Swift and quantitative naked-eye detection of cyanide: a dual-mode approach using an ICT-based colorimetric and ratiometric fluorescent chemodosimeter

Dyes and Pigments, Journal Year: 2024, Volume and Issue: 228, P. 112229 - 112229

Published: May 15, 2024

Language: Английский

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Rationally designed dual channel reversible probe for cyanide recognition in aqueous medium with solid-state sensing abilities

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 453, P. 115650 - 115650

Published: April 1, 2024

Language: Английский

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An indolium inspired portable colorimetric sensor for cyanide recognition in environmental samples with smartphone integration

RSC Advances, Journal Year: 2025, Volume and Issue: 15(12), P. 9129 - 9140

Published: Jan. 1, 2025

A novel indolium based low-cost and portable sensor for the colorimetric fluorogenic detection of cyanide ions.

Language: Английский

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A ferrocene-based chemo-dosimeter for colorimetric and electrochemical detection of cyanide and its estimation in cassava flour

Analytical Methods, Journal Year: 2024, Volume and Issue: 16(28), P. 4880 - 4888

Published: Jan. 1, 2024

A simple ferrocene-based chemo-dosimeter was developed to selectively sense CN − in an aqueous solution colourimetrically and electrochemically, served as a tool determine cyanide content cassava flour.

Language: Английский

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Intermolecular C–H···O hydrogen bond–induced H-aggregates for rapid, real-time detection of cyanide

Dyes and Pigments, Journal Year: 2024, Volume and Issue: unknown, P. 112567 - 112567

Published: Nov. 1, 2024

Language: Английский

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A sensitive colorimetric and “OFF-ON” fluorescent sensor for cyanide ions based on ESIPT-AIE mechanism from a fluorene-hydroxybenzaldehyde Schiff base

Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 116295 - 116295

Published: Jan. 1, 2025

Language: Английский

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Development of Donor–Acceptor Architecture-Based Potential Theranostic Fluorescent Probes for Alzheimer’s Disease

ACS Chemical Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

The cholinergic deficits and deposition of β-amyloid (Aβ) species are regarded as the key events contributing to progression Alzheimer's disease (AD). Herein, a series novel donor-acceptor architecture-type potential theranostic agents were designed, synthesized, evaluated for their against cholinesterase (ChE) enzymes detection Aβ species, which primary targets in development therapeutics AD. optimal compound/probe 18 containing benzothiazolium fluorophore with bifunctional electron-donating N-aryl piperazine scaffold exhibited potent inhibitory activities acetylcholinesterase (AChE; IC50 = 0.172 ± 0.011 μM) butyrylcholinesterase (BuChE; 1.376 0.141 μM). Measurement fluorescence properties showed that probe emission maxima (λem) >610 nm dimethyl sulfoxide (DMSO) >590 PBS, suitable imaging. In vitro studies demonstrated change characteristics high binding affinities (18; Kd 0.731 upon aggregates. affinity toward aggregates was further observed elavGAL4 > UAS Aβ, Drosophila larval brain sections, using imaging technique. vivo acute oral toxicity evaluation indicated safety profile lead 18. Moreover, behavioral including Y-maze object recognition tests signified administration compound improved cognitive spatial memory impairment at dose 10 20 mg/kg scopolamine-induced deficit model.

Language: Английский

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A hemicyanine-based dual-responsive fluorescent sensor for the detection of lithium and cyanide ions: application in living cells

Analytical and Bioanalytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Abstract A hemicyanine-based colorimetric and fluorometric sensor, 2-(2-(2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecin-12-yl)vinyl)-3,3-dimethyl-1-propyl-3H-indol-1-ium iodide (MH-5), was developed synthesized to detect Li + CN − ions in DMSO-PBS buffer solution (10 mM, pH 7.25, v/v 1:9). MH-5 displayed a rapid highly selective response both , indicated by distinct color change from pink pale the presence of colorless upon detection, without interference other cations or anions. The interaction mechanisms with were investigated using various analytical techniques, including 1 H NMR, ESI–MS, FT-IR spectroscopy, Job’s plot analysis. These studies suggest that is detected through nucleophilic addition indolium moiety MH-5, while detection occurs via coordination oxygen atoms crown ether structure. fluorescence-based limits for determined be 0.150 µM 0.154 µM, respectively. Additionally, evaluated living cells, demonstrating effective cell penetration reliable potential bio-imaging applications. Graphical

Language: Английский

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A specific, ultra-sensitive and rapid naked-eye on-site recognition of CN– and Cu2+ ions in tap water using an isonicotinohydrazide-salisaldehyde hybrid probe

Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 163, P. 112330 - 112330

Published: April 5, 2024

Language: Английский

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A Novel Indolium-Based Fluorescent Probe for Fast Detection of Cyanide

Biosensors, Journal Year: 2024, Volume and Issue: 14(5), P. 244 - 244

Published: May 13, 2024

A novel indolium-based fluorescent probe for the detection of CN− was developed based on conjugation 1, 2, 3, 3-Tetramethyl-3H-indolium iodide and 2-acetyl benzothiophene. The introduction external caused a nucleophilic attack to quaternary amine salt structure in resulted departure ions steric rotation index group, which fluorescence quenching. titration experiments showed that had rapid qualitative quantitative analysis capabilities CN−. Moreover, relevant biocompatibility also demonstrated potential application value probe.

Language: Английский

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