Development of a magnetic biomimetic scaffold for improved bone regeneration via static magnetic stimulation DOI
Miguel Flores, Tiago P. Ribeiro, Sara Madureira

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Highly biologically functional magnesium silicate-coated 3D printed round pore-shaped titanium scaffold alters exosomal miRNA expression to promote osteogenic differentiation for bone defect repair DOI

Xuwei Luo,

Zhencheng Xiong, Dong Wang

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 489, P. 151372 - 151372

Published: April 17, 2024

Language: Английский

Citations

6
Development and characterization of nano-hydroxyapatite/gelatin/PVA/alginate-based multifunctional active scaffolds for bone regeneration: An in vitro and in vivo study DOI
Nadia R El-Bahrawy, Ahmed Hafez, Ahmed Elmekawy

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141160 - 141160

Published: Feb. 1, 2025

Language: Английский

Citations

0
Optimization of the structure of three-dimensional interconnected porous carbonate apatite bone grafts with spherical granules DOI Open Access

Saki Takeda,

Akira Tsuchiya, Masafumi Moriyama

et al.

Dental Materials Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A block-type of three-dimensional carbonate apatite bone graft (3D-CO3Ap) is demanded for applying large defects. Although we fabricated the 3D-CO3Ap with high mechanical strength by fusing polymer-bound spherical precursor, optimized condition has not yet been found. In this study, indicated controlling granular packing ratio (i.e., different compression ratios mold volume from 100% to 140%). was obtained in 110% 130%, even though block collapsed and complete conversion CO3Ap achieved 140%. The highest compressive 130% because intergranular connection area most enhanced. Furthermore, when reconstructing defects, prevented soft tissue penetration showed good osteoconductivity their controlled pore size. optimal achieving both osteoconductivity.

Language: Английский

Citations

0
Divergent Effects of Premineralization and Prevascularization on Osteogenesis and Vascular Integration in Humanized Tissue Engineered Bone Constructs DOI

Sugandha Bhatia,

Luke Hipwood,

Briony Claxton

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Porous metal materials for applications in orthopedic field: A review on mechanisms in bone healing DOI Creative Commons
Yutong Ma, Yì Wáng, Shuang Tong

et al.

Journal of Orthopaedic Translation, Journal Year: 2024, Volume and Issue: 49, P. 135 - 155

Published: Oct. 11, 2024

Language: Английский

Citations

2
Engineering self-antimicrobial implants with precision pore architectures for personized orbital reconstruction DOI Creative Commons
Menglu Chen, Jingyi Wang,

Yiyu Peng

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 494, P. 152916 - 152916

Published: June 12, 2024

Losing an eye to various reasons at any age may have a major impact on one's self-image, except for requiring adapt monocular vision. The conventional metal oxide or polymer implants orbital reconstruction, involving the vulnerable postoperative administration (migration, exposure), are always challenged due deficiency of some critical efficacy attainability. While coralline hydroxyapatite ceramics offer alternatives, they come with insufficient infection prevention and tailor-made manufacture. This underscores insistent need personized multifunctional materials. In this context, functional emerging as promising solution especially accompanying self-antibacterial sufficient integration host tissue. Herein we developed porous Ca-Zn-silicate bioceramic seamlessly clinical requirements. Our study introduced dilute magnesium dopant into hardystonite (Ca2ZnSi2O7; HT) fabricated precisely tuning gradient pore architectures (Triply radial structures) via digital light processing technique. Notably, benefiting from its topologies chemical compositions, our investigations unveiled proposed HT-based containing 4 %Mg substitution yielded desirable surface reactivity, affording prominent anti-inflammatory antibacterial properties rapid vascularization (within 2 weeks after implantation), in comparison clinically available polymeric products (MEDPOR® & Hydroxyapatite®). Beyond this, exhibited exceptional structural stability biocompatibility vitro vivo. Given these impressive attributes, findings hold potential revolutionizing field reconstruction medicine, offering next-generation advanced silicate bioceramics crafting personizing precise implantation strategy.

Language: Английский

Citations

1
Physical and histological comparison of three-dimensional interconnected porous carbonate apatite bone graft fabricated with cylindrical and spherical granules DOI
S. Takeda, Akira Tsuchiya, Masafumi Moriyama

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

1
Nature-inspired solutions: A comprehensive review of biomimetic nanoparticles in nanomedicine DOI
Eliasu Issaka,

Blessing Tornyeava,

Enock Adjei Agyekum

et al.

Journal of Thermoplastic Composite Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 9, 2024

Biomimetic nanoparticles (BioM NPs) are an innovative strategy for nanomedicine (NanoMed) that combines the advantages of artificial materials with biological functioning natural systems. Ongoing research attempts to enhance their design, and stability, solve problems broader applications in medicine biotechnology. NanoMed ideas intensively researched preclinical because they provide unique disease management. It has developed novel therapeutic strategies combating viral infections increasing treatment success rates. The creation nanocarriers drug delivery systems is critical evolution NanoMed, but there still much learn about this quickly evolving field. To contribute existing knowledge cover gaps, our present review article will discuss state-of-the-art BioM NPs three sections. First, methods NP production synergistic interactions human cells, tissues, organs, organ be discussed. Followed by a discussion several NanoMeds (wound healing, targeted delivery, theranostics, cancer therapy, bone formation and/or regeneration), concluding application NPs, challenges associated these applications, prospects.

Language: Английский

Citations

1
Preparation of magnetic scaffolds via supercritical carbon dioxide foaming process using iron oxide nanoparticles coated with CO2‐philic materials as nucleating agents DOI
Zhen Jiao, Shuo Zhang, Jinjing Wang

et al.

Journal of Applied Polymer Science, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Abstract The iron oxide nanoparticles (IONs), coated with different materials, are synthesized and utilized as nucleating agents to prepare magnetic multi‐modal porous scaffolds of poly (lactic‐ co ‐glycolic acid)/IONs using the supercritical carbon dioxide (ScCO 2 ) foaming process. effects modification including citric acid, polycaprolactone, polyvinyl acetate, on process properties systematically investigated. results indicate that solubility diffusion ability CO in materials played a vital role use ‐philic high pressure proves beneficial generating micropores. structures can be obtained at relatively low for ScCO systems evaluated this study. Furthermore, prepared exhibit porosity good compressive modulus (higher than 0.4 MPa), satisfying requirements tissue engineering soft scaffolds.

Language: Английский

Citations

0
Development of a magnetic biomimetic scaffold for improved bone regeneration via static magnetic stimulation DOI
Miguel Flores, Tiago P. Ribeiro, Sara Madureira

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0