Recent Progress in Asymmetric Michael Additions Catalyzed by Chiral Phosphoric Acids
ChemistrySelect,
Год журнала:
2025,
Номер
10(21)
Опубликована: Май 29, 2025
Abstract
Chiral
phosphoric
acids
(CPAs)
exhibit
bifunctional
catalytic
properties
due
to
their
unique
structural
features
and
chemical
characteristics,
leading
widespread
application
in
various
common
reactions.
In
addition,
the
Michael
addition
reaction
holds
significant
importance
field
of
organic
chemistry,
particularly
among
numerous
reactions
involving
carbon–carbon
carbon–heteroatom
bond
forming.
This
minireview
systematically
introduced
structure
mechanism
chiral
acid
gave
an
overview
on
development
status
catalyzed
by
acids,
including
actual
hetero‐Michael
(aza‐Michael
oxo‐Michael
phospha‐Michael
sulfa‐Michael
addition).
Язык: Английский
Molecular sieve-like wood achieves efficient chiral catalysis
Molecular Catalysis,
Год журнала:
2024,
Номер
554, С. 113834 - 113834
Опубликована: Янв. 13, 2024
Язык: Английский
Photocatalytic Carbamoyl Radical Transfer to Alkenyl Azaarenes
Synlett,
Год журнала:
2024,
Номер
35(16), С. 1883 - 1888
Опубликована: Янв. 29, 2024
Abstract
1-Phenyl-3-azaarenyl-propan-1-amine
structural
moieties
have
been
widely
incorporated
in
pharmaceuticals
and
biologically
active
compounds;
however,
current
synthetic
methods
to
access
these
compounds
need
multiple
steps
proceed
with
low
efficiency.
Herein,
we
reported
an
efficient
photocatalytic
carbamoyl
radical
transfer
approach
that
allows
the
preparation
of
high
yields
(up
88%).
The
reaction
easily
runs
on
a
gram-scale
was
applied
for
pheniramine
two
72%
total
yield.
Язык: Английский
Catalytic Asymmetric Hydrogen Atom Transfer Based on a Chiral Hydrogen Atom Donor Generated from TBADT and Chiral BINOL
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 24, 2024
Enantioselective
radical
reactions
mediated
by
TBADT
have
seldom
been
seen
due
to
the
inherent
challenges.
Herein,
we
disclose
a
new
chiral
hydrogen
atom
transfer
(HAT)
reagent
that
was
generated
easily
from
8
Язык: Английский
A central functional group-dependent stereoinduction mechanism for chiral super Brønsted C–H acid catalysis
Catalysis Science & Technology,
Год журнала:
2023,
Номер
13(24), С. 7136 - 7148
Опубликована: Янв. 1, 2023
DFT
calculations
disclosed
that
the
central
functional
group
could
induce
a
favorable
chiral
environment
and
determine
enantioselectivity
for
Brønsted
C–H
acid
catalysis.
Язык: Английский