A central functional group-dependent stereoinduction mechanism for chiral super Brønsted C–H acid catalysis DOI
Lihan Zhu, Dongqi Wang

Catalysis Science & Technology, Journal Year: 2023, Volume and Issue: 13(24), P. 7136 - 7148

Published: Jan. 1, 2023

DFT calculations disclosed that the central functional group could induce a favorable chiral environment and determine enantioselectivity for Brønsted C–H acid catalysis.

Language: Английский

Recent Progress in Asymmetric Michael Additions Catalyzed by Chiral Phosphoric Acids DOI

Zhongwen He,

Teck‐Peng Loh,

Lingzheng Bu

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(21)

Published: May 29, 2025

Abstract Chiral phosphoric acids (CPAs) exhibit bifunctional catalytic properties due to their unique structural features and chemical characteristics, leading widespread application in various common reactions. In addition, the Michael addition reaction holds significant importance field of organic chemistry, particularly among numerous reactions involving carbon–carbon carbon–heteroatom bond forming. This minireview systematically introduced structure mechanism chiral acid gave an overview on development status catalyzed by acids, including actual hetero‐Michael (aza‐Michael oxo‐Michael phospha‐Michael sulfa‐Michael addition).

Language: Английский

Citations

0
Molecular sieve-like wood achieves efficient chiral catalysis DOI
Jian Sheng, Yudong Li, Zhiyuan Dou

et al.

Molecular Catalysis, Journal Year: 2024, Volume and Issue: 554, P. 113834 - 113834

Published: Jan. 13, 2024

Language: Английский

Citations

2
Photocatalytic Carbamoyl Radical Transfer to Alkenyl Azaarenes DOI
Guangxun Li, Longjun Ma,

Zixuan Yu

et al.

Synlett, Journal Year: 2024, Volume and Issue: 35(16), P. 1883 - 1888

Published: Jan. 29, 2024

Abstract 1-Phenyl-3-azaarenyl-propan-1-amine structural moieties have been widely incorporated in pharmaceuticals and biologically active compounds; however, current synthetic methods to access these compounds need multiple steps proceed with low efficiency. Herein, we reported an efficient photocatalytic carbamoyl radical transfer approach that allows the preparation of high yields (up 88%). The reaction easily runs on a gram-scale was applied for pheniramine two 72% total yield.

Language: Английский

Citations

1
Catalytic Asymmetric Hydrogen Atom Transfer Based on a Chiral Hydrogen Atom Donor Generated from TBADT and Chiral BINOL DOI
Ling Li, Shiqi Zhang, Xin Cui

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

Enantioselective radical reactions mediated by TBADT have seldom been seen due to the inherent challenges. Herein, we disclose a new chiral hydrogen atom transfer (HAT) reagent that was generated easily from 8

Language: Английский

Citations

1
A central functional group-dependent stereoinduction mechanism for chiral super Brønsted C–H acid catalysis DOI
Lihan Zhu, Dongqi Wang

Catalysis Science & Technology, Journal Year: 2023, Volume and Issue: 13(24), P. 7136 - 7148

Published: Jan. 1, 2023

DFT calculations disclosed that the central functional group could induce a favorable chiral environment and determine enantioselectivity for Brønsted C–H acid catalysis.

Language: Английский

Citations

0