Abstract
Hydrogen
peroxide
(H
2
O
)
is
a
primary
reactive
oxygen
species
(ROS)
that
can
act
as
chemical
signal
in
developing
and
progressing
serious
life‐threatening
diseases
like
cancer.
Due
to
the
stressful
nature
of
H
,
there
an
urgent
need
develop
sensitive
analytical
approaches
be
applied
various
biological
matrices.
Herein,
portable
point‐of‐care
electrochemical
system
based
on
MXene‐Co
3
4
nanocomposites
detect
different
cancer
cell‐lines
presented.
The
developed
sensor
affordable,
disposable,
highly
selective
for
detection.
This
approach
achieves
dynamic
linear
range
75
µm
with
LOD
0.5
µ
m
LOQ
1.6
.
To
improve
practical
application,
level
ROS
evaluated
both
cell
lines
MDA‐MB‐231
DU145,
respectively,
breast
prostate
cancers,
healthy
HaCat
cells.
Moreover,
same
cells
are
treated
transforming
growth
factor‐β1,
modified
strip
capable
monitorROS
variation.
results
satisfactory
compared
cellular
fluorescent
assay
DCFH/DCFH‐DA.
These
open
new
perspectives
real‐time
monitoring
progression
efficacy
therapy.
ACS Applied Nano Materials,
Год журнала:
2023,
Номер
6(20), С. 19403 - 19413
Опубликована: Окт. 12, 2023
The
excessive
use
of
gatifloxacin
(GAT)
can
seriously
pollute
the
environment
and
damage
human
health.
Therefore,
reliable
detection
its
concentration
is
essential
for
environmental
protection
physical
Herein,
an
efficient
stable
voltammetric
sensor
based
on
zirconium-based
metal–organic
framework/carboxylated
multiwalled
nanotube
nanocomposites
(UiO-66/MWCNT-COOH)
was
constructed
determination
GAT.
morphologies,
microstructures,
electrochemical
properties
UiO-66/MWCNT-COOH
were
investigated
by
using
various
microscopic,
spectroscopic,
techniques.
showed
good
electrocatalytic
activity
GAT
oxidation
with
remarkable
response
signals,
which
primarily
attributed
to
synergistic
effect
from
UiO-66
MWCNT-COOH.
Electrochemical
kinetics
studies
revealed
that
irreversible
diffusion-limited
reaction
involving
two
protons
electrons.
anodic
peak
current
linearly
correlated
in
range
0.05
10
μM
a
low
limit
0.0075
μM.
Moreover,
demonstrated
high
selectivity,
reproducibility,
repeatability
as
well
extraordinary
long-term
stability
(at
least
7
weeks).
proposed
reliably
detected
trace
effluent,
milk,
serum,
eye
drops
satisfactory
recoveries.
Together
outstanding
merits
such
cost,
robust
response,
short
assay
time,
sensitivity,
shows
enormous
prospects
situ
multiple
antibiotics.
ACS Applied Nano Materials,
Год журнала:
2023,
Номер
6(18), С. 17040 - 17052
Опубликована: Сен. 6, 2023
The
excessive
use
of
levofloxacin
(LEV)
can
lead
to
significant
environmental
pollution,
while
also
damaging
human
health.
accurate
detection
its
concentration
is
therefore
essential
protect
both
the
environment
and
Herein,
we
report
simple
synthesis
α-zirconium
phosphate
supported
on
nitrogen-doped
graphene
nanosheets
(α-ZrP/NG)
application
in
voltammetric
determination
trace
LEV
real
samples.
surface
morphology,
microstructure,
electrochemical
properties
α-ZrP/NG
were
investigated
by
microscopic
spectroscopic
techniques.
analytical
parameters,
including
accumulation
potential,
time,
loading
volume,
buffer
pH,
optimized
improve
electrocatalytic
sensing
performance
α-ZrP/NG.
Owing
synergetic
interaction
between
α-ZrP
NG,
proposed
sensor
exhibited
an
excellent
activity
for
electrical
oxidation
LEV.
In
range
0.01–5.0
μM,
anodic
peak
current
increased
linearly
with
increase
concentration,
limit
was
2.6
nmol
L–1.
Finally,
levels
wastewater,
serum,
milk,
eye
drop
samples
determined
using
system
combined
a
glassy
carbon
electrode
give
satisfactory
recoveries
(98.48–103.2%),
indicating
that
prepared
demonstrates
promise
environmental,
food,
drug
monitoring
applications.
Micromachines,
Год журнала:
2023,
Номер
14(2), С. 247 - 247
Опубликована: Янв. 18, 2023
The
first
two-dimensional
(2D)
substance
sparked
a
boom
in
research
since
this
type
of
material
showed
potential
promise
for
applications
field
sensors.
A
class
2D
transition
metal
nitrides,
carbides,
and
carbonitrides
are
referred
to
as
MXenes.
Following
the
2011
synthesis
Ti3C2
from
Ti3AlC2,
much
has
been
published.
Since
these
materials
have
several
advantages
over
conventional
materials,
they
extensively
researched,
synthesized,
studied
by
many
organizations.
To
give
readers
general
understanding
well-liked
review
examines
structures
MXenes,
discusses
various
procedures,
analyzes
physicochemistry
properties,
particularly
optical,
electronic,
structural,
mechanical
properties.
focus
is
analysis
modern
advancements
development
MXene-based
sensors,
including
electrochemical
gas
biosensors,
optical
wearable
Finally,
opportunities
challenges
further
study
on
creation
MXenes-based
sensors
discussed.
Chemical Reviews,
Год журнала:
2024,
Номер
124(22), С. 12738 - 12843
Опубликована: Ноя. 5, 2024
The
quest
to
imbue
machines
with
intelligence
akin
that
of
humans,
through
the
development
adaptable
neuromorphic
devices
and
creation
artificial
neural
systems,
has
long
stood
as
a
pivotal
goal
in
both
scientific
inquiry
industrial
advancement.
Recent
advancements
flexible
electronics
primarily
rely
on
nanomaterials
polymers
owing
their
inherent
uniformity,
superior
mechanical
electrical
capabilities,
versatile
functionalities.
However,
this
field
is
still
its
nascent
stage,
necessitating
continuous
efforts
materials
innovation
device/system
design.
Therefore,
it
imperative
conduct
an
extensive
comprehensive
analysis
summarize
current
progress.
This
review
highlights
applications
neuromorphics,
involving
inorganic
(zero-/one-/two-dimensional,
heterostructure),
carbon-based
such
carbon
nanotubes
(CNTs)
graphene,
polymers.
Additionally,
comparison
summary
structural
compositions,
design
strategies,
key
performance,
significant
these
are
provided.
Furthermore,
challenges
future
directions
pertaining
materials/devices/systems
associated
neuromorphics
also
addressed.
aim
shed
light
rapidly
growing
attract
experts
from
diverse
disciplines
(e.g.,
electronics,
science,
neurobiology),
foster
further
for
accelerated
development.
