Tetrahedron, Год журнала: 2023, Номер 150, С. 133776 - 133776
Опубликована: Дек. 4, 2023
Язык: Английский
Tetrahedron, Год журнала: 2023, Номер 150, С. 133776 - 133776
Опубликована: Дек. 4, 2023
Язык: Английский
Tetrahedron, Год журнала: 2025, Номер 173, С. 134467 - 134467
Опубликована: Янв. 12, 2025
Язык: Английский
Процитировано
3International Journal of Biological Macromolecules, Год журнала: 2023, Номер 254, С. 127997 - 127997
Опубликована: Ноя. 8, 2023
Язык: Английский
Процитировано
43Chinese Chemical Letters, Год журнала: 2024, Номер unknown, С. 109855 - 109855
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
13Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(15), С. 1691 - 1698
Опубликована: Март 19, 2024
Comprehensive Summary A novel electrochemical multicomponent cascade reaction of indole‐tethered alkenes with CF 3 SO 2 Na and n ‐Bu 4 NI has been developed, which enables the rapid assembly spiropyrrolidinyl‐oxindoles in good yields. The experimental results DFT calculations suggest that this proceeds through oxidation Na, radical coupling alkene, spirocyclization, sulfinate, iodide substitution, water coupling. This strategy features mild conditions, easy‐to‐handle reactants, chemical finding not only enriches research contents but also provides a green for construction compared existing methodologies.
Язык: Английский
Процитировано
9Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(14), С. 3050 - 3084
Опубликована: Май 22, 2024
Abstract Tetrahydro‐ β ‐carbolines (TH Cs) also known as tryptolines serve important structural elements in natural products and pharmaceutical compounds, they are utilized drug discovery. They display diverse bioactivities, including anticancer, antifungal, antiparasitic, anti‐ischemic, anti‐inflammatory, other activities. Besides their pharmacological biological significance, these motifs extensively used the production of bioactive compounds. This review is intended to summarize recent advancements chemistry this compound class, synthesis applications organic synthetic intermediates molecules.
Язык: Английский
Процитировано
6ChemCatChem, Год журнала: 2024, Номер 16(14)
Опубликована: Фев. 5, 2024
Abstract The precise synthesis of chiral small molecules is a core research area in chemical science. Deracemization, an appealing technology that converts racemate to its single enantiomer with the same constitution theoretical 100 % yield, appears as straightforward and efficient strategy asymmetric synthesis. A cascading redox sequence was most employed approach drive deracemization through destroy recreate stereocenter given molecule. This review mainly focuses on progress driven by respective biocatalysis chemo–catalysis. In particular, each section will be subdivided according action modes, substrate classes perspectives future development.
Язык: Английский
Процитировано
4Chemical Communications, Год журнала: 2024, Номер 60(37), С. 4902 - 4905
Опубликована: Янв. 1, 2024
Dearomatizative cyclization of indoles: a novel synthetic method for pyrrolo[1,2- ]indole derivatives through visible-light-induced cascade dearomatizative indoles with external nucleophiles has been developed.
Язык: Английский
Процитировано
3The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Март 6, 2025
The synthesis of valuable 2a,3-dihydrobenzo[cd]indolines was successfully achieved by combining IPr-Pdcycle-OxaNaphthyl-catalyzed cross-coupling and proton-induced hydroarylation in a one-pot method. In situ-generated alkynyl-functionalized 3,3-disubstituted indolines were proved as the key intermediate, bearing broad scope substrates with diverse functional groups electronic properties.
Язык: Английский
Процитировано
0Tetrahedron, Год журнала: 2023, Номер 148, С. 133692 - 133692
Опубликована: Окт. 11, 2023
Язык: Английский
Процитировано
6Organic Letters, Год журнала: 2023, Номер 26(1), С. 22 - 28
Опубликована: Дек. 21, 2023
An efficient catalytic strategy toward the synthesis of N-substituted 3-methylindoles from inactive o-dihaloarenes and N-allylamines was developed by using a 1,3-bis(2,6-diisopropylphenyl)acenaphthoimidazol-2-ylidene (AnIPr)-ligated oxazoline palladacycle. It enabled very broad substrate scope tolerating different functional groups, electronic properties, steric bulkiness afforded desired products in good to excellent yields. Importantly, it showed great potential synthesize several bioactive compounds key intermediates natural high
Язык: Английский
Процитировано
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