Efficient activation of N and S co‐doped magnetic biochar for peroxomonosulfate degradation of tetracycline DOI
Xi Zhang, Haoyuan Zheng,

Hong Xu

и другие.

Asia-Pacific Journal of Chemical Engineering, Год журнала: 2024, Номер unknown

Опубликована: Сен. 15, 2024

Abstract N‐S co‐doped magnetic biochar (NSMBC) was synthesized by a two‐step pyrolysis technique and used for the degradation of tetracycline (TC) activated persulfate (peroxomonosulfate [PMS]). Batch experiments showed that temperature doping ratio affected catalytic performance NSMBC. The rate TC in NSMBC/PMS system prepared at 350°C with 33% up to 94.50%, exhibited strong pH adaptability resistance environmental interference. results free radical burst electron paramagnetic resonance (EPR) spectroscopy indicated pathway (SO 4 •− ) degradation. In addition, NSMBC has good stability excellent properties favorable separation recovery. This study not only provides new idea synthesis efficient stable catalysts but also green resourceization pomelo peel waste.

Язык: Английский

Enhanced Breast Cancer Treatment Using Phototherapy and RNS Therapy with Macrophage Membrane-Coated Liposomes DOI Creative Commons
Feiran Wang, Chenhao Li, Xiaodong Xu

и другие.

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 239, С. 113961 - 113961

Опубликована: Май 11, 2024

Breast cancer, the predominant malignancy afflicting women, continues to pose formidable challenges despite advancements in therapeutic interventions. This study elucidates potential of phototherapy, comprising both photothermal and photodynamic therapy (PTT/PDT), as a novel promising modality. To achieve this goal, we devised liposomes coated with macrophage cell membranes including macrophage-associated membrane proteins, which have demonstrated promise biomimetic delivery systems for targeting tumors while preserving their inherent tumor-homing capabilities. integrated system comprised IR780, NONOate, perfluorocarbon. strategic encapsulation aims synergistic combination (PDT) reactive nitrogen species (RNS) therapy. Under near-infrared laser irradiation at 808 nm, IR780 demonstrates its ability prolifically generate oxygen (ROS), superoxide anion (O

Язык: Английский

Процитировано

3

Progress on Carbon Dots with Intrinsic Bioactivities for Multimodal Theranostics DOI Open Access
Hao Zhang, Hao Liu, Xiaohui Liu

и другие.

Advanced Healthcare Materials, Год журнала: 2024, Номер unknown

Опубликована: Окт. 23, 2024

Abstract Carbon dots (CDs) with intrinsic bioactivities are candidates for bioimaging and disease therapy due to their diverse bioactivities, high biocompatibility, multiple functionalities in multimodal theranostics. It is a multidisciplinary research hotspot that includes biology, physics, materials science, chemistry. This progress report discusses the CDs applications The relationship between synthesis structure of summarized analyzed from material chemical perspective. including anti‐tumor, antibacterial, anti‐inflammatory etc. discussed biological points view. Subsequently, optical electronic properties can be applied biomedical field physical Based on functional review CDs, reviewed, diagnosis treatment, activity, Unlike previous reviews, this combines disciplines gain more comprehensive understanding mechanisms, functions, bioactivities.

Язык: Английский

Процитировано

3

Rational Design of NIR‐II Fluorescence/Photoacoustic Nanosensor Tailored for Mechanisms of Diabetes‐Related Breast Cancer DOI Open Access
Ruirui Zhang, Xiao‐Yun Ran, Kang‐Kang Yu

и другие.

Advanced Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 5, 2025

Breast cancer (BC) is the second most common cause of induced death worldwide. Current statistics has disclosed that diabetic BC patients have significantly worse survival rate compared with nondiabetic patients. However, specific mechanism still being explored. Herein, a novel NIR-II nanosensor DNPS for nitric oxide (NO) fluorescence/photoacoustic (FL/PA) imaging capability developed to explore by which diabetes promoting breast progression. In model, exhibits great advantages low intrinsic background, high sensitivity, and deep tissue penetration successfully confirmed expression level NO higher than indicating causes elevated levels in tumor microenvironment. RNA-seq analysis results show hyperglycemia caused leads weakened immune response initiates transcription translation inducible synthase (iNOS) gene produce NO. Besides, increased carcinogens related Nitric 2 (Nos2), such as Spp1, Mmp11, Kitl, develop more rapidly. Here, probe applied first study diabetes-related certain reference value provided subsequent research on progression cancer.

Язык: Английский

Процитировано

0

Carbon dots as smart biosensing and imaging materials delving with antimicrobial, antifungal, and antiviral potentials against infectious pathogens DOI Open Access
Debashis Tripathy, Sagar Kumar Mishra, Shiba Narayan Sahu

и другие.

Journal of the Chinese Chemical Society, Год журнала: 2025, Номер unknown

Опубликована: Янв. 12, 2025

Abstract In the emerging era of infectious diseases, antimicrobials are widely applied against pathogenic microbes (i.e., bacteria, fungus, or virus) to avoid global mortality. Nonetheless, quite a few microbiome adopted genetic mutations over extended period and fostered sustainable resistance towards existing newer antibiotics. Carbon dots (CDs) carbon‐based nanomaterials, unveiled their potential as antifungal, antibacterial, antiviral agents resembled with ease synthesis, reduced toxicity, smart functionalization, high aqueous dispersibility, auspicious biocompatibility. This review has emphasized discussion corroborated types CDs numerous properties tailored biofunctionalization. Further article was featured antiviral, bioimaging, biosensing, anticancer responsiveness (in vivo in vitro mode) followed by biocompatibility, toxicity assessments, challenges, future prospectives.

Язык: Английский

Процитировано

0

Carbon dots derived from organic drug molecules with improved therapeutic effects and new functions DOI
Zhaofan Wu, Xiao-Xiao Luo, Xiaofeng Shi

и другие.

Nanoscale, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This article reviews the functions of drug-derived CDs compared with their precursors and demonstrates broad application prospects in biomedicine.

Язык: Английский

Процитировано

0

Harnessing stimuli-responsive NO nanomaterials for advanced multi-disease therapy DOI
Junjie Zhang, Haiyang Guo, Longguang Tang

и другие.

Coordination Chemistry Reviews, Год журнала: 2025, Номер 533, С. 216540 - 216540

Опубликована: Фев. 27, 2025

Язык: Английский

Процитировано

0

Micro-Nano Convergence-Driven Radiotheranostic Revolution in Hepatocellular Carcinoma DOI
Yisheng Peng,

Hui Liu,

Mengmeng Miao

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Май 10, 2025

Radiotherapy, as an important means of treating hepatocellular carcinoma (HCC), has shown unique therapeutic advantages, especially in patients who are unable to undergo surgery or transplantation. It mainly includes external radiotherapy, transarterial radioembolization and intratumoral radioactive particle implantation. However, under the influence factors such hypoxic characteristics liver tumor microenvironment radioresistance cells, effect radiotherapy may be unstable cause side effects, affecting quality life patients. In recent years, with development nanotechnology, drug delivery systems based on micro-nanomaterials have provided new solutions for improving HCC. Despite this, application micro-nano treatment HCC still faces some challenges, including vivo safety metabolism materials. This article reviews latest progress materials HCC, their radiosensitization clinical translation potential. systematically analyzes role internal sensitization radioimmunotherapy explores advantages

Язык: Английский

Процитировано

0

Perylene tetracarboxylic acid-folate conjugated carbon quantum dots for targeted photodynamic therapy of prostate Cancer DOI
Eman Serag, Sara A. Abdel Gaber, Ayman A. Abdel‐Shafi

и другие.

Bioorganic Chemistry, Год журнала: 2025, Номер 163, С. 108631 - 108631

Опубликована: Май 26, 2025

Язык: Английский

Процитировано

0

Role of carbon dots as nanocarriers in drug delivery: current advancements, prospects, and implementations DOI

Zeshan Ali Sandhu,

Muhammad Asam Raza, Umme Farwa

и другие.

Expert Opinion on Drug Delivery, Год журнала: 2025, Номер unknown

Опубликована: Май 30, 2025

Carbon dots (CDs) are recognized as outstanding nanocarriers for drug delivery owing to their superior biocompatibility, straightforward synthetic routes, and tunable surface properties. This review presents a comprehensive overview of recent developments in CDs within the context systems (DDSs) utilization carriers loading, stabilization, delivery. It also describes functionalized therapeutic applications, including cancer, antimicrobial, gene therapies. Key strategic issues such toxicity, biodistribution, manufacturability thoroughly elaborated critically evaluated identify novel approaches address crucial challenges. The promising potential transform current methods is driving researchers undertake further biological investigations regarding application clinical settings, well explore future prospects biomedical field.

Язык: Английский

Процитировано

0

A NIR light activated self‐reporting carbon dots assembly as phototheranostics for tumor photodynamic therapy DOI Creative Commons

Ziyu Zhao,

Tiejin Chen,

Jian Li

и другие.

Smart Molecules, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Abstract Photodynamic therapy (PDT) has emerged as a promising protocol for cancer therapy. However, real‐time monitoring of PDT progress and accurate determination the optimal treatment timing remain challenges. In this work, we selected carbon dots (CDs) new indocyanine green (IR820) building units to fabricate smart nanotheranostics (CDs‐IR820 assembly) with characteristics controlled release imaging solve time gap between diagnosis treatment. The fabricated CDs‐IR820 assembly locked photosensitivity CDs could degrade under 750 nm laser irradiation achieve CDs, thus used cell producing single oxygen white light. Besides, released migrate from mitochondria nucleus during process, indicating activity, which facilitated regulation parameters precise cancer.

Язык: Английский

Процитировано

2