Targeting Hydrogel for Intelligent Recognition and Spatiotemporal Control in Cell‐Based Therapeutics

Advanced Science, Год журнала: 2024, Номер 11(30)

Опубликована: Июнь 14, 2024

Abstract Smart drug platforms based on spatiotemporally controlled release and integration of tumor imaging are expected to overcome the inefficiency uncertainty traditional theranostic modes. In this study, a composite consisting thermosensitive hydrogel (polyvinyl alcohol‐carboxylic acid (PCF)) multifunctional nanoparticle (Fe 3 O 4 @Au/Mn(Zn)‐4‐carboxyphenyl porphyrin/polydopamine (FAM x P)) is developed combine immunogenic cell death (ICD)/immune checkpoint blockade (ICB) therapy under guidance magnetic resonance (MRI) fluorescence (FI). It can not only further recognize target cells through folate receptor cells, but also produce thermal dissolution after exposure near‐infrared light slowly FAM P in situ, thereby prolonging treatment time avoiding recurrence. As entered it released pH‐dependent manner. Chemodynamic, photothermal photodynamic cause significant ICD cancer cells. ICB thus be enhanced by injecting anti‐programmed ligand 1, improving effectiveness treatment. The PCF‐FAM may represent an updated design approach with simple compositions for cooperative MRI/FI‐guided targeted therapeutic pathways tumors.

Язык: Английский

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Applied research and recent advances in the development of flexible sensing hydrogels from cellulose: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136100 - 136100

Опубликована: Окт. 24, 2024

Язык: Английский

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Advances in photo-responsive hydrogel integrated with biomedical materials for antitumor applications

European Polymer Journal, Год журнала: 2024, Номер 220, С. 113431 - 113431

Опубликована: Сен. 3, 2024

Язык: Английский

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Adhesive conductive wood-based hydrogel with high tensile strength as a flexible sensor

Carbohydrate Polymers, Год журнала: 2024, Номер 351, С. 122954 - 122954

Опубликована: Ноя. 14, 2024

Язык: Английский

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A Shikonin-Iron-Tragacanth gum nanocomplex for synergistic treatment of bladder cancer

Chemical Engineering Journal, Год журнала: 2025, Номер 505, С. 159202 - 159202

Опубликована: Янв. 5, 2025

Язык: Английский

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Transdermal Delivery of Resveratrol by a Nanomicelle-Loaded Enzyme-Triggered Hydrogel for Diabetic Wound Healing

ACS Applied Nano Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Язык: Английский

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Cellulose-based hydrogels in cancer diagnostic and therapy

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 307 - 325

Опубликована: Янв. 1, 2025

Язык: Английский

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Tailoring of a specific pH-induced self-enhanced photothermal cellulose hydrogel for antibiotic-resistant bacteria-infected wound treatment

Chemical Engineering Journal, Год журнала: 2025, Номер 513, С. 163025 - 163025

Опубликована: Апрель 23, 2025

Язык: Английский

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Injectable natural hydrogel with spatiotemporal self-strengthening, antibacterial and anti-inflammatory properties for treating diabetic wound

Chemical Engineering Journal, Год журнала: 2024, Номер 497, С. 154802 - 154802

Опубликована: Авг. 13, 2024

Язык: Английский

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One-step construction of silver nanoparticles immersed hydrogels by triple-helix β-glucans and the application in infectious wound healing

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 137146 - 137146

Опубликована: Окт. 1, 2024

Язык: Английский

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