Copper-catalyzed asymmetric [4 + 1] annulation of yne-allylic esters with pyrazolones
Chinese Chemical Letters,
Год журнала:
2024,
Номер
unknown, С. 110114 - 110114
Опубликована: Июнь 1, 2024
Язык: Английский
Construction of Amidines via palladium-catalyzed three-component reaction of Arylacetylenes, t-Butylisonitrile and O-benzoyl Hydroxylamines
Tetrahedron Letters,
Год журнала:
2025,
Номер
unknown, С. 155534 - 155534
Опубликована: Март 1, 2025
Язык: Английский
Dialkylation of 1,3-Dienes with Aldehydes and Cyclopropanols toward Homoallylic Alcohols by Dual Photoredox and Chromium Catalysis
Gaochen Xu,
Pei Guan,
Lu Deng
и другие.
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 27, 2025
A
visible-light-induced
three-component
coupling
of
aldehydes,
1,3-dienes,
and
cyclopropyl
alcohols
using
dual
photoredox
chromium
catalysis
is
herein
described.
This
efficient
protocol
achieves
the
dialkylation
1,3-dienes
toward
1,4-disubstituted
homoallylic
in
moderate
to
good
yields
with
excellent
regioselectivity,
featuring
mild
reaction
conditions,
functional
group
tolerance,
gram-scale
synthesis.
Mechanistic
study
suggests
that
photoinduced
sequential
ring
opening
alcohol
radical
nucleophilic
cascade
addition
are
involved
catalytic
cycle.
Язык: Английский
Olefin skeletal rearrangement enabling access to multiarylated N-sulfonyl amidines
Chemical Communications,
Год журнала:
2024,
Номер
60(11), С. 1492 - 1495
Опубликована: Янв. 1, 2024
A
novel
base-promoted
olefin
skeletal
rearrangement
strategy
from
para
-quinone
methides
(
p
-QMs)
and
N
-fluoroarenesulfonamides
is
reported,
enabling
direct
nitrogen
insertion
of
olefins
to
produce
multiarylated
Z
)-
-sulfonyl
amidines.
Язык: Английский
Oxidative spirolactonisation for modular access of γ-spirolactones via a radical tandem annulation pathway
Chinese Chemical Letters,
Год журнала:
2024,
Номер
35(10), С. 109565 - 109565
Опубликована: Фев. 1, 2024
Язык: Английский
Aerobic CuBr2-Catalyzed Oxidative Coupling Reaction of Amidines with Exocyclic α,β-Unsaturated Cycloketones for the Synthesis of Spiroimidazolines
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(11), С. 6729 - 6735
Опубликована: Май 8, 2023
A
CuBr2-catalyzed
cascade
reaction
of
amidines
with
exocyclic
α,β-unsaturated
cycloketones
was
developed,
affording
a
large
variety
spiroimidazolines
in
moderate
to
excellent
yields.
The
process
involved
the
Michael
addition
and
copper(II)-catalyzed
aerobic
oxidative
coupling,
which
O2
from
air
acted
as
oxidant
H2O
sole
byproduct.
Язык: Английский
Iodine promoted cyclization of N,N′-diphenylthiocarbamides with enaminones: a protocol for the synthesis of poly-substituted 2-iminothiazolines
Organic & Biomolecular Chemistry,
Год журнала:
2022,
Номер
20(43), С. 8533 - 8537
Опубликована: Янв. 1, 2022
An
iodine
promoted
cyclization
reaction
between
N
,
′-diphenylthiocarbamides
and
enaminones
was
achieved,
providing
a
series
of
poly-substituted
2-iminothiazolines.
Язык: Английский
Recent approaches for the synthesis of heterocycles from amidines via metal catalyzed C-H functionalization reaction
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(25), С. 5014 - 5031
Опубликована: Янв. 1, 2024
Transition
metal
catalyzed
C-H
bond
activation
has
become
one
of
the
most
important
tools
for
constructing
new
chemical
bonds.
Introducing
directing
groups
to
substrates
is
key
a
successful
reaction,
these
can
also
be
further
transformed
in
reaction.
Amidines
with
their
unique
structure
and
reactivity
are
ideal
transition
metal-catalyzed
transformations.
This
review
describes
major
advances
mechanistic
investigations
activation/annulation
tandem
reactions
amidines
until
early
2024,
focusing
on
unsaturated
compounds,
such
as
alkynes,
ketone,
vinylene
carbonate,
cyclopropanols
derivatives.
Meanwhile
this
manuscript
explores
reaction
different
carbene
precursors,
example
diazo
azide,
triazoles,
pyriodotriazoles,
sulfoxonium
ylides
well
own
activation/cyclization
reactions.
A
bright
outlook
provided
at
end
manuscript.
Язык: Английский
Electrochemical Reductive Bimolecular Cycloaddition of 2-Arylideneindane-1,3-diones for the Synthesis of Spirocyclopentanole Indane-1,3-diones
Luchao Li,
Binyan Xu,
Chenglong Jia
и другие.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 25, 2024
An
electrochemical
reductive
bimolecular
cycloaddition
of
2-arylideneindane-1,3-diones
has
been
reported
for
the
synthesis
spirocyclopentanole
indane-1,3-diones
bearing
five
contiguous
stereocenters
with
vicinal
tetrasubstituted
stereocenters,
especially
involving
a
quaternary
carbon
center,
in
moderate
to
good
yields
and
excellent
diastereoselectivities.
The
present
protocol
features
mild
reaction
conditions,
no
external
chemical
redox
reagents,
atom
economy,
gram-scale
synthesis.
In
addition,
mechanistic
investigation
indicates
that
reactions
proceed
through
radical
pathway.
Язык: Английский