Journal of Photochemistry and Photobiology A Chemistry, Год журнала: 2024, Номер unknown, С. 116169 - 116169
Опубликована: Ноя. 1, 2024
Язык: Английский
Journal of Photochemistry and Photobiology A Chemistry, Год журнала: 2024, Номер unknown, С. 116169 - 116169
Опубликована: Ноя. 1, 2024
Язык: Английский
Dyes and Pigments, Год журнала: 2024, Номер 228, С. 112229 - 112229
Опубликована: Май 15, 2024
Язык: Английский
Процитировано
13Journal of Photochemistry and Photobiology A Chemistry, Год журнала: 2024, Номер 453, С. 115650 - 115650
Опубликована: Апрель 1, 2024
Язык: Английский
Процитировано
5RSC Advances, Год журнала: 2025, Номер 15(12), С. 9129 - 9140
Опубликована: Янв. 1, 2025
A novel indolium based low-cost and portable sensor for the colorimetric fluorogenic detection of cyanide ions.
Язык: Английский
Процитировано
0Inorganic Chemistry Communications, Год журнала: 2024, Номер 163, С. 112330 - 112330
Опубликована: Апрель 5, 2024
Язык: Английский
Процитировано
3Biosensors, Год журнала: 2024, Номер 14(5), С. 244 - 244
Опубликована: Май 13, 2024
A novel indolium-based fluorescent probe for the detection of CN− was developed based on conjugation 1, 2, 3, 3-Tetramethyl-3H-indolium iodide and 2-acetyl benzothiophene. The introduction external caused a nucleophilic attack to quaternary amine salt structure in resulted departure ions steric rotation index group, which fluorescence quenching. titration experiments showed that had rapid qualitative quantitative analysis capabilities CN−. Moreover, relevant biocompatibility also demonstrated potential application value probe.
Язык: Английский
Процитировано
3Analytical Methods, Год журнала: 2024, Номер 16(28), С. 4880 - 4888
Опубликована: Янв. 1, 2024
A simple ferrocene-based chemo-dosimeter was developed to selectively sense CN − in an aqueous solution colourimetrically and electrochemically, served as a tool determine cyanide content cassava flour.
Язык: Английский
Процитировано
3Dyes and Pigments, Год журнала: 2024, Номер unknown, С. 112567 - 112567
Опубликована: Ноя. 1, 2024
Язык: Английский
Процитировано
3Journal of Photochemistry and Photobiology A Chemistry, Год журнала: 2025, Номер unknown, С. 116295 - 116295
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0ACS Chemical Neuroscience, Год журнала: 2025, Номер unknown
Опубликована: Март 19, 2025
The cholinergic deficits and deposition of β-amyloid (Aβ) species are regarded as the key events contributing to progression Alzheimer's disease (AD). Herein, a series novel donor-acceptor architecture-type potential theranostic agents were designed, synthesized, evaluated for their against cholinesterase (ChE) enzymes detection Aβ species, which primary targets in development therapeutics AD. optimal compound/probe 18 containing benzothiazolium fluorophore with bifunctional electron-donating N-aryl piperazine scaffold exhibited potent inhibitory activities acetylcholinesterase (AChE; IC50 = 0.172 ± 0.011 μM) butyrylcholinesterase (BuChE; 1.376 0.141 μM). Measurement fluorescence properties showed that probe emission maxima (λem) >610 nm dimethyl sulfoxide (DMSO) >590 PBS, suitable imaging. In vitro studies demonstrated change characteristics high binding affinities (18; Kd 0.731 upon aggregates. affinity toward aggregates was further observed elavGAL4 > UAS Aβ, Drosophila larval brain sections, using imaging technique. vivo acute oral toxicity evaluation indicated safety profile lead 18. Moreover, behavioral including Y-maze object recognition tests signified administration compound improved cognitive spatial memory impairment at dose 10 20 mg/kg scopolamine-induced deficit model.
Язык: Английский
Процитировано
0Analytical and Bioanalytical Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Апрель 3, 2025
Abstract A hemicyanine-based colorimetric and fluorometric sensor, 2-(2-(2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecin-12-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide (MH-5), was developed synthesized to detect Li + CN − ions in DMSO-PBS buffer solution (10 mM, pH 7.25, v/v 1:9). MH-5 displayed a rapid highly selective response both , indicated by distinct color change from pink pale the presence of colorless upon detection, without interference other cations or anions. The interaction mechanisms with were investigated using various analytical techniques, including 1 H NMR, ESI–MS, FT-IR spectroscopy, Job’s plot analysis. These studies suggest that is detected through nucleophilic addition indolium moiety MH-5, while detection occurs via coordination oxygen atoms crown ether structure. fluorescence-based limits for determined be 0.150 µM 0.154 µM, respectively. Additionally, evaluated living cells, demonstrating effective cell penetration reliable potential bio-imaging applications. Graphical
Язык: Английский
Процитировано
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