Journal of Applied Polymer Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 17, 2024
Abstract
The
iron
oxide
nanoparticles
(IONs),
coated
with
different
materials,
are
synthesized
and
utilized
as
nucleating
agents
to
prepare
magnetic
multi‐modal
porous
scaffolds
of
poly
(lactic‐
co
‐glycolic
acid)/IONs
using
the
supercritical
carbon
dioxide
(ScCO
2
)
foaming
process.
effects
modification
including
citric
acid,
polycaprolactone,
polyvinyl
acetate,
on
process
properties
systematically
investigated.
results
indicate
that
solubility
diffusion
ability
CO
in
materials
played
a
vital
role
use
‐philic
high
pressure
proves
beneficial
generating
micropores.
structures
can
be
obtained
at
relatively
low
for
ScCO
systems
evaluated
this
study.
Furthermore,
prepared
exhibit
porosity
good
compressive
modulus
(higher
than
0.4
MPa),
satisfying
requirements
tissue
engineering
soft
scaffolds.
Dental Materials Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
block-type
of
three-dimensional
carbonate
apatite
bone
graft
(3D-CO3Ap)
is
demanded
for
applying
large
defects.
Although
we
fabricated
the
3D-CO3Ap
with
high
mechanical
strength
by
fusing
polymer-bound
spherical
precursor,
optimized
condition
has
not
yet
been
found.
In
this
study,
indicated
controlling
granular
packing
ratio
(i.e.,
different
compression
ratios
mold
volume
from
100%
to
140%).
was
obtained
in
110%
130%,
even
though
block
collapsed
and
complete
conversion
CO3Ap
achieved
140%.
The
highest
compressive
130%
because
intergranular
connection
area
most
enhanced.
Furthermore,
when
reconstructing
defects,
prevented
soft
tissue
penetration
showed
good
osteoconductivity
their
controlled
pore
size.
optimal
achieving
both
osteoconductivity.
Chemical Engineering Journal,
Год журнала:
2024,
Номер
494, С. 152916 - 152916
Опубликована: Июнь 12, 2024
Losing
an
eye
to
various
reasons
at
any
age
may
have
a
major
impact
on
one's
self-image,
except
for
requiring
adapt
monocular
vision.
The
conventional
metal
oxide
or
polymer
implants
orbital
reconstruction,
involving
the
vulnerable
postoperative
administration
(migration,
exposure),
are
always
challenged
due
deficiency
of
some
critical
efficacy
attainability.
While
coralline
hydroxyapatite
ceramics
offer
alternatives,
they
come
with
insufficient
infection
prevention
and
tailor-made
manufacture.
This
underscores
insistent
need
personized
multifunctional
materials.
In
this
context,
functional
emerging
as
promising
solution
especially
accompanying
self-antibacterial
sufficient
integration
host
tissue.
Herein
we
developed
porous
Ca-Zn-silicate
bioceramic
seamlessly
clinical
requirements.
Our
study
introduced
dilute
magnesium
dopant
into
hardystonite
(Ca2ZnSi2O7;
HT)
fabricated
precisely
tuning
gradient
pore
architectures
(Triply
radial
structures)
via
digital
light
processing
technique.
Notably,
benefiting
from
its
topologies
chemical
compositions,
our
investigations
unveiled
proposed
HT-based
containing
4
%Mg
substitution
yielded
desirable
surface
reactivity,
affording
prominent
anti-inflammatory
antibacterial
properties
rapid
vascularization
(within
2
weeks
after
implantation),
in
comparison
clinically
available
polymeric
products
(MEDPOR®
&
Hydroxyapatite®).
Beyond
this,
exhibited
exceptional
structural
stability
biocompatibility
vitro
vivo.
Given
these
impressive
attributes,
findings
hold
potential
revolutionizing
field
reconstruction
medicine,
offering
next-generation
advanced
silicate
bioceramics
crafting
personizing
precise
implantation
strategy.
Journal of Thermoplastic Composite Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 9, 2024
Biomimetic
nanoparticles
(BioM
NPs)
are
an
innovative
strategy
for
nanomedicine
(NanoMed)
that
combines
the
advantages
of
artificial
materials
with
biological
functioning
natural
systems.
Ongoing
research
attempts
to
enhance
their
design,
and
stability,
solve
problems
broader
applications
in
medicine
biotechnology.
NanoMed
ideas
intensively
researched
preclinical
because
they
provide
unique
disease
management.
It
has
developed
novel
therapeutic
strategies
combating
viral
infections
increasing
treatment
success
rates.
The
creation
nanocarriers
drug
delivery
systems
is
critical
evolution
NanoMed,
but
there
still
much
learn
about
this
quickly
evolving
field.
To
contribute
existing
knowledge
cover
gaps,
our
present
review
article
will
discuss
state-of-the-art
BioM
NPs
three
sections.
First,
methods
NP
production
synergistic
interactions
human
cells,
tissues,
organs,
organ
be
discussed.
Followed
by
a
discussion
several
NanoMeds
(wound
healing,
targeted
delivery,
theranostics,
cancer
therapy,
bone
formation
and/or
regeneration),
concluding
application
NPs,
challenges
associated
these
applications,
prospects.
