Chemical Proteomics Reveals That Camptothecin Weakens Insect Immunity against Bacteria by Suppressing Antimicrobial Peptide Expression DOI
Huan Liu, Yi Ding,

Dongdong Huang

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 27, 2024

Plant natural products are crucial in defending against herbivorous insects and widely used pest control, yet their mechanisms remain complex insufficiently studied. This study employed a reverse strategy to investigate the mechanism of camptothecin (CPT), botanical pesticide. By using CPT-based chemical probe coupled with proteomic analysis, immune-related proteins, including those involved prophenoloxidase (PPO) activation antimicrobial peptide (AMP) synthesis, were identified Asian corn borer, Ostrinia furnacalis. The findings demonstrated that CPT weakens insect immunity, primarily by inhibiting AMP synthesis rather than affecting PPO activation. Specifically, downregulated expression genes IMD pathway encoding AMPs (attacin gloverin). Additionally, CPT-fed exhibited reduced antibacterial activity. research uncovers novel as an immunosuppressant, offering new insights may enhance application control.

Язык: Английский

Macromolecules-based encapsulation of pesticides with carriers: A promising approach for safe and effective delivery DOI
Roohallah Saberi Riseh,

Masoumeh Vatankhah,

Mohadeseh Hassanisaadi

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 269, С. 132079 - 132079

Опубликована: Май 3, 2024

Язык: Английский

Процитировано

9

Cellulase-responsive hydroxypropyl cellulose-anchored hollow mesoporous silica carriers for pesticide delivery DOI
Ziwei Wu, Yiyang Chen, Xue Gong

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 277, С. 134612 - 134612

Опубликована: Авг. 8, 2024

Язык: Английский

Процитировано

4

Two Birds with One Stone: Eco‐Friendly Nano‐Formulation Endows a Commercial Fungicide with Excellent Insecticidal Activity DOI Open Access

Dongdong Huang,

Huitang Qi,

Huan Liu

и другие.

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 28, 2025

Abstract The development of multi‐action pesticides presents significant advantages, including cost‐effectiveness, reduced application frequency, enhanced resistance management, and minimized environmental impact. Despite its efficacy in targeting chitin synthase both fungi insects, the insecticidal performance polyoxin B remains limited. To overcome this limitation, a novel nano‐formulation, B@ZTS is developed, utilizing agricultural byproducts, tea saponin, zein. This formulation features small particle size, high leaf deposition efficiency, excellent dispersion properties. Leveraging disulfide bond system, designed to respond intracellular reducing environment, enabling controlled release B. Remarkably, nano‐formulation facilitates penetration physiological barriers, achieving equivalent fungicidal at only one‐fifth dosage. work highlights potential eco‐friendly, cost‐effective, multifunctional nano‐pesticides, providing compelling solution for sustainable practices demonstrating broad applicability integrated pest disease management.

Язык: Английский

Процитировано

0

Zein and resveratrol Schiff base nanocomplexes: An efficient delivery system to enhance the antibacterial efficacy of berberine DOI
Peng Ju,

Leliang Zhou,

Jixiang Chen

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 306, С. 141496 - 141496

Опубликована: Фев. 26, 2025

Язык: Английский

Процитировано

0

Multiresponsive Zein Nanospheres for Avermectin B2 Delivery: Enhancing Root-Knot Nematode Control and Safety to Nontarget Organisms DOI
Xiquan Ding, Qian Du, Fei Gao

и другие.

ACS Nano, Год журнала: 2025, Номер unknown

Опубликована: Апрель 14, 2025

Root-knot nematodes are globally prevalent plant-parasitic pests, distinguished by their widespread distribution, extensive host range, and challenging control measures. Avermectin B2, one of the few effective nematicides available, faces limitations in efficacy poses environmental concerns due to its eco-unfriendly composition poor utilization traditional emulsifiable concentrate (EC) formulations. In this study, we developed core-shell structured Ave B2-BS@Zein@SC nanospheres, incorporating zein as carrier, sodium caseinate stabilizer, butyl stearate temperature "switch". These nanospheres demonstrated multiresponsive characteristics temperature, pH, enzymatic conditions, facilitating rapid pesticide release under elevated temperatures, mildly acidic or alkaline presence protease. controlled-release properties effectively responded both factors during nematode outbreaks intestinal conditions nematodes, enhancing targeting efficiency. The engineered improved mobility stability avermectin B2 soil, enabling more comprehensive across broader deeper soil layers. Additionally, penetration capability into plant roots eliminated that had already invaded root system, thereby strengthening crop protection. Crucially, enhanced safety for nontarget organisms. This environmentally conscious, nanodelivery system presents a promising strategy sustainable subterranean pest management.

Язык: Английский

Процитировано

0

Tea tree oil Pickering emulsions stabilized by sodium lignosulfonate-zein covalent conjugate for fungicide delivery and enhanced control efficacy against peanut sclerotium blight DOI
Jihao Zuo,

Yitong Lin,

Jiayuan Tian

и другие.

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162876 - 162876

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Influence of Nanopesticide Surface Chemistry on Adsorption to Plant Cuticle and Wax Layer: The Role of Zeta Potential and Wetting DOI
Yashwanth Arcot, Minchen Mu,

Monica Iepure

и другие.

Surfaces and Interfaces, Год журнала: 2024, Номер unknown, С. 105190 - 105190

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

0

pH/Enzyme-responsive nanocarrier pesticide delivery system: Realizing targeted release in pest gut for enhanced Apis cerana safety DOI

Pengrui Du,

Xuehua Shao, Hao Wu

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 503, С. 158419 - 158419

Опубликована: Дек. 8, 2024

Язык: Английский

Процитировано

0

Bioavailability and Environmental Safety of Nanoinsecticides DOI

R. Anbalagan,

Jayalakshmi Krishnan, Swathy Kannan

и другие.

Nanotechnology in the life sciences, Год журнала: 2024, Номер unknown, С. 147 - 165

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Chemical Proteomics Reveals That Camptothecin Weakens Insect Immunity against Bacteria by Suppressing Antimicrobial Peptide Expression DOI
Huan Liu, Yi Ding,

Dongdong Huang

и другие.

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 27, 2024

Plant natural products are crucial in defending against herbivorous insects and widely used pest control, yet their mechanisms remain complex insufficiently studied. This study employed a reverse strategy to investigate the mechanism of camptothecin (CPT), botanical pesticide. By using CPT-based chemical probe coupled with proteomic analysis, immune-related proteins, including those involved prophenoloxidase (PPO) activation antimicrobial peptide (AMP) synthesis, were identified Asian corn borer, Ostrinia furnacalis. The findings demonstrated that CPT weakens insect immunity, primarily by inhibiting AMP synthesis rather than affecting PPO activation. Specifically, downregulated expression genes IMD pathway encoding AMPs (attacin gloverin). Additionally, CPT-fed exhibited reduced antibacterial activity. research uncovers novel as an immunosuppressant, offering new insights may enhance application control.

Язык: Английский

Процитировано

0