang,

Heng Xu

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
State-of-the-art in natural hydrogel-based wound dressings: Design, functionalization, and fabrication approaches DOI Creative Commons
Hossein Baniasadi

Advances in Colloid and Interface Science, Год журнала: 2025, Номер unknown, С. 103527 - 103527

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0